Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases

Detalhes bibliográficos
Autor(a) principal: Gomes, Mônica Fernandes [UNESP]
Data de Publicação: 2018
Outros Autores: Sichi, Luigi Giovanni Bernardo [UNESP], Giannasi, Lilian Chrystiane [UNESP], Amorim, José Benedito Oliveira [UNESP], Rocha, João Carlos Da [UNESP], Koga-Ito, Cristiane Yumi [UNESP], Salgado, Miguel Angel Castillo [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1155/2018/2409212
http://hdl.handle.net/11449/179898
Resumo: Ectodermal dysplasia (ED) is a rare hereditary disorder affecting the development of ectoderm-derived organs and tissues. The aim of this study was to describe phenotypic features and the therapeutic approach in dentistry among three patients with ED, correlating their data with the literature. Additionally, to investigate the salivary gland disorders and their impacts on oral microbiota, we performed salivary tests, including salivary flow rate, salivary buffering capacity, and concentration levels of mutans streptococci, lactobacilli, and yeasts. All patients presented oligodontia, resulting in a significant masticatory dysfunction and aesthetic impairment. The counts of mutans streptococci n=3 and yeasts n=2 were high; on the other hand, the count of lactobacilli n=3 was low. Therefore, salivary and microbiological tests showed that the patients with ED, particularly the hypohidrotic type, presented a high risk of enamel caries and susceptibility to oral infections, which may be likely triggered by reduction of salivary flow and/or possible immunological disorders.
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spelling Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three CasesEctodermal dysplasia (ED) is a rare hereditary disorder affecting the development of ectoderm-derived organs and tissues. The aim of this study was to describe phenotypic features and the therapeutic approach in dentistry among three patients with ED, correlating their data with the literature. Additionally, to investigate the salivary gland disorders and their impacts on oral microbiota, we performed salivary tests, including salivary flow rate, salivary buffering capacity, and concentration levels of mutans streptococci, lactobacilli, and yeasts. All patients presented oligodontia, resulting in a significant masticatory dysfunction and aesthetic impairment. The counts of mutans streptococci n=3 and yeasts n=2 were high; on the other hand, the count of lactobacilli n=3 was low. Therefore, salivary and microbiological tests showed that the patients with ED, particularly the hypohidrotic type, presented a high risk of enamel caries and susceptibility to oral infections, which may be likely triggered by reduction of salivary flow and/or possible immunological disorders.Center of Biosciences Applied to Patients with Special Health Care Needs (CEPAPE) Institute of Science and Technology São Jose Dos Campos Campus São Paulo State University-UNESPDental School Metropolitan University of Santos (UNIMES)Sleep Disorders Laboratory Universitary Center of Anápolis (UniEvangelica)Center of Biosciences Applied to Patients with Special Health Care Needs (CEPAPE) Institute of Science and Technology São Jose Dos Campos Campus São Paulo State University-UNESPUniversidade Estadual Paulista (Unesp)Metropolitan University of Santos (UNIMES)Universitary Center of Anápolis (UniEvangelica)Gomes, Mônica Fernandes [UNESP]Sichi, Luigi Giovanni Bernardo [UNESP]Giannasi, Lilian Chrystiane [UNESP]Amorim, José Benedito Oliveira [UNESP]Rocha, João Carlos Da [UNESP]Koga-Ito, Cristiane Yumi [UNESP]Salgado, Miguel Angel Castillo [UNESP]2018-12-11T17:37:12Z2018-12-11T17:37:12Z2018-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1155/2018/2409212Case Reports in Dentistry, v. 2018.2090-64552090-6447http://hdl.handle.net/11449/17989810.1155/2018/24092122-s2.0-850476239262-s2.0-85047623926.pdf8235700830441386127422545567840065435631614034210000-0002-2416-2173Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCase Reports in Dentistry0,2290,229info:eu-repo/semantics/openAccess2023-12-14T06:17:01Zoai:repositorio.unesp.br:11449/179898Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:16:34.473953Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases
title Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases
spellingShingle Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases
Gomes, Mônica Fernandes [UNESP]
title_short Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases
title_full Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases
title_fullStr Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases
title_full_unstemmed Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases
title_sort Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases
author Gomes, Mônica Fernandes [UNESP]
author_facet Gomes, Mônica Fernandes [UNESP]
Sichi, Luigi Giovanni Bernardo [UNESP]
Giannasi, Lilian Chrystiane [UNESP]
Amorim, José Benedito Oliveira [UNESP]
Rocha, João Carlos Da [UNESP]
Koga-Ito, Cristiane Yumi [UNESP]
Salgado, Miguel Angel Castillo [UNESP]
author_role author
author2 Sichi, Luigi Giovanni Bernardo [UNESP]
Giannasi, Lilian Chrystiane [UNESP]
Amorim, José Benedito Oliveira [UNESP]
Rocha, João Carlos Da [UNESP]
Koga-Ito, Cristiane Yumi [UNESP]
Salgado, Miguel Angel Castillo [UNESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Metropolitan University of Santos (UNIMES)
Universitary Center of Anápolis (UniEvangelica)
dc.contributor.author.fl_str_mv Gomes, Mônica Fernandes [UNESP]
Sichi, Luigi Giovanni Bernardo [UNESP]
Giannasi, Lilian Chrystiane [UNESP]
Amorim, José Benedito Oliveira [UNESP]
Rocha, João Carlos Da [UNESP]
Koga-Ito, Cristiane Yumi [UNESP]
Salgado, Miguel Angel Castillo [UNESP]
description Ectodermal dysplasia (ED) is a rare hereditary disorder affecting the development of ectoderm-derived organs and tissues. The aim of this study was to describe phenotypic features and the therapeutic approach in dentistry among three patients with ED, correlating their data with the literature. Additionally, to investigate the salivary gland disorders and their impacts on oral microbiota, we performed salivary tests, including salivary flow rate, salivary buffering capacity, and concentration levels of mutans streptococci, lactobacilli, and yeasts. All patients presented oligodontia, resulting in a significant masticatory dysfunction and aesthetic impairment. The counts of mutans streptococci n=3 and yeasts n=2 were high; on the other hand, the count of lactobacilli n=3 was low. Therefore, salivary and microbiological tests showed that the patients with ED, particularly the hypohidrotic type, presented a high risk of enamel caries and susceptibility to oral infections, which may be likely triggered by reduction of salivary flow and/or possible immunological disorders.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-11T17:37:12Z
2018-12-11T17:37:12Z
2018-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1155/2018/2409212
Case Reports in Dentistry, v. 2018.
2090-6455
2090-6447
http://hdl.handle.net/11449/179898
10.1155/2018/2409212
2-s2.0-85047623926
2-s2.0-85047623926.pdf
8235700830441386
1274225455678400
6543563161403421
0000-0002-2416-2173
url http://dx.doi.org/10.1155/2018/2409212
http://hdl.handle.net/11449/179898
identifier_str_mv Case Reports in Dentistry, v. 2018.
2090-6455
2090-6447
10.1155/2018/2409212
2-s2.0-85047623926
2-s2.0-85047623926.pdf
8235700830441386
1274225455678400
6543563161403421
0000-0002-2416-2173
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Case Reports in Dentistry
0,229
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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