Taurine supplementation increases irisin levels after high intensity physical training in obese women

Detalhes bibliográficos
Autor(a) principal: Batitucci, Gabriela [UNESP]
Data de Publicação: 2019
Outros Autores: Cunha Brandao, Camila Fernanda, De Carvalho, Flavia Giolo, Marchini, Julio Sergio, Pfrimer, Karma, Ferrioli, Eduardo, Cunha, Fernando Queiroz, Papoti, Marcelo, Barros Morhy Terrazas, Sara Ivone [UNESP], Junqueira-Franco, Marcia Varella Morandi, Ramos da Silva, Adelino Sanchez, Freitasa, Ellen Cristini de [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.cyto.2019.154741
http://hdl.handle.net/11449/196197
Resumo: Background: Irisin is a myokine/adipokine that under stimulus of physical exercise is able to improve thermogenic capacity in adipose tissue. Likewise, taurine supplementation has demonstrated similar effects on energy metabolism. Therefore, we hypothesized that taurine supplementation combined with physical training may induce an increase in irisin concentrations, optimizing energy metabolism in obese individuals. Objective: To evaluate if taurine supplementation associated with a high intensity physical training program increases irisin levels in obese women. Methods: double-blind study with 22 obese women (BMI 32.4 2.0 kg/m(2), 36.6 +/- 6.4 years and sedentary) who were randomly divided into two groups, control group (GC, n = 14), exercised and supplemented with placebo (3 g of starch), and taurine group (GTAU, n = 8), exercised and supplemented with taurine (3 g). The subjects performed high intensity physical training, Deep Water Running (DWR), for 8 weeks, 3 times/week, for 50 min per training session, at 70-85% maximum heart rate. Resting metabolic rate (RMR) was evaluated by indirect calorimetry, body composition by deuterium oxide, plasma taurine by HPLC, plasma irisin by Multiplex Kit, and food consumption by food records. The results were analyzed by an ANOVA two way repeated measures mixed model, with the Sidak post hoc (p < 0.05). Results: No changes were observed in body composition. DWR increased RMR independent of supplementation (p < 0.001) and irisin levels (pg/mL) showed a significant difference only in the GTAU in 1 h after exercise (p < 0.001). Conclusion: DWR associated with taurine supplementation resulted in increased plasma irisin concentrations after physical training in obese adult women.
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spelling Taurine supplementation increases irisin levels after high intensity physical training in obese womenObesityIrisinTaurineDeep water runningEnergy expenditureBackground: Irisin is a myokine/adipokine that under stimulus of physical exercise is able to improve thermogenic capacity in adipose tissue. Likewise, taurine supplementation has demonstrated similar effects on energy metabolism. Therefore, we hypothesized that taurine supplementation combined with physical training may induce an increase in irisin concentrations, optimizing energy metabolism in obese individuals. Objective: To evaluate if taurine supplementation associated with a high intensity physical training program increases irisin levels in obese women. Methods: double-blind study with 22 obese women (BMI 32.4 2.0 kg/m(2), 36.6 +/- 6.4 years and sedentary) who were randomly divided into two groups, control group (GC, n = 14), exercised and supplemented with placebo (3 g of starch), and taurine group (GTAU, n = 8), exercised and supplemented with taurine (3 g). The subjects performed high intensity physical training, Deep Water Running (DWR), for 8 weeks, 3 times/week, for 50 min per training session, at 70-85% maximum heart rate. Resting metabolic rate (RMR) was evaluated by indirect calorimetry, body composition by deuterium oxide, plasma taurine by HPLC, plasma irisin by Multiplex Kit, and food consumption by food records. The results were analyzed by an ANOVA two way repeated measures mixed model, with the Sidak post hoc (p < 0.05). Results: No changes were observed in body composition. DWR increased RMR independent of supplementation (p < 0.001) and irisin levels (pg/mL) showed a significant difference only in the GTAU in 1 h after exercise (p < 0.001). Conclusion: DWR associated with taurine supplementation resulted in increased plasma irisin concentrations after physical training in obese adult women.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)State Univ Sao Paulo, Sch Pharmaceut Sci Araraquara, Dept Food & Nutr, Rod Araraquara Jau Km 1, Araraquara, SP, BrazilUniv Sao Paulo, Ribeirao Preto Med Sch, Ave Bandeirantes 3900, Ribeirao Preto, SP, BrazilUniv Sao Paulo, Sch Phys Educ & Sport Ribeirao Preto, Ave Bandeirantes 3900, BR-14049900 Ribeirao Preto, SP, BrazilUniv Sao Paulo, Ribeirao Preto Med Sch, Dept Pharmacol, Ave Bandeirantes 3900, Ribeirao Preto, SP, BrazilState Univ Sao Paulo, Sch Pharmaceut Sci Araraquara, Dept Food & Nutr, Rod Araraquara Jau Km 1, Araraquara, SP, BrazilCAPES: 001FAPESP: 2017/10080-2FAPESP: 2018/19107-3FAPESP: 2017/08036-5Elsevier B.V.Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Batitucci, Gabriela [UNESP]Cunha Brandao, Camila FernandaDe Carvalho, Flavia GioloMarchini, Julio SergioPfrimer, KarmaFerrioli, EduardoCunha, Fernando QueirozPapoti, MarceloBarros Morhy Terrazas, Sara Ivone [UNESP]Junqueira-Franco, Marcia Varella MorandiRamos da Silva, Adelino SanchezFreitasa, Ellen Cristini de [UNESP]2020-12-10T19:36:43Z2020-12-10T19:36:43Z2019-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article6http://dx.doi.org/10.1016/j.cyto.2019.154741Cytokine. London: Academic Press Ltd- Elsevier Science Ltd, v. 123, 6 p., 2019.1043-4666http://hdl.handle.net/11449/19619710.1016/j.cyto.2019.154741WOS:000487576400010Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCytokineinfo:eu-repo/semantics/openAccess2024-06-21T12:46:49Zoai:repositorio.unesp.br:11449/196197Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:38:25.672084Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Taurine supplementation increases irisin levels after high intensity physical training in obese women
title Taurine supplementation increases irisin levels after high intensity physical training in obese women
spellingShingle Taurine supplementation increases irisin levels after high intensity physical training in obese women
Batitucci, Gabriela [UNESP]
Obesity
Irisin
Taurine
Deep water running
Energy expenditure
title_short Taurine supplementation increases irisin levels after high intensity physical training in obese women
title_full Taurine supplementation increases irisin levels after high intensity physical training in obese women
title_fullStr Taurine supplementation increases irisin levels after high intensity physical training in obese women
title_full_unstemmed Taurine supplementation increases irisin levels after high intensity physical training in obese women
title_sort Taurine supplementation increases irisin levels after high intensity physical training in obese women
author Batitucci, Gabriela [UNESP]
author_facet Batitucci, Gabriela [UNESP]
Cunha Brandao, Camila Fernanda
De Carvalho, Flavia Giolo
Marchini, Julio Sergio
Pfrimer, Karma
Ferrioli, Eduardo
Cunha, Fernando Queiroz
Papoti, Marcelo
Barros Morhy Terrazas, Sara Ivone [UNESP]
Junqueira-Franco, Marcia Varella Morandi
Ramos da Silva, Adelino Sanchez
Freitasa, Ellen Cristini de [UNESP]
author_role author
author2 Cunha Brandao, Camila Fernanda
De Carvalho, Flavia Giolo
Marchini, Julio Sergio
Pfrimer, Karma
Ferrioli, Eduardo
Cunha, Fernando Queiroz
Papoti, Marcelo
Barros Morhy Terrazas, Sara Ivone [UNESP]
Junqueira-Franco, Marcia Varella Morandi
Ramos da Silva, Adelino Sanchez
Freitasa, Ellen Cristini de [UNESP]
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Batitucci, Gabriela [UNESP]
Cunha Brandao, Camila Fernanda
De Carvalho, Flavia Giolo
Marchini, Julio Sergio
Pfrimer, Karma
Ferrioli, Eduardo
Cunha, Fernando Queiroz
Papoti, Marcelo
Barros Morhy Terrazas, Sara Ivone [UNESP]
Junqueira-Franco, Marcia Varella Morandi
Ramos da Silva, Adelino Sanchez
Freitasa, Ellen Cristini de [UNESP]
dc.subject.por.fl_str_mv Obesity
Irisin
Taurine
Deep water running
Energy expenditure
topic Obesity
Irisin
Taurine
Deep water running
Energy expenditure
description Background: Irisin is a myokine/adipokine that under stimulus of physical exercise is able to improve thermogenic capacity in adipose tissue. Likewise, taurine supplementation has demonstrated similar effects on energy metabolism. Therefore, we hypothesized that taurine supplementation combined with physical training may induce an increase in irisin concentrations, optimizing energy metabolism in obese individuals. Objective: To evaluate if taurine supplementation associated with a high intensity physical training program increases irisin levels in obese women. Methods: double-blind study with 22 obese women (BMI 32.4 2.0 kg/m(2), 36.6 +/- 6.4 years and sedentary) who were randomly divided into two groups, control group (GC, n = 14), exercised and supplemented with placebo (3 g of starch), and taurine group (GTAU, n = 8), exercised and supplemented with taurine (3 g). The subjects performed high intensity physical training, Deep Water Running (DWR), for 8 weeks, 3 times/week, for 50 min per training session, at 70-85% maximum heart rate. Resting metabolic rate (RMR) was evaluated by indirect calorimetry, body composition by deuterium oxide, plasma taurine by HPLC, plasma irisin by Multiplex Kit, and food consumption by food records. The results were analyzed by an ANOVA two way repeated measures mixed model, with the Sidak post hoc (p < 0.05). Results: No changes were observed in body composition. DWR increased RMR independent of supplementation (p < 0.001) and irisin levels (pg/mL) showed a significant difference only in the GTAU in 1 h after exercise (p < 0.001). Conclusion: DWR associated with taurine supplementation resulted in increased plasma irisin concentrations after physical training in obese adult women.
publishDate 2019
dc.date.none.fl_str_mv 2019-11-01
2020-12-10T19:36:43Z
2020-12-10T19:36:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.cyto.2019.154741
Cytokine. London: Academic Press Ltd- Elsevier Science Ltd, v. 123, 6 p., 2019.
1043-4666
http://hdl.handle.net/11449/196197
10.1016/j.cyto.2019.154741
WOS:000487576400010
url http://dx.doi.org/10.1016/j.cyto.2019.154741
http://hdl.handle.net/11449/196197
identifier_str_mv Cytokine. London: Academic Press Ltd- Elsevier Science Ltd, v. 123, 6 p., 2019.
1043-4666
10.1016/j.cyto.2019.154741
WOS:000487576400010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Cytokine
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 6
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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