Pulp tissue from primary teeth: new source of stem cells
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/3893 |
Resumo: | SHED (stem cells from human exfoliated deciduous teeth) represent a population of postnatal stem cells capable of extensive proliferation and multipotential differentiation. Primary teeth may be an ideal source of postnatal stem cells to regenerate tooth structures and bone, and possibly to treat neural tissue injury or degenerative diseases. SHED are highly proliferative cells derived from an accessible tissue source, and therefore hold potential for providing enough cells for clinical applications. In this review, we describe the current knowledge about dental pulp stem cells and discuss tissue engineering approaches that use SHED to replace irreversibly inflamed or necrotic pulps with a healthy and functionally competent tissue that is capable of forming new dentin. |
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Pulp tissue from primary teeth: new source of stem cells Tissue regenerationDental pulpTissue engineeringendodontics SHED (stem cells from human exfoliated deciduous teeth) represent a population of postnatal stem cells capable of extensive proliferation and multipotential differentiation. Primary teeth may be an ideal source of postnatal stem cells to regenerate tooth structures and bone, and possibly to treat neural tissue injury or degenerative diseases. SHED are highly proliferative cells derived from an accessible tissue source, and therefore hold potential for providing enough cells for clinical applications. In this review, we describe the current knowledge about dental pulp stem cells and discuss tissue engineering approaches that use SHED to replace irreversibly inflamed or necrotic pulps with a healthy and functionally competent tissue that is capable of forming new dentin. Universidade de São Paulo. Faculdade de Odontologia de Bauru2011-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/389310.1590/S1678-77572011000300002Journal of Applied Oral Science; Vol. 19 No. 3 (2011); 189-194 Journal of Applied Oral Science; Vol. 19 Núm. 3 (2011); 189-194 Journal of Applied Oral Science; v. 19 n. 3 (2011); 189-194 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3893/4583Copyright (c) 2011 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessTelles, Paloma DiasMachado, Maria Aparecida de Andrade MoreiraSakai, Vivien ThiemyNör, Jacques Eduardo2012-04-27T12:13:20Zoai:revistas.usp.br:article/3893Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T12:13:20Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Pulp tissue from primary teeth: new source of stem cells |
title |
Pulp tissue from primary teeth: new source of stem cells |
spellingShingle |
Pulp tissue from primary teeth: new source of stem cells Telles, Paloma Dias Tissue regeneration Dental pulp Tissue engineering endodontics |
title_short |
Pulp tissue from primary teeth: new source of stem cells |
title_full |
Pulp tissue from primary teeth: new source of stem cells |
title_fullStr |
Pulp tissue from primary teeth: new source of stem cells |
title_full_unstemmed |
Pulp tissue from primary teeth: new source of stem cells |
title_sort |
Pulp tissue from primary teeth: new source of stem cells |
author |
Telles, Paloma Dias |
author_facet |
Telles, Paloma Dias Machado, Maria Aparecida de Andrade Moreira Sakai, Vivien Thiemy Nör, Jacques Eduardo |
author_role |
author |
author2 |
Machado, Maria Aparecida de Andrade Moreira Sakai, Vivien Thiemy Nör, Jacques Eduardo |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Telles, Paloma Dias Machado, Maria Aparecida de Andrade Moreira Sakai, Vivien Thiemy Nör, Jacques Eduardo |
dc.subject.por.fl_str_mv |
Tissue regeneration Dental pulp Tissue engineering endodontics |
topic |
Tissue regeneration Dental pulp Tissue engineering endodontics |
description |
SHED (stem cells from human exfoliated deciduous teeth) represent a population of postnatal stem cells capable of extensive proliferation and multipotential differentiation. Primary teeth may be an ideal source of postnatal stem cells to regenerate tooth structures and bone, and possibly to treat neural tissue injury or degenerative diseases. SHED are highly proliferative cells derived from an accessible tissue source, and therefore hold potential for providing enough cells for clinical applications. In this review, we describe the current knowledge about dental pulp stem cells and discuss tissue engineering approaches that use SHED to replace irreversibly inflamed or necrotic pulps with a healthy and functionally competent tissue that is capable of forming new dentin. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/3893 10.1590/S1678-77572011000300002 |
url |
https://www.revistas.usp.br/jaos/article/view/3893 |
identifier_str_mv |
10.1590/S1678-77572011000300002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/3893/4583 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2011 Journal of Applied Oral Science info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2011 Journal of Applied Oral Science |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 19 No. 3 (2011); 189-194 Journal of Applied Oral Science; Vol. 19 Núm. 3 (2011); 189-194 Journal of Applied Oral Science; v. 19 n. 3 (2011); 189-194 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221676221235200 |