Craniofacial Features in Richieri-Costa-Pereira Syndrome

Detalhes bibliográficos
Autor(a) principal: Pardo, Milena P.
Data de Publicação: 2021
Outros Autores: Santos, Gabriela Lopes dos [UNESP], Carvalho, Izabel M.M., Tjioe, Kellen Cristine [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1177/1055665620987749
http://hdl.handle.net/11449/228900
Resumo: Objective: Patients with Richieri-Costa-Pereira syndrome (RCPS) present severe craniofacial alterations and frequently require orthodontic and surgical procedures. Thus, this study aims to describe the craniofacial relationships in patients with RCPS. Design: Panoramic radiographs and lateral cephalometric teleradiographs of 7 patients with RCPS and 7 age- and sex-matched nonsyndromic patients were analyzed. Cephalometric measurements were used to determine the size of apical bases, the relationship between them, the pattern of craniofacial growth, and the facial heights of the patients. Interobservers’ concordance was verified by intraclass coefficient. For comparison between the groups, paired t test was employed. P values <.05 indicated statistical significance. Results: Average age of patients with RCPS was 18.5 years. Six patients were female. All patients with RCPS had Pierre-Robin sequence while 2 also presented cleft mandible. Most patients with RCPS had missing lower central incisors (100%), lower lateral incisors (85.7%), lower second premolars (85.7%), and/or upper lateral incisors (57.1%). Concordance between observers was excellent for all cephalometric measurements (0.87-0.99). Patients with RCPS presented severe craniofacial alterations when compared to control group: sella–nasion–B point (SNB) angle (73.8o ± 4.86o vs 78.85o ± 4.53o, P =.029), maxillary length (7.89 cm ± 0.58 cm vs 16.36 cm ± 0.75 cm, P =.001), mandibular length (9.90 cm ± 0.46 cm vs 20.61 cm ± 0.45 cm, P =.001), upper anterior face height (5.41 cm ± 0.50 cm vs 9.40 cm ± 0.47 cm, P =.001), lower anterior face height (5.48 cm ± 0.75 cm vs 11.66 cm ± 0.55 cm, P =.001), and posterior face height (6.70 cm ± 0.33 cm vs 13.65 cm ± 1.06 cm, P =.001). There was no difference in SNB, A point–nasion–B point, pogonion–nasion–B point, and mandibular place angles between the groups (P >.05). Conclusion: Patients with RCPS present deficient development of maxilla and mandible when compared with nonsyndromic patients.
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spelling Craniofacial Features in Richieri-Costa-Pereira Syndromecephalometryorthodontic treatmentorthognathic surgeryPierre-Robin sequenceRichieri-Costa-Pereira syndromeObjective: Patients with Richieri-Costa-Pereira syndrome (RCPS) present severe craniofacial alterations and frequently require orthodontic and surgical procedures. Thus, this study aims to describe the craniofacial relationships in patients with RCPS. Design: Panoramic radiographs and lateral cephalometric teleradiographs of 7 patients with RCPS and 7 age- and sex-matched nonsyndromic patients were analyzed. Cephalometric measurements were used to determine the size of apical bases, the relationship between them, the pattern of craniofacial growth, and the facial heights of the patients. Interobservers’ concordance was verified by intraclass coefficient. For comparison between the groups, paired t test was employed. P values <.05 indicated statistical significance. Results: Average age of patients with RCPS was 18.5 years. Six patients were female. All patients with RCPS had Pierre-Robin sequence while 2 also presented cleft mandible. Most patients with RCPS had missing lower central incisors (100%), lower lateral incisors (85.7%), lower second premolars (85.7%), and/or upper lateral incisors (57.1%). Concordance between observers was excellent for all cephalometric measurements (0.87-0.99). Patients with RCPS presented severe craniofacial alterations when compared to control group: sella–nasion–B point (SNB) angle (73.8o ± 4.86o vs 78.85o ± 4.53o, P =.029), maxillary length (7.89 cm ± 0.58 cm vs 16.36 cm ± 0.75 cm, P =.001), mandibular length (9.90 cm ± 0.46 cm vs 20.61 cm ± 0.45 cm, P =.001), upper anterior face height (5.41 cm ± 0.50 cm vs 9.40 cm ± 0.47 cm, P =.001), lower anterior face height (5.48 cm ± 0.75 cm vs 11.66 cm ± 0.55 cm, P =.001), and posterior face height (6.70 cm ± 0.33 cm vs 13.65 cm ± 1.06 cm, P =.001). There was no difference in SNB, A point–nasion–B point, pogonion–nasion–B point, and mandibular place angles between the groups (P >.05). Conclusion: Patients with RCPS present deficient development of maxilla and mandible when compared with nonsyndromic patients.Hospital for Rehabilitation of Craniofacial Anomalies University of São Paulo, Rua Silvio MarchioneOral Oncology Center São Paulo State University, Rua Jose BonifácioOral Oncology Center São Paulo State University, Rua Jose BonifácioUniversidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)Pardo, Milena P.Santos, Gabriela Lopes dos [UNESP]Carvalho, Izabel M.M.Tjioe, Kellen Cristine [UNESP]2022-04-29T08:29:11Z2022-04-29T08:29:11Z2021-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1370-1375http://dx.doi.org/10.1177/1055665620987749Cleft Palate-Craniofacial Journal, v. 58, n. 11, p. 1370-1375, 2021.1545-15691055-6656http://hdl.handle.net/11449/22890010.1177/10556656209877492-s2.0-85100544567Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCleft Palate-Craniofacial Journalinfo:eu-repo/semantics/openAccess2024-04-11T20:16:33Zoai:repositorio.unesp.br:11449/228900Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:40:09.508212Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Craniofacial Features in Richieri-Costa-Pereira Syndrome
title Craniofacial Features in Richieri-Costa-Pereira Syndrome
spellingShingle Craniofacial Features in Richieri-Costa-Pereira Syndrome
Pardo, Milena P.
cephalometry
orthodontic treatment
orthognathic surgery
Pierre-Robin sequence
Richieri-Costa-Pereira syndrome
title_short Craniofacial Features in Richieri-Costa-Pereira Syndrome
title_full Craniofacial Features in Richieri-Costa-Pereira Syndrome
title_fullStr Craniofacial Features in Richieri-Costa-Pereira Syndrome
title_full_unstemmed Craniofacial Features in Richieri-Costa-Pereira Syndrome
title_sort Craniofacial Features in Richieri-Costa-Pereira Syndrome
author Pardo, Milena P.
author_facet Pardo, Milena P.
Santos, Gabriela Lopes dos [UNESP]
Carvalho, Izabel M.M.
Tjioe, Kellen Cristine [UNESP]
author_role author
author2 Santos, Gabriela Lopes dos [UNESP]
Carvalho, Izabel M.M.
Tjioe, Kellen Cristine [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Pardo, Milena P.
Santos, Gabriela Lopes dos [UNESP]
Carvalho, Izabel M.M.
Tjioe, Kellen Cristine [UNESP]
dc.subject.por.fl_str_mv cephalometry
orthodontic treatment
orthognathic surgery
Pierre-Robin sequence
Richieri-Costa-Pereira syndrome
topic cephalometry
orthodontic treatment
orthognathic surgery
Pierre-Robin sequence
Richieri-Costa-Pereira syndrome
description Objective: Patients with Richieri-Costa-Pereira syndrome (RCPS) present severe craniofacial alterations and frequently require orthodontic and surgical procedures. Thus, this study aims to describe the craniofacial relationships in patients with RCPS. Design: Panoramic radiographs and lateral cephalometric teleradiographs of 7 patients with RCPS and 7 age- and sex-matched nonsyndromic patients were analyzed. Cephalometric measurements were used to determine the size of apical bases, the relationship between them, the pattern of craniofacial growth, and the facial heights of the patients. Interobservers’ concordance was verified by intraclass coefficient. For comparison between the groups, paired t test was employed. P values <.05 indicated statistical significance. Results: Average age of patients with RCPS was 18.5 years. Six patients were female. All patients with RCPS had Pierre-Robin sequence while 2 also presented cleft mandible. Most patients with RCPS had missing lower central incisors (100%), lower lateral incisors (85.7%), lower second premolars (85.7%), and/or upper lateral incisors (57.1%). Concordance between observers was excellent for all cephalometric measurements (0.87-0.99). Patients with RCPS presented severe craniofacial alterations when compared to control group: sella–nasion–B point (SNB) angle (73.8o ± 4.86o vs 78.85o ± 4.53o, P =.029), maxillary length (7.89 cm ± 0.58 cm vs 16.36 cm ± 0.75 cm, P =.001), mandibular length (9.90 cm ± 0.46 cm vs 20.61 cm ± 0.45 cm, P =.001), upper anterior face height (5.41 cm ± 0.50 cm vs 9.40 cm ± 0.47 cm, P =.001), lower anterior face height (5.48 cm ± 0.75 cm vs 11.66 cm ± 0.55 cm, P =.001), and posterior face height (6.70 cm ± 0.33 cm vs 13.65 cm ± 1.06 cm, P =.001). There was no difference in SNB, A point–nasion–B point, pogonion–nasion–B point, and mandibular place angles between the groups (P >.05). Conclusion: Patients with RCPS present deficient development of maxilla and mandible when compared with nonsyndromic patients.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-01
2022-04-29T08:29:11Z
2022-04-29T08:29:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1177/1055665620987749
Cleft Palate-Craniofacial Journal, v. 58, n. 11, p. 1370-1375, 2021.
1545-1569
1055-6656
http://hdl.handle.net/11449/228900
10.1177/1055665620987749
2-s2.0-85100544567
url http://dx.doi.org/10.1177/1055665620987749
http://hdl.handle.net/11449/228900
identifier_str_mv Cleft Palate-Craniofacial Journal, v. 58, n. 11, p. 1370-1375, 2021.
1545-1569
1055-6656
10.1177/1055665620987749
2-s2.0-85100544567
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Cleft Palate-Craniofacial Journal
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1370-1375
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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