Taurine supplementation increases irisin levels after high intensity physical training in obese women
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.cyto.2019.154741 http://hdl.handle.net/11449/196197 |
Resumo: | Background: Irisin is a myokine/adipokine that under stimulus of physical exercise is able to improve thermogenic capacity in adipose tissue. Likewise, taurine supplementation has demonstrated similar effects on energy metabolism. Therefore, we hypothesized that taurine supplementation combined with physical training may induce an increase in irisin concentrations, optimizing energy metabolism in obese individuals. Objective: To evaluate if taurine supplementation associated with a high intensity physical training program increases irisin levels in obese women. Methods: double-blind study with 22 obese women (BMI 32.4 2.0 kg/m(2), 36.6 +/- 6.4 years and sedentary) who were randomly divided into two groups, control group (GC, n = 14), exercised and supplemented with placebo (3 g of starch), and taurine group (GTAU, n = 8), exercised and supplemented with taurine (3 g). The subjects performed high intensity physical training, Deep Water Running (DWR), for 8 weeks, 3 times/week, for 50 min per training session, at 70-85% maximum heart rate. Resting metabolic rate (RMR) was evaluated by indirect calorimetry, body composition by deuterium oxide, plasma taurine by HPLC, plasma irisin by Multiplex Kit, and food consumption by food records. The results were analyzed by an ANOVA two way repeated measures mixed model, with the Sidak post hoc (p < 0.05). Results: No changes were observed in body composition. DWR increased RMR independent of supplementation (p < 0.001) and irisin levels (pg/mL) showed a significant difference only in the GTAU in 1 h after exercise (p < 0.001). Conclusion: DWR associated with taurine supplementation resulted in increased plasma irisin concentrations after physical training in obese adult women. |
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Taurine supplementation increases irisin levels after high intensity physical training in obese womenObesityIrisinTaurineDeep water runningEnergy expenditureBackground: Irisin is a myokine/adipokine that under stimulus of physical exercise is able to improve thermogenic capacity in adipose tissue. Likewise, taurine supplementation has demonstrated similar effects on energy metabolism. Therefore, we hypothesized that taurine supplementation combined with physical training may induce an increase in irisin concentrations, optimizing energy metabolism in obese individuals. Objective: To evaluate if taurine supplementation associated with a high intensity physical training program increases irisin levels in obese women. Methods: double-blind study with 22 obese women (BMI 32.4 2.0 kg/m(2), 36.6 +/- 6.4 years and sedentary) who were randomly divided into two groups, control group (GC, n = 14), exercised and supplemented with placebo (3 g of starch), and taurine group (GTAU, n = 8), exercised and supplemented with taurine (3 g). The subjects performed high intensity physical training, Deep Water Running (DWR), for 8 weeks, 3 times/week, for 50 min per training session, at 70-85% maximum heart rate. Resting metabolic rate (RMR) was evaluated by indirect calorimetry, body composition by deuterium oxide, plasma taurine by HPLC, plasma irisin by Multiplex Kit, and food consumption by food records. The results were analyzed by an ANOVA two way repeated measures mixed model, with the Sidak post hoc (p < 0.05). Results: No changes were observed in body composition. DWR increased RMR independent of supplementation (p < 0.001) and irisin levels (pg/mL) showed a significant difference only in the GTAU in 1 h after exercise (p < 0.001). Conclusion: DWR associated with taurine supplementation resulted in increased plasma irisin concentrations after physical training in obese adult women.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)State Univ Sao Paulo, Sch Pharmaceut Sci Araraquara, Dept Food & Nutr, Rod Araraquara Jau Km 1, Araraquara, SP, BrazilUniv Sao Paulo, Ribeirao Preto Med Sch, Ave Bandeirantes 3900, Ribeirao Preto, SP, BrazilUniv Sao Paulo, Sch Phys Educ & Sport Ribeirao Preto, Ave Bandeirantes 3900, BR-14049900 Ribeirao Preto, SP, BrazilUniv Sao Paulo, Ribeirao Preto Med Sch, Dept Pharmacol, Ave Bandeirantes 3900, Ribeirao Preto, SP, BrazilState Univ Sao Paulo, Sch Pharmaceut Sci Araraquara, Dept Food & Nutr, Rod Araraquara Jau Km 1, Araraquara, SP, BrazilCAPES: 001FAPESP: 2017/10080-2FAPESP: 2018/19107-3FAPESP: 2017/08036-5Elsevier B.V.Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Batitucci, Gabriela [UNESP]Cunha Brandao, Camila FernandaDe Carvalho, Flavia GioloMarchini, Julio SergioPfrimer, KarmaFerrioli, EduardoCunha, Fernando QueirozPapoti, MarceloBarros Morhy Terrazas, Sara Ivone [UNESP]Junqueira-Franco, Marcia Varella MorandiRamos da Silva, Adelino SanchezFreitasa, Ellen Cristini de [UNESP]2020-12-10T19:36:43Z2020-12-10T19:36:43Z2019-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article6http://dx.doi.org/10.1016/j.cyto.2019.154741Cytokine. London: Academic Press Ltd- Elsevier Science Ltd, v. 123, 6 p., 2019.1043-4666http://hdl.handle.net/11449/19619710.1016/j.cyto.2019.154741WOS:000487576400010Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCytokineinfo:eu-repo/semantics/openAccess2024-06-21T12:46:49Zoai:repositorio.unesp.br:11449/196197Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:38:25.672084Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Taurine supplementation increases irisin levels after high intensity physical training in obese women |
title |
Taurine supplementation increases irisin levels after high intensity physical training in obese women |
spellingShingle |
Taurine supplementation increases irisin levels after high intensity physical training in obese women Batitucci, Gabriela [UNESP] Obesity Irisin Taurine Deep water running Energy expenditure |
title_short |
Taurine supplementation increases irisin levels after high intensity physical training in obese women |
title_full |
Taurine supplementation increases irisin levels after high intensity physical training in obese women |
title_fullStr |
Taurine supplementation increases irisin levels after high intensity physical training in obese women |
title_full_unstemmed |
Taurine supplementation increases irisin levels after high intensity physical training in obese women |
title_sort |
Taurine supplementation increases irisin levels after high intensity physical training in obese women |
author |
Batitucci, Gabriela [UNESP] |
author_facet |
Batitucci, Gabriela [UNESP] Cunha Brandao, Camila Fernanda De Carvalho, Flavia Giolo Marchini, Julio Sergio Pfrimer, Karma Ferrioli, Eduardo Cunha, Fernando Queiroz Papoti, Marcelo Barros Morhy Terrazas, Sara Ivone [UNESP] Junqueira-Franco, Marcia Varella Morandi Ramos da Silva, Adelino Sanchez Freitasa, Ellen Cristini de [UNESP] |
author_role |
author |
author2 |
Cunha Brandao, Camila Fernanda De Carvalho, Flavia Giolo Marchini, Julio Sergio Pfrimer, Karma Ferrioli, Eduardo Cunha, Fernando Queiroz Papoti, Marcelo Barros Morhy Terrazas, Sara Ivone [UNESP] Junqueira-Franco, Marcia Varella Morandi Ramos da Silva, Adelino Sanchez Freitasa, Ellen Cristini de [UNESP] |
author2_role |
author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Batitucci, Gabriela [UNESP] Cunha Brandao, Camila Fernanda De Carvalho, Flavia Giolo Marchini, Julio Sergio Pfrimer, Karma Ferrioli, Eduardo Cunha, Fernando Queiroz Papoti, Marcelo Barros Morhy Terrazas, Sara Ivone [UNESP] Junqueira-Franco, Marcia Varella Morandi Ramos da Silva, Adelino Sanchez Freitasa, Ellen Cristini de [UNESP] |
dc.subject.por.fl_str_mv |
Obesity Irisin Taurine Deep water running Energy expenditure |
topic |
Obesity Irisin Taurine Deep water running Energy expenditure |
description |
Background: Irisin is a myokine/adipokine that under stimulus of physical exercise is able to improve thermogenic capacity in adipose tissue. Likewise, taurine supplementation has demonstrated similar effects on energy metabolism. Therefore, we hypothesized that taurine supplementation combined with physical training may induce an increase in irisin concentrations, optimizing energy metabolism in obese individuals. Objective: To evaluate if taurine supplementation associated with a high intensity physical training program increases irisin levels in obese women. Methods: double-blind study with 22 obese women (BMI 32.4 2.0 kg/m(2), 36.6 +/- 6.4 years and sedentary) who were randomly divided into two groups, control group (GC, n = 14), exercised and supplemented with placebo (3 g of starch), and taurine group (GTAU, n = 8), exercised and supplemented with taurine (3 g). The subjects performed high intensity physical training, Deep Water Running (DWR), for 8 weeks, 3 times/week, for 50 min per training session, at 70-85% maximum heart rate. Resting metabolic rate (RMR) was evaluated by indirect calorimetry, body composition by deuterium oxide, plasma taurine by HPLC, plasma irisin by Multiplex Kit, and food consumption by food records. The results were analyzed by an ANOVA two way repeated measures mixed model, with the Sidak post hoc (p < 0.05). Results: No changes were observed in body composition. DWR increased RMR independent of supplementation (p < 0.001) and irisin levels (pg/mL) showed a significant difference only in the GTAU in 1 h after exercise (p < 0.001). Conclusion: DWR associated with taurine supplementation resulted in increased plasma irisin concentrations after physical training in obese adult women. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-11-01 2020-12-10T19:36:43Z 2020-12-10T19:36:43Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.cyto.2019.154741 Cytokine. London: Academic Press Ltd- Elsevier Science Ltd, v. 123, 6 p., 2019. 1043-4666 http://hdl.handle.net/11449/196197 10.1016/j.cyto.2019.154741 WOS:000487576400010 |
url |
http://dx.doi.org/10.1016/j.cyto.2019.154741 http://hdl.handle.net/11449/196197 |
identifier_str_mv |
Cytokine. London: Academic Press Ltd- Elsevier Science Ltd, v. 123, 6 p., 2019. 1043-4666 10.1016/j.cyto.2019.154741 WOS:000487576400010 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Cytokine |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
6 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128682128048128 |