Loss of the sex chromosome in human neoplasias of the nervous system
Autor(a) principal: | |
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Data de Publicação: | 1994 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/223974 |
Resumo: | Thirty-eight tumors (five grade I-II astrocytomas, three grade III astrocytomas, four glioblastomas, one oligodendroglioma, four ependymomas, one pineocytoma, three medulloblastomas, four acoustic nerve neurinomas, one intraspinal neurinoma, one neurofibroma, 10 meningiomas, and one craniopharyngioma) and three benign lesions of the nervous system were evaluated cytogenetically after in vitro culture. Sex chromosome loss was detected in 56% of the cases (-X in 13 of the 25 female patients and -Y in nine of the 16 male patients). The objective of the present report was to study the role of this abnormality in cells of the nervous system. |
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Repositório Institucional da UNESP |
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spelling |
Loss of the sex chromosome in human neoplasias of the nervous systemThirty-eight tumors (five grade I-II astrocytomas, three grade III astrocytomas, four glioblastomas, one oligodendroglioma, four ependymomas, one pineocytoma, three medulloblastomas, four acoustic nerve neurinomas, one intraspinal neurinoma, one neurofibroma, 10 meningiomas, and one craniopharyngioma) and three benign lesions of the nervous system were evaluated cytogenetically after in vitro culture. Sex chromosome loss was detected in 56% of the cases (-X in 13 of the 25 female patients and -Y in nine of the 16 male patients). The objective of the present report was to study the role of this abnormality in cells of the nervous system.Departamento de Genetica Instituto de Biociencias Universidade Estadual Paulista, 18618-000 Botucatu, SPDepartamento de Genetica Instituto de Biociencias Universidade Estadual Paulista, 18618-000 Botucatu, SPUniversidade Estadual Paulista (UNESP)Rogatto, S. R. [UNESP]Rainho, C. A. [UNESP]Neto, J. B. [UNESP]Casartelli, C. [UNESP]2022-04-28T19:54:00Z2022-04-28T19:54:00Z1994-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article215-222Brazilian Journal of Genetics, v. 17, n. 2, p. 215-222, 1994.0100-8455http://hdl.handle.net/11449/2239742-s2.0-0027993880Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Geneticsinfo:eu-repo/semantics/openAccess2022-04-28T19:54:00Zoai:repositorio.unesp.br:11449/223974Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:47:56.698344Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Loss of the sex chromosome in human neoplasias of the nervous system |
title |
Loss of the sex chromosome in human neoplasias of the nervous system |
spellingShingle |
Loss of the sex chromosome in human neoplasias of the nervous system Rogatto, S. R. [UNESP] |
title_short |
Loss of the sex chromosome in human neoplasias of the nervous system |
title_full |
Loss of the sex chromosome in human neoplasias of the nervous system |
title_fullStr |
Loss of the sex chromosome in human neoplasias of the nervous system |
title_full_unstemmed |
Loss of the sex chromosome in human neoplasias of the nervous system |
title_sort |
Loss of the sex chromosome in human neoplasias of the nervous system |
author |
Rogatto, S. R. [UNESP] |
author_facet |
Rogatto, S. R. [UNESP] Rainho, C. A. [UNESP] Neto, J. B. [UNESP] Casartelli, C. [UNESP] |
author_role |
author |
author2 |
Rainho, C. A. [UNESP] Neto, J. B. [UNESP] Casartelli, C. [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Rogatto, S. R. [UNESP] Rainho, C. A. [UNESP] Neto, J. B. [UNESP] Casartelli, C. [UNESP] |
description |
Thirty-eight tumors (five grade I-II astrocytomas, three grade III astrocytomas, four glioblastomas, one oligodendroglioma, four ependymomas, one pineocytoma, three medulloblastomas, four acoustic nerve neurinomas, one intraspinal neurinoma, one neurofibroma, 10 meningiomas, and one craniopharyngioma) and three benign lesions of the nervous system were evaluated cytogenetically after in vitro culture. Sex chromosome loss was detected in 56% of the cases (-X in 13 of the 25 female patients and -Y in nine of the 16 male patients). The objective of the present report was to study the role of this abnormality in cells of the nervous system. |
publishDate |
1994 |
dc.date.none.fl_str_mv |
1994-01-01 2022-04-28T19:54:00Z 2022-04-28T19:54:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Brazilian Journal of Genetics, v. 17, n. 2, p. 215-222, 1994. 0100-8455 http://hdl.handle.net/11449/223974 2-s2.0-0027993880 |
identifier_str_mv |
Brazilian Journal of Genetics, v. 17, n. 2, p. 215-222, 1994. 0100-8455 2-s2.0-0027993880 |
url |
http://hdl.handle.net/11449/223974 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Genetics |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
215-222 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129553235705856 |