The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material : an in vitro study
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/200546 |
Resumo: | Candida albicans is the main causative pathogen of denture stomatitis, which affects many complete denture patients. Objective: To evaluate the effect of different concentrations of nanodiamonds (NDs) added to polymethyl methacrylate (PMMA) denture base material on Candida albicans adhesion as well as on surface roughness and contact angle. Methodology: Acrylic resin specimens sized 10×10×3 mm3 were prepared and divided into four groups (n=30) according to ND concentration (0%, 0.5%, 1%, 1.5% by wt). Surface roughness was measured with a profilometer, and the contact angle with a goniometer. The effect of NDs on Candida albicans adhesion was evaluated using two methods: 1) slide count and 2) direct culture test. Analysis of variance (ANOVA) and Tukey's post hoc test were used in the statistical analyses. Results: Addition of NDs decreased the Candida albicans count significantly more than in the control group (p<0.05), with a lowest of 1% NDs. Addition of NDs also significantly decreased the surface roughness (p<0.05), but the contact angle remained the same. Incorporation of NDs into the PMMA denture base material effectively reduced Candida albicans adhesion and decreased surface roughness. Conclusion: PMMA/NDs composites could be valuable in the prevention of denture stomatitis, which is considered one of the most common clinical problems among removable denture wearers. |
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Journal of applied oral science (Online) |
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The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material : an in vitro studyCandida albicansDenture stomatitisPMMANanodiamondsDenture baseCandida albicans is the main causative pathogen of denture stomatitis, which affects many complete denture patients. Objective: To evaluate the effect of different concentrations of nanodiamonds (NDs) added to polymethyl methacrylate (PMMA) denture base material on Candida albicans adhesion as well as on surface roughness and contact angle. Methodology: Acrylic resin specimens sized 10×10×3 mm3 were prepared and divided into four groups (n=30) according to ND concentration (0%, 0.5%, 1%, 1.5% by wt). Surface roughness was measured with a profilometer, and the contact angle with a goniometer. The effect of NDs on Candida albicans adhesion was evaluated using two methods: 1) slide count and 2) direct culture test. Analysis of variance (ANOVA) and Tukey's post hoc test were used in the statistical analyses. Results: Addition of NDs decreased the Candida albicans count significantly more than in the control group (p<0.05), with a lowest of 1% NDs. Addition of NDs also significantly decreased the surface roughness (p<0.05), but the contact angle remained the same. Incorporation of NDs into the PMMA denture base material effectively reduced Candida albicans adhesion and decreased surface roughness. Conclusion: PMMA/NDs composites could be valuable in the prevention of denture stomatitis, which is considered one of the most common clinical problems among removable denture wearers.Universidade de São Paulo. Faculdade de Odontologia de Bauru2022-07-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/20054610.1590/1678-7757-2018-0779Journal of Applied Oral Science; Vol. 27 (2019); e20180779Journal of Applied Oral Science; Vol. 27 (2019); e20180779Journal of Applied Oral Science; v. 27 (2019); e201807791678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/200546/184755Copyright (c) 2022 Journal of Applied Oral Sciencehttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFouda, Shaimaa M. Gad, Mohammed M. Ellakany, Passent Al-Thobity, Ahmad M. Al-Harbi, Fahad A. Virtanen, Jorma I. Raustia, Aune 2022-07-29T19:16:11Zoai:revistas.usp.br:article/200546Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2022-07-29T19:16:11Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material : an in vitro study |
title |
The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material : an in vitro study |
spellingShingle |
The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material : an in vitro study Fouda, Shaimaa M. Candida albicans Denture stomatitis PMMA Nanodiamonds Denture base |
title_short |
The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material : an in vitro study |
title_full |
The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material : an in vitro study |
title_fullStr |
The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material : an in vitro study |
title_full_unstemmed |
The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material : an in vitro study |
title_sort |
The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material : an in vitro study |
author |
Fouda, Shaimaa M. |
author_facet |
Fouda, Shaimaa M. Gad, Mohammed M. Ellakany, Passent Al-Thobity, Ahmad M. Al-Harbi, Fahad A. Virtanen, Jorma I. Raustia, Aune |
author_role |
author |
author2 |
Gad, Mohammed M. Ellakany, Passent Al-Thobity, Ahmad M. Al-Harbi, Fahad A. Virtanen, Jorma I. Raustia, Aune |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Fouda, Shaimaa M. Gad, Mohammed M. Ellakany, Passent Al-Thobity, Ahmad M. Al-Harbi, Fahad A. Virtanen, Jorma I. Raustia, Aune |
dc.subject.por.fl_str_mv |
Candida albicans Denture stomatitis PMMA Nanodiamonds Denture base |
topic |
Candida albicans Denture stomatitis PMMA Nanodiamonds Denture base |
description |
Candida albicans is the main causative pathogen of denture stomatitis, which affects many complete denture patients. Objective: To evaluate the effect of different concentrations of nanodiamonds (NDs) added to polymethyl methacrylate (PMMA) denture base material on Candida albicans adhesion as well as on surface roughness and contact angle. Methodology: Acrylic resin specimens sized 10×10×3 mm3 were prepared and divided into four groups (n=30) according to ND concentration (0%, 0.5%, 1%, 1.5% by wt). Surface roughness was measured with a profilometer, and the contact angle with a goniometer. The effect of NDs on Candida albicans adhesion was evaluated using two methods: 1) slide count and 2) direct culture test. Analysis of variance (ANOVA) and Tukey's post hoc test were used in the statistical analyses. Results: Addition of NDs decreased the Candida albicans count significantly more than in the control group (p<0.05), with a lowest of 1% NDs. Addition of NDs also significantly decreased the surface roughness (p<0.05), but the contact angle remained the same. Incorporation of NDs into the PMMA denture base material effectively reduced Candida albicans adhesion and decreased surface roughness. Conclusion: PMMA/NDs composites could be valuable in the prevention of denture stomatitis, which is considered one of the most common clinical problems among removable denture wearers. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-07-29 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/200546 10.1590/1678-7757-2018-0779 |
url |
https://www.revistas.usp.br/jaos/article/view/200546 |
identifier_str_mv |
10.1590/1678-7757-2018-0779 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/200546/184755 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Journal of Applied Oral Science http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Journal of Applied Oral Science http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 27 (2019); e20180779 Journal of Applied Oral Science; Vol. 27 (2019); e20180779 Journal of Applied Oral Science; v. 27 (2019); e20180779 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221682669977600 |