Pulp tissue from primary teeth: new source of stem cells

Detalhes bibliográficos
Autor(a) principal: Telles, Paloma Dias
Data de Publicação: 2011
Outros Autores: Machado, Maria Aparecida de Andrade Moreira, Sakai, Vivien Thiemy, Nör, Jacques Eduardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/3893
Resumo: SHED (stem cells from human exfoliated deciduous teeth) represent a population of postnatal stem cells capable of extensive proliferation and multipotential differentiation. Primary teeth may be an ideal source of postnatal stem cells to regenerate tooth structures and bone, and possibly to treat neural tissue injury or degenerative diseases. SHED are highly proliferative cells derived from an accessible tissue source, and therefore hold potential for providing enough cells for clinical applications. In this review, we describe the current knowledge about dental pulp stem cells and discuss tissue engineering approaches that use SHED to replace irreversibly inflamed or necrotic pulps with a healthy and functionally competent tissue that is capable of forming new dentin.
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spelling Pulp tissue from primary teeth: new source of stem cells Tissue regenerationDental pulpTissue engineeringendodontics SHED (stem cells from human exfoliated deciduous teeth) represent a population of postnatal stem cells capable of extensive proliferation and multipotential differentiation. Primary teeth may be an ideal source of postnatal stem cells to regenerate tooth structures and bone, and possibly to treat neural tissue injury or degenerative diseases. SHED are highly proliferative cells derived from an accessible tissue source, and therefore hold potential for providing enough cells for clinical applications. In this review, we describe the current knowledge about dental pulp stem cells and discuss tissue engineering approaches that use SHED to replace irreversibly inflamed or necrotic pulps with a healthy and functionally competent tissue that is capable of forming new dentin. Universidade de São Paulo. Faculdade de Odontologia de Bauru2011-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/389310.1590/S1678-77572011000300002Journal of Applied Oral Science; Vol. 19 No. 3 (2011); 189-194 Journal of Applied Oral Science; Vol. 19 Núm. 3 (2011); 189-194 Journal of Applied Oral Science; v. 19 n. 3 (2011); 189-194 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3893/4583Copyright (c) 2011 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessTelles, Paloma DiasMachado, Maria Aparecida de Andrade MoreiraSakai, Vivien ThiemyNör, Jacques Eduardo2012-04-27T12:13:20Zoai:revistas.usp.br:article/3893Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T12:13:20Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Pulp tissue from primary teeth: new source of stem cells
title Pulp tissue from primary teeth: new source of stem cells
spellingShingle Pulp tissue from primary teeth: new source of stem cells
Telles, Paloma Dias
Tissue regeneration
Dental pulp
Tissue engineering
endodontics
title_short Pulp tissue from primary teeth: new source of stem cells
title_full Pulp tissue from primary teeth: new source of stem cells
title_fullStr Pulp tissue from primary teeth: new source of stem cells
title_full_unstemmed Pulp tissue from primary teeth: new source of stem cells
title_sort Pulp tissue from primary teeth: new source of stem cells
author Telles, Paloma Dias
author_facet Telles, Paloma Dias
Machado, Maria Aparecida de Andrade Moreira
Sakai, Vivien Thiemy
Nör, Jacques Eduardo
author_role author
author2 Machado, Maria Aparecida de Andrade Moreira
Sakai, Vivien Thiemy
Nör, Jacques Eduardo
author2_role author
author
author
dc.contributor.author.fl_str_mv Telles, Paloma Dias
Machado, Maria Aparecida de Andrade Moreira
Sakai, Vivien Thiemy
Nör, Jacques Eduardo
dc.subject.por.fl_str_mv Tissue regeneration
Dental pulp
Tissue engineering
endodontics
topic Tissue regeneration
Dental pulp
Tissue engineering
endodontics
description SHED (stem cells from human exfoliated deciduous teeth) represent a population of postnatal stem cells capable of extensive proliferation and multipotential differentiation. Primary teeth may be an ideal source of postnatal stem cells to regenerate tooth structures and bone, and possibly to treat neural tissue injury or degenerative diseases. SHED are highly proliferative cells derived from an accessible tissue source, and therefore hold potential for providing enough cells for clinical applications. In this review, we describe the current knowledge about dental pulp stem cells and discuss tissue engineering approaches that use SHED to replace irreversibly inflamed or necrotic pulps with a healthy and functionally competent tissue that is capable of forming new dentin.
publishDate 2011
dc.date.none.fl_str_mv 2011-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3893
10.1590/S1678-77572011000300002
url https://www.revistas.usp.br/jaos/article/view/3893
identifier_str_mv 10.1590/S1678-77572011000300002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3893/4583
dc.rights.driver.fl_str_mv Copyright (c) 2011 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2011 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 19 No. 3 (2011); 189-194
Journal of Applied Oral Science; Vol. 19 Núm. 3 (2011); 189-194
Journal of Applied Oral Science; v. 19 n. 3 (2011); 189-194
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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