Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa

Detalhes bibliográficos
Autor(a) principal: Dias, Flávia Neves Bueloni [UNESP]
Data de Publicação: 2014
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/113899
Resumo: Objective: To evaluate the clinical predictive factors of endometrial polyps in postmenopausal women. Methods: In this clinical, analytical, comparative and cross-sectional study 132 patients with histopathologic diagnosis of endometrial polyp were compared with 264 without endometrial alterations (control), seeking healthcare at a Public University Hospital. In the study were included women with amenorrhea ≥ 12 months and age ≥ 45 years, in a proportion of 1 case to 2 controls. Clinical, anthropometric, laboratory and ultrasonographic data were collected for evaluating the predictive factors of endometrial polyps. For statistical analysis were used the Student-t, chi-square tests and logistic regression method (odds ratio-OR). Results: Patients with endometrial polyps were older and had more time since menopause when compared to control (P <.0001). A higher percentage of women with endometrial polyps were obese (72%) compared to control (39%) (P <.0001). The measurement of waist circumference was higher among patients with polyps (P = 0.0001). We observed a higher incidence of diabetes, hypertension and dyslipidemia in patients with endometrial polyps (P <.0001). According to the NCEP/ATP III, 48.5% of women with polyps and 33.3% in the control group were classified as having metabolic syndrome (P = 0.004). Analysis of risk for endometrial polyp formation was higher in patients with: BMI ≥ 25 kg/m2 (OR 4.66; CI 95% 2.16-10.05); glucose ≥ 100 mg/dl (OR 2.83; CI 95% 1.36-5.90); dyslipidemia (OR 7.02; CI 95% 3.70-13.32); diabetes (OR 2.58; CI 95% 1.05-6.32); and metabolic syndrome (OR 2.76; CI 95% 1.18-6.46). (P = 0.019) compared to control. Conclusion: In postmenopausal women, obesity, dyslipidemia, hyperglycemia and the presence of metabolic syndrome were predictive factors for endometrial polyp
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spelling Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausaMulheresPós-menopausaEndometrioPóliposSíndrome metabólicaEndometriumObjective: To evaluate the clinical predictive factors of endometrial polyps in postmenopausal women. Methods: In this clinical, analytical, comparative and cross-sectional study 132 patients with histopathologic diagnosis of endometrial polyp were compared with 264 without endometrial alterations (control), seeking healthcare at a Public University Hospital. In the study were included women with amenorrhea ≥ 12 months and age ≥ 45 years, in a proportion of 1 case to 2 controls. Clinical, anthropometric, laboratory and ultrasonographic data were collected for evaluating the predictive factors of endometrial polyps. For statistical analysis were used the Student-t, chi-square tests and logistic regression method (odds ratio-OR). Results: Patients with endometrial polyps were older and had more time since menopause when compared to control (P <.0001). A higher percentage of women with endometrial polyps were obese (72%) compared to control (39%) (P <.0001). The measurement of waist circumference was higher among patients with polyps (P = 0.0001). We observed a higher incidence of diabetes, hypertension and dyslipidemia in patients with endometrial polyps (P <.0001). According to the NCEP/ATP III, 48.5% of women with polyps and 33.3% in the control group were classified as having metabolic syndrome (P = 0.004). Analysis of risk for endometrial polyp formation was higher in patients with: BMI ≥ 25 kg/m2 (OR 4.66; CI 95% 2.16-10.05); glucose ≥ 100 mg/dl (OR 2.83; CI 95% 1.36-5.90); dyslipidemia (OR 7.02; CI 95% 3.70-13.32); diabetes (OR 2.58; CI 95% 1.05-6.32); and metabolic syndrome (OR 2.76; CI 95% 1.18-6.46). (P = 0.019) compared to control. Conclusion: In postmenopausal women, obesity, dyslipidemia, hyperglycemia and the presence of metabolic syndrome were predictive factors for endometrial polypAvaliar os fatores clínicos preditivos para o desenvolvimento dos pólipos endometriais em mulheres na pós-menopausa. Métodos: Foi conduzido ensaio clínico, analítico, comparativo e transversal, envolvendo mulheres na pós-menopausa, 132 com diagnóstico anatomopatológico de pólipo endometrial e 264 sem alterações endometriais, atendidas em Hospital Público Universitário. Foram incluídas no estudo mulheres com amenorréia ≥ 12 meses e idade ≥ 45 anos, em uma proporção de 1 caso para 2 controles. Foram coletados dados clínicos, antropométricos, laboratoriais e ultrassonográficos, para avaliação dos fatores preditivos do pólipo endometrial. Para análise estatística empregou-se os testes t-Student, Qui-Quadrado e Regressão Logística (OR, odds ratio). Resultados: As pacientes com pólipo endometrial apresentaram idade mais avançada e maior tempo de menopausa quando comparadas ao controle (P<0,0001). Maior porcentagem de mulheres com pólipo era obesa (72%) quando comparadas ao controle (39%) (P<0,0001). A medida da circunferência da cintura foi maior entre as pacientes com pólipo (P=0,0001). Observou-se maior incidência de diabetes, hipertensão e dislipidemias nas pacientes com pólipo endometrial (P<0,0001). De acordo com os critérios do NCEP/ATP III, 48,5% das mulheres com pólipo e 33,3% do grupo controle foram classificadas como portadoras da síndrome metabólica (P=0,004). Em relação ao grupo controle, apresentaram maior chance de desenvolvimento de pólipo endometrial às pacientes com: IMC ≥ 25 kg/m2 (OR 4,66; IC 95% 2,16-10,05); glicose ≥ 100 mg/dl (OR 2,83; IC 95% 1,36-5,90); dislipidemia (OR 7,02; IC 95% 3,70-13,32), diabetes (OR 2,58; IC 95% 1,05-6,32); e síndrome metabólica (OR 2,76; IC 95% 1,18-6,46). Conclusão: Em mulheres na pós-menopausa, a obesidade, a dislipidemia, a hiperglicemia e a presença de síndrome metabólica foram fatores preditivos para o desenvolvimento de pólipo endometrialUniversidade Estadual Paulista (Unesp)Nahás, Eliana Aguiar Petri [UNESP]Nahas Neto, Jorge [UNESP]Universidade Estadual Paulista (Unesp)Dias, Flávia Neves Bueloni [UNESP]2015-01-26T13:21:21Z2015-01-26T13:21:21Z2014-08-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis58 f.application/pdfDIAS, Flávia Neves Bueloni. Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa. 2014. 58 f. Dissertação (mestrado) - Universidade Estadual Paulista JÚlio de Mesquita Filho, Faculdade de Medicina de Botucatu, 2014.http://hdl.handle.net/11449/113899000797758000797758.pdf33004064077P24155170574788417Alephreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporinfo:eu-repo/semantics/openAccess2024-09-03T18:30:18Zoai:repositorio.unesp.br:11449/113899Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-03T18:30:18Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa
title Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa
spellingShingle Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa
Dias, Flávia Neves Bueloni [UNESP]
Mulheres
Pós-menopausa
Endometrio
Pólipos
Síndrome metabólica
Endometrium
title_short Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa
title_full Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa
title_fullStr Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa
title_full_unstemmed Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa
title_sort Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa
author Dias, Flávia Neves Bueloni [UNESP]
author_facet Dias, Flávia Neves Bueloni [UNESP]
author_role author
dc.contributor.none.fl_str_mv Nahás, Eliana Aguiar Petri [UNESP]
Nahas Neto, Jorge [UNESP]
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Dias, Flávia Neves Bueloni [UNESP]
dc.subject.por.fl_str_mv Mulheres
Pós-menopausa
Endometrio
Pólipos
Síndrome metabólica
Endometrium
topic Mulheres
Pós-menopausa
Endometrio
Pólipos
Síndrome metabólica
Endometrium
description Objective: To evaluate the clinical predictive factors of endometrial polyps in postmenopausal women. Methods: In this clinical, analytical, comparative and cross-sectional study 132 patients with histopathologic diagnosis of endometrial polyp were compared with 264 without endometrial alterations (control), seeking healthcare at a Public University Hospital. In the study were included women with amenorrhea ≥ 12 months and age ≥ 45 years, in a proportion of 1 case to 2 controls. Clinical, anthropometric, laboratory and ultrasonographic data were collected for evaluating the predictive factors of endometrial polyps. For statistical analysis were used the Student-t, chi-square tests and logistic regression method (odds ratio-OR). Results: Patients with endometrial polyps were older and had more time since menopause when compared to control (P <.0001). A higher percentage of women with endometrial polyps were obese (72%) compared to control (39%) (P <.0001). The measurement of waist circumference was higher among patients with polyps (P = 0.0001). We observed a higher incidence of diabetes, hypertension and dyslipidemia in patients with endometrial polyps (P <.0001). According to the NCEP/ATP III, 48.5% of women with polyps and 33.3% in the control group were classified as having metabolic syndrome (P = 0.004). Analysis of risk for endometrial polyp formation was higher in patients with: BMI ≥ 25 kg/m2 (OR 4.66; CI 95% 2.16-10.05); glucose ≥ 100 mg/dl (OR 2.83; CI 95% 1.36-5.90); dyslipidemia (OR 7.02; CI 95% 3.70-13.32); diabetes (OR 2.58; CI 95% 1.05-6.32); and metabolic syndrome (OR 2.76; CI 95% 1.18-6.46). (P = 0.019) compared to control. Conclusion: In postmenopausal women, obesity, dyslipidemia, hyperglycemia and the presence of metabolic syndrome were predictive factors for endometrial polyp
publishDate 2014
dc.date.none.fl_str_mv 2014-08-15
2015-01-26T13:21:21Z
2015-01-26T13:21:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv DIAS, Flávia Neves Bueloni. Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa. 2014. 58 f. Dissertação (mestrado) - Universidade Estadual Paulista JÚlio de Mesquita Filho, Faculdade de Medicina de Botucatu, 2014.
http://hdl.handle.net/11449/113899
000797758
000797758.pdf
33004064077P2
4155170574788417
identifier_str_mv DIAS, Flávia Neves Bueloni. Avaliação dos fatores preditivos dos pólipos endometriais em mulheres na pós-menopausa. 2014. 58 f. Dissertação (mestrado) - Universidade Estadual Paulista JÚlio de Mesquita Filho, Faculdade de Medicina de Botucatu, 2014.
000797758
000797758.pdf
33004064077P2
4155170574788417
url http://hdl.handle.net/11449/113899
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 58 f.
application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual Paulista (Unesp)
publisher.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.source.none.fl_str_mv Aleph
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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