Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition

Detalhes bibliográficos
Autor(a) principal: Garcia, Cindy Ruiz
Data de Publicação: 2022
Outros Autores: Ueda, Thaís Yumi, da Silva, Rafaela Alves, Cano, Isadora Prado, Saldanha, Luiz Leonardo [UNESP], Dokkedal, Anne Lígia [UNESP], Porto, Vinicius Carvalho, Urban, Vanessa Migliorini, Neppelenbroek, Karin Hermana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
DOI: 10.4155/tde-2021-0074
Texto Completo: http://dx.doi.org/10.4155/tde-2021-0074
http://hdl.handle.net/11449/223548
Resumo: Aim: This study investigated the effect of denture liners surface modification with Equisetum giganteum (EG) and Punica granatum (PG) on Candida albicans biofilm inhibition supposing its usage as a sustained-release therapeutical delivery system for Candida-associated denture stomatitis. Materials & methods:C. albicans biofilm (SC5314 or ATCC 90028) was formed on soft liners superficially modified by a primer mixed to drugs at minimum inhibitory concentrations (0.100 g for EG and PG or 0.016 g for nystatin per ml of primer). After 24 h, 7 or 14 days, antibiofilm activity was evaluated by colony-forming unit counts. Results: Not all groups were equi-efficient to nystatin after 24 h and 7 days. After 14 days, EG and PG efficacies were not different from nystatin (almost 100% inhibition). Conclusion: The proposed protocol presents a promising option to allopathic drugs for Candida-associated denture stomatitis treatment.
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spelling Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibitionantimicrobial agentsCandida albicansdenture linersdenture stomatitisnatural productsAim: This study investigated the effect of denture liners surface modification with Equisetum giganteum (EG) and Punica granatum (PG) on Candida albicans biofilm inhibition supposing its usage as a sustained-release therapeutical delivery system for Candida-associated denture stomatitis. Materials & methods:C. albicans biofilm (SC5314 or ATCC 90028) was formed on soft liners superficially modified by a primer mixed to drugs at minimum inhibitory concentrations (0.100 g for EG and PG or 0.016 g for nystatin per ml of primer). After 24 h, 7 or 14 days, antibiofilm activity was evaluated by colony-forming unit counts. Results: Not all groups were equi-efficient to nystatin after 24 h and 7 days. After 14 days, EG and PG efficacies were not different from nystatin (almost 100% inhibition). Conclusion: The proposed protocol presents a promising option to allopathic drugs for Candida-associated denture stomatitis treatment.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Prosthodontics & Periodontics Bauru School of Dentistry University of São Paulo (USP)Department of Surgery Stomatology Pathology & Radiology Bauru School of Dentistry University of São Paulo (USP)Department of Biological Sciences São Paulo State University (UNESP)Department of Dentistry State University of Ponta Grossa (UEPG) PRDepartment of Biological Sciences São Paulo State University (UNESP)FAPESP: 2016/08702-2, 2017/07314-1Universidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)Universidade Estadual de Ponta Grossa (UEPG)Garcia, Cindy RuizUeda, Thaís Yumida Silva, Rafaela AlvesCano, Isadora PradoSaldanha, Luiz Leonardo [UNESP]Dokkedal, Anne Lígia [UNESP]Porto, Vinicius CarvalhoUrban, Vanessa MiglioriniNeppelenbroek, Karin Hermana2022-04-28T19:51:22Z2022-04-28T19:51:22Z2022-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article157-166http://dx.doi.org/10.4155/tde-2021-0074Therapeutic delivery, v. 13, n. 3, p. 157-166, 2022.2041-6008http://hdl.handle.net/11449/22354810.4155/tde-2021-00742-s2.0-85125553897Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengTherapeutic deliveryinfo:eu-repo/semantics/openAccess2022-04-28T19:51:22Zoai:repositorio.unesp.br:11449/223548Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:18:58.123753Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
title Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
spellingShingle Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
Garcia, Cindy Ruiz
antimicrobial agents
Candida albicans
denture liners
denture stomatitis
natural products
Garcia, Cindy Ruiz
antimicrobial agents
Candida albicans
denture liners
denture stomatitis
natural products
title_short Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
title_full Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
title_fullStr Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
title_full_unstemmed Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
title_sort Effect of denture liners surface modification with Equisetum giganteum and Punica granatum on Candida albicans biofilm inhibition
author Garcia, Cindy Ruiz
author_facet Garcia, Cindy Ruiz
Garcia, Cindy Ruiz
Ueda, Thaís Yumi
da Silva, Rafaela Alves
Cano, Isadora Prado
Saldanha, Luiz Leonardo [UNESP]
Dokkedal, Anne Lígia [UNESP]
Porto, Vinicius Carvalho
Urban, Vanessa Migliorini
Neppelenbroek, Karin Hermana
Ueda, Thaís Yumi
da Silva, Rafaela Alves
Cano, Isadora Prado
Saldanha, Luiz Leonardo [UNESP]
Dokkedal, Anne Lígia [UNESP]
Porto, Vinicius Carvalho
Urban, Vanessa Migliorini
Neppelenbroek, Karin Hermana
author_role author
author2 Ueda, Thaís Yumi
da Silva, Rafaela Alves
Cano, Isadora Prado
Saldanha, Luiz Leonardo [UNESP]
Dokkedal, Anne Lígia [UNESP]
Porto, Vinicius Carvalho
Urban, Vanessa Migliorini
Neppelenbroek, Karin Hermana
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Estadual Paulista (UNESP)
Universidade Estadual de Ponta Grossa (UEPG)
dc.contributor.author.fl_str_mv Garcia, Cindy Ruiz
Ueda, Thaís Yumi
da Silva, Rafaela Alves
Cano, Isadora Prado
Saldanha, Luiz Leonardo [UNESP]
Dokkedal, Anne Lígia [UNESP]
Porto, Vinicius Carvalho
Urban, Vanessa Migliorini
Neppelenbroek, Karin Hermana
dc.subject.por.fl_str_mv antimicrobial agents
Candida albicans
denture liners
denture stomatitis
natural products
topic antimicrobial agents
Candida albicans
denture liners
denture stomatitis
natural products
description Aim: This study investigated the effect of denture liners surface modification with Equisetum giganteum (EG) and Punica granatum (PG) on Candida albicans biofilm inhibition supposing its usage as a sustained-release therapeutical delivery system for Candida-associated denture stomatitis. Materials & methods:C. albicans biofilm (SC5314 or ATCC 90028) was formed on soft liners superficially modified by a primer mixed to drugs at minimum inhibitory concentrations (0.100 g for EG and PG or 0.016 g for nystatin per ml of primer). After 24 h, 7 or 14 days, antibiofilm activity was evaluated by colony-forming unit counts. Results: Not all groups were equi-efficient to nystatin after 24 h and 7 days. After 14 days, EG and PG efficacies were not different from nystatin (almost 100% inhibition). Conclusion: The proposed protocol presents a promising option to allopathic drugs for Candida-associated denture stomatitis treatment.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-28T19:51:22Z
2022-04-28T19:51:22Z
2022-03-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4155/tde-2021-0074
Therapeutic delivery, v. 13, n. 3, p. 157-166, 2022.
2041-6008
http://hdl.handle.net/11449/223548
10.4155/tde-2021-0074
2-s2.0-85125553897
url http://dx.doi.org/10.4155/tde-2021-0074
http://hdl.handle.net/11449/223548
identifier_str_mv Therapeutic delivery, v. 13, n. 3, p. 157-166, 2022.
2041-6008
10.4155/tde-2021-0074
2-s2.0-85125553897
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Therapeutic delivery
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 157-166
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1822182483820544000
dc.identifier.doi.none.fl_str_mv 10.4155/tde-2021-0074

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