Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil

Detalhes bibliográficos
Autor(a) principal: Ferreira, Maria Izabela [UNESP]
Data de Publicação: 2017
Outros Autores: Magro, Massimiliano, Ming, Lin Chau [UNESP], da Silva, Monica Bartira [UNESP], Ormond Sobreira Rodrigues, Luan Fernando [UNESP], Zanoni do Prado, Débora [UNESP], Bonaiuto, Emanuela, Baratella, Davide, De Almeida Roger, Jessica, Pace Pereira Lima, Giuseppina [UNESP], Rossetto, Monica, Zennaro, Lucio, Vianello, Fabio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.jclepro.2017.03.218
http://hdl.handle.net/11449/178838
Resumo: Large volumes of residual biomass could represent a matter of concern for large-scale purification of natural compounds, heavily influencing processing industries and logistic sizing, amount of solvents employed for the extraction processes and the final chemical and biological waste generation. In the present study, carried out in Brazil, the production of curcuminoids in Curcuma longa L. rhizomes was maximized as a function of plant maturity and solar UV exclusion. Noteworthy, curcuminoid content reached its maximum at around the end of the early vegetative phase (65 days after planting), henceforward plant growth determined only a detrimental accumulation of wastes. The harvesting at this early phase of plant maturation led to a more than tenfold reduction of exceeding biomass. In addition, by means of an innovative, sustainable and high efficient magnetic purification process for curcuminoids based on Surface Active Maghemite Nanoparticles (SAMNs), an outstanding yield of 90% and >98% purity, were achieved in a single magnetic purification step. The formation of the SAMN-curcuminoid complex (SAMN@curcuminoid) was demonstrated by optical and electron spin resonance spectroscopy and electron microscopy. The scalability of the purification method was proved by the application of an automatic modular pilot system for continuous magnetic purification of curcuminoids, capable of managing 100 L day−1 of SAMN@curcuminoid suspensions. The presented multidisciplinary approach embodies the fundamental principles of cleaner production providing a paradigm for the utilization of magnetic nanoparticles for biomolecule purification. Moreover, Brazilian agro-industries can benefit from sustainable innovation strategy outlined by the current study.
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spelling Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in BrazilBiomass reductionCurcumin productionCurcumin purificationMagnetic nanoparticlesMagnetic purificationTurmericLarge volumes of residual biomass could represent a matter of concern for large-scale purification of natural compounds, heavily influencing processing industries and logistic sizing, amount of solvents employed for the extraction processes and the final chemical and biological waste generation. In the present study, carried out in Brazil, the production of curcuminoids in Curcuma longa L. rhizomes was maximized as a function of plant maturity and solar UV exclusion. Noteworthy, curcuminoid content reached its maximum at around the end of the early vegetative phase (65 days after planting), henceforward plant growth determined only a detrimental accumulation of wastes. The harvesting at this early phase of plant maturation led to a more than tenfold reduction of exceeding biomass. In addition, by means of an innovative, sustainable and high efficient magnetic purification process for curcuminoids based on Surface Active Maghemite Nanoparticles (SAMNs), an outstanding yield of 90% and >98% purity, were achieved in a single magnetic purification step. The formation of the SAMN-curcuminoid complex (SAMN@curcuminoid) was demonstrated by optical and electron spin resonance spectroscopy and electron microscopy. The scalability of the purification method was proved by the application of an automatic modular pilot system for continuous magnetic purification of curcuminoids, capable of managing 100 L day−1 of SAMN@curcuminoid suspensions. The presented multidisciplinary approach embodies the fundamental principles of cleaner production providing a paradigm for the utilization of magnetic nanoparticles for biomolecule purification. Moreover, Brazilian agro-industries can benefit from sustainable innovation strategy outlined by the current study.Department of Chemistry and Biochemistry São Paulo State University (UNESP) Institute of Biosciences, São Paulo, CP 510Department of Comparative Biomedicine and Food Science University of PaduaRegional Centre of Advanced Technologies and Materials Department of Physical Chemistry and Experimental Physics Faculty of Science Palacky University, 17 Listopadu 1192/12Department of Horticulture São Paulo State University (UNESP) School of Agriculture, São Paulo, CP 510Department of Molecular Medicine University of PaduaDepartment of Chemistry and Biochemistry São Paulo State University (UNESP) Institute of Biosciences, São Paulo, CP 510Department of Horticulture São Paulo State University (UNESP) School of Agriculture, São Paulo, CP 510Universidade Estadual Paulista (Unesp)University of PaduaPalacky UniversityFerreira, Maria Izabela [UNESP]Magro, MassimilianoMing, Lin Chau [UNESP]da Silva, Monica Bartira [UNESP]Ormond Sobreira Rodrigues, Luan Fernando [UNESP]Zanoni do Prado, Débora [UNESP]Bonaiuto, EmanuelaBaratella, DavideDe Almeida Roger, JessicaPace Pereira Lima, Giuseppina [UNESP]Rossetto, MonicaZennaro, LucioVianello, Fabio2018-12-11T17:32:18Z2018-12-11T17:32:18Z2017-06-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article233-241application/pdfhttp://dx.doi.org/10.1016/j.jclepro.2017.03.218Journal of Cleaner Production, v. 154, p. 233-241.0959-6526http://hdl.handle.net/11449/17883810.1016/j.jclepro.2017.03.2182-s2.0-850185867302-s2.0-85018586730.pdf4390073683610512Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Cleaner Production1,467info:eu-repo/semantics/openAccess2024-04-30T14:34:10Zoai:repositorio.unesp.br:11449/178838Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:51:25.329827Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil
title Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil
spellingShingle Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil
Ferreira, Maria Izabela [UNESP]
Biomass reduction
Curcumin production
Curcumin purification
Magnetic nanoparticles
Magnetic purification
Turmeric
title_short Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil
title_full Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil
title_fullStr Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil
title_full_unstemmed Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil
title_sort Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil
author Ferreira, Maria Izabela [UNESP]
author_facet Ferreira, Maria Izabela [UNESP]
Magro, Massimiliano
Ming, Lin Chau [UNESP]
da Silva, Monica Bartira [UNESP]
Ormond Sobreira Rodrigues, Luan Fernando [UNESP]
Zanoni do Prado, Débora [UNESP]
Bonaiuto, Emanuela
Baratella, Davide
De Almeida Roger, Jessica
Pace Pereira Lima, Giuseppina [UNESP]
Rossetto, Monica
Zennaro, Lucio
Vianello, Fabio
author_role author
author2 Magro, Massimiliano
Ming, Lin Chau [UNESP]
da Silva, Monica Bartira [UNESP]
Ormond Sobreira Rodrigues, Luan Fernando [UNESP]
Zanoni do Prado, Débora [UNESP]
Bonaiuto, Emanuela
Baratella, Davide
De Almeida Roger, Jessica
Pace Pereira Lima, Giuseppina [UNESP]
Rossetto, Monica
Zennaro, Lucio
Vianello, Fabio
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
University of Padua
Palacky University
dc.contributor.author.fl_str_mv Ferreira, Maria Izabela [UNESP]
Magro, Massimiliano
Ming, Lin Chau [UNESP]
da Silva, Monica Bartira [UNESP]
Ormond Sobreira Rodrigues, Luan Fernando [UNESP]
Zanoni do Prado, Débora [UNESP]
Bonaiuto, Emanuela
Baratella, Davide
De Almeida Roger, Jessica
Pace Pereira Lima, Giuseppina [UNESP]
Rossetto, Monica
Zennaro, Lucio
Vianello, Fabio
dc.subject.por.fl_str_mv Biomass reduction
Curcumin production
Curcumin purification
Magnetic nanoparticles
Magnetic purification
Turmeric
topic Biomass reduction
Curcumin production
Curcumin purification
Magnetic nanoparticles
Magnetic purification
Turmeric
description Large volumes of residual biomass could represent a matter of concern for large-scale purification of natural compounds, heavily influencing processing industries and logistic sizing, amount of solvents employed for the extraction processes and the final chemical and biological waste generation. In the present study, carried out in Brazil, the production of curcuminoids in Curcuma longa L. rhizomes was maximized as a function of plant maturity and solar UV exclusion. Noteworthy, curcuminoid content reached its maximum at around the end of the early vegetative phase (65 days after planting), henceforward plant growth determined only a detrimental accumulation of wastes. The harvesting at this early phase of plant maturation led to a more than tenfold reduction of exceeding biomass. In addition, by means of an innovative, sustainable and high efficient magnetic purification process for curcuminoids based on Surface Active Maghemite Nanoparticles (SAMNs), an outstanding yield of 90% and >98% purity, were achieved in a single magnetic purification step. The formation of the SAMN-curcuminoid complex (SAMN@curcuminoid) was demonstrated by optical and electron spin resonance spectroscopy and electron microscopy. The scalability of the purification method was proved by the application of an automatic modular pilot system for continuous magnetic purification of curcuminoids, capable of managing 100 L day−1 of SAMN@curcuminoid suspensions. The presented multidisciplinary approach embodies the fundamental principles of cleaner production providing a paradigm for the utilization of magnetic nanoparticles for biomolecule purification. Moreover, Brazilian agro-industries can benefit from sustainable innovation strategy outlined by the current study.
publishDate 2017
dc.date.none.fl_str_mv 2017-06-15
2018-12-11T17:32:18Z
2018-12-11T17:32:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.jclepro.2017.03.218
Journal of Cleaner Production, v. 154, p. 233-241.
0959-6526
http://hdl.handle.net/11449/178838
10.1016/j.jclepro.2017.03.218
2-s2.0-85018586730
2-s2.0-85018586730.pdf
4390073683610512
url http://dx.doi.org/10.1016/j.jclepro.2017.03.218
http://hdl.handle.net/11449/178838
identifier_str_mv Journal of Cleaner Production, v. 154, p. 233-241.
0959-6526
10.1016/j.jclepro.2017.03.218
2-s2.0-85018586730
2-s2.0-85018586730.pdf
4390073683610512
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Cleaner Production
1,467
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 233-241
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
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instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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