Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.jclepro.2017.03.218 http://hdl.handle.net/11449/178838 |
Resumo: | Large volumes of residual biomass could represent a matter of concern for large-scale purification of natural compounds, heavily influencing processing industries and logistic sizing, amount of solvents employed for the extraction processes and the final chemical and biological waste generation. In the present study, carried out in Brazil, the production of curcuminoids in Curcuma longa L. rhizomes was maximized as a function of plant maturity and solar UV exclusion. Noteworthy, curcuminoid content reached its maximum at around the end of the early vegetative phase (65 days after planting), henceforward plant growth determined only a detrimental accumulation of wastes. The harvesting at this early phase of plant maturation led to a more than tenfold reduction of exceeding biomass. In addition, by means of an innovative, sustainable and high efficient magnetic purification process for curcuminoids based on Surface Active Maghemite Nanoparticles (SAMNs), an outstanding yield of 90% and >98% purity, were achieved in a single magnetic purification step. The formation of the SAMN-curcuminoid complex (SAMN@curcuminoid) was demonstrated by optical and electron spin resonance spectroscopy and electron microscopy. The scalability of the purification method was proved by the application of an automatic modular pilot system for continuous magnetic purification of curcuminoids, capable of managing 100 L day−1 of SAMN@curcuminoid suspensions. The presented multidisciplinary approach embodies the fundamental principles of cleaner production providing a paradigm for the utilization of magnetic nanoparticles for biomolecule purification. Moreover, Brazilian agro-industries can benefit from sustainable innovation strategy outlined by the current study. |
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Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in BrazilBiomass reductionCurcumin productionCurcumin purificationMagnetic nanoparticlesMagnetic purificationTurmericLarge volumes of residual biomass could represent a matter of concern for large-scale purification of natural compounds, heavily influencing processing industries and logistic sizing, amount of solvents employed for the extraction processes and the final chemical and biological waste generation. In the present study, carried out in Brazil, the production of curcuminoids in Curcuma longa L. rhizomes was maximized as a function of plant maturity and solar UV exclusion. Noteworthy, curcuminoid content reached its maximum at around the end of the early vegetative phase (65 days after planting), henceforward plant growth determined only a detrimental accumulation of wastes. The harvesting at this early phase of plant maturation led to a more than tenfold reduction of exceeding biomass. In addition, by means of an innovative, sustainable and high efficient magnetic purification process for curcuminoids based on Surface Active Maghemite Nanoparticles (SAMNs), an outstanding yield of 90% and >98% purity, were achieved in a single magnetic purification step. The formation of the SAMN-curcuminoid complex (SAMN@curcuminoid) was demonstrated by optical and electron spin resonance spectroscopy and electron microscopy. The scalability of the purification method was proved by the application of an automatic modular pilot system for continuous magnetic purification of curcuminoids, capable of managing 100 L day−1 of SAMN@curcuminoid suspensions. The presented multidisciplinary approach embodies the fundamental principles of cleaner production providing a paradigm for the utilization of magnetic nanoparticles for biomolecule purification. Moreover, Brazilian agro-industries can benefit from sustainable innovation strategy outlined by the current study.Department of Chemistry and Biochemistry São Paulo State University (UNESP) Institute of Biosciences, São Paulo, CP 510Department of Comparative Biomedicine and Food Science University of PaduaRegional Centre of Advanced Technologies and Materials Department of Physical Chemistry and Experimental Physics Faculty of Science Palacky University, 17 Listopadu 1192/12Department of Horticulture São Paulo State University (UNESP) School of Agriculture, São Paulo, CP 510Department of Molecular Medicine University of PaduaDepartment of Chemistry and Biochemistry São Paulo State University (UNESP) Institute of Biosciences, São Paulo, CP 510Department of Horticulture São Paulo State University (UNESP) School of Agriculture, São Paulo, CP 510Universidade Estadual Paulista (Unesp)University of PaduaPalacky UniversityFerreira, Maria Izabela [UNESP]Magro, MassimilianoMing, Lin Chau [UNESP]da Silva, Monica Bartira [UNESP]Ormond Sobreira Rodrigues, Luan Fernando [UNESP]Zanoni do Prado, Débora [UNESP]Bonaiuto, EmanuelaBaratella, DavideDe Almeida Roger, JessicaPace Pereira Lima, Giuseppina [UNESP]Rossetto, MonicaZennaro, LucioVianello, Fabio2018-12-11T17:32:18Z2018-12-11T17:32:18Z2017-06-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article233-241application/pdfhttp://dx.doi.org/10.1016/j.jclepro.2017.03.218Journal of Cleaner Production, v. 154, p. 233-241.0959-6526http://hdl.handle.net/11449/17883810.1016/j.jclepro.2017.03.2182-s2.0-850185867302-s2.0-85018586730.pdf4390073683610512Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Cleaner Production1,467info:eu-repo/semantics/openAccess2024-04-30T14:34:10Zoai:repositorio.unesp.br:11449/178838Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:51:25.329827Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil |
title |
Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil |
spellingShingle |
Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil Ferreira, Maria Izabela [UNESP] Biomass reduction Curcumin production Curcumin purification Magnetic nanoparticles Magnetic purification Turmeric |
title_short |
Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil |
title_full |
Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil |
title_fullStr |
Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil |
title_full_unstemmed |
Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil |
title_sort |
Sustainable production of high purity curcuminoids from Curcuma longa by magnetic nanoparticles: A case study in Brazil |
author |
Ferreira, Maria Izabela [UNESP] |
author_facet |
Ferreira, Maria Izabela [UNESP] Magro, Massimiliano Ming, Lin Chau [UNESP] da Silva, Monica Bartira [UNESP] Ormond Sobreira Rodrigues, Luan Fernando [UNESP] Zanoni do Prado, Débora [UNESP] Bonaiuto, Emanuela Baratella, Davide De Almeida Roger, Jessica Pace Pereira Lima, Giuseppina [UNESP] Rossetto, Monica Zennaro, Lucio Vianello, Fabio |
author_role |
author |
author2 |
Magro, Massimiliano Ming, Lin Chau [UNESP] da Silva, Monica Bartira [UNESP] Ormond Sobreira Rodrigues, Luan Fernando [UNESP] Zanoni do Prado, Débora [UNESP] Bonaiuto, Emanuela Baratella, Davide De Almeida Roger, Jessica Pace Pereira Lima, Giuseppina [UNESP] Rossetto, Monica Zennaro, Lucio Vianello, Fabio |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) University of Padua Palacky University |
dc.contributor.author.fl_str_mv |
Ferreira, Maria Izabela [UNESP] Magro, Massimiliano Ming, Lin Chau [UNESP] da Silva, Monica Bartira [UNESP] Ormond Sobreira Rodrigues, Luan Fernando [UNESP] Zanoni do Prado, Débora [UNESP] Bonaiuto, Emanuela Baratella, Davide De Almeida Roger, Jessica Pace Pereira Lima, Giuseppina [UNESP] Rossetto, Monica Zennaro, Lucio Vianello, Fabio |
dc.subject.por.fl_str_mv |
Biomass reduction Curcumin production Curcumin purification Magnetic nanoparticles Magnetic purification Turmeric |
topic |
Biomass reduction Curcumin production Curcumin purification Magnetic nanoparticles Magnetic purification Turmeric |
description |
Large volumes of residual biomass could represent a matter of concern for large-scale purification of natural compounds, heavily influencing processing industries and logistic sizing, amount of solvents employed for the extraction processes and the final chemical and biological waste generation. In the present study, carried out in Brazil, the production of curcuminoids in Curcuma longa L. rhizomes was maximized as a function of plant maturity and solar UV exclusion. Noteworthy, curcuminoid content reached its maximum at around the end of the early vegetative phase (65 days after planting), henceforward plant growth determined only a detrimental accumulation of wastes. The harvesting at this early phase of plant maturation led to a more than tenfold reduction of exceeding biomass. In addition, by means of an innovative, sustainable and high efficient magnetic purification process for curcuminoids based on Surface Active Maghemite Nanoparticles (SAMNs), an outstanding yield of 90% and >98% purity, were achieved in a single magnetic purification step. The formation of the SAMN-curcuminoid complex (SAMN@curcuminoid) was demonstrated by optical and electron spin resonance spectroscopy and electron microscopy. The scalability of the purification method was proved by the application of an automatic modular pilot system for continuous magnetic purification of curcuminoids, capable of managing 100 L day−1 of SAMN@curcuminoid suspensions. The presented multidisciplinary approach embodies the fundamental principles of cleaner production providing a paradigm for the utilization of magnetic nanoparticles for biomolecule purification. Moreover, Brazilian agro-industries can benefit from sustainable innovation strategy outlined by the current study. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-06-15 2018-12-11T17:32:18Z 2018-12-11T17:32:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.jclepro.2017.03.218 Journal of Cleaner Production, v. 154, p. 233-241. 0959-6526 http://hdl.handle.net/11449/178838 10.1016/j.jclepro.2017.03.218 2-s2.0-85018586730 2-s2.0-85018586730.pdf 4390073683610512 |
url |
http://dx.doi.org/10.1016/j.jclepro.2017.03.218 http://hdl.handle.net/11449/178838 |
identifier_str_mv |
Journal of Cleaner Production, v. 154, p. 233-241. 0959-6526 10.1016/j.jclepro.2017.03.218 2-s2.0-85018586730 2-s2.0-85018586730.pdf 4390073683610512 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Cleaner Production 1,467 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
233-241 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808129468054634496 |