Sugar-free chewing gum and dental caries: a systematic review

Detalhes bibliográficos
Autor(a) principal: Mickenautsch, Steffen
Data de Publicação: 2007
Outros Autores: Leal, Soraya Coelho, Yengopal, Veerasamy, Bezerra, Ana Cristina, Cruvinel, Vanessa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/3439
Resumo: OBJECTIVE: To appraise existing evidence for a therapeutic / anti-cariogenic effect of sugar-free chewing gum for patients. METHOD: 9 English and 2 Portuguese databases were searched using English and Portuguese keywords. Relevant articles in English, German, Portuguese and Spanish were included for review. Trials were excluded on lack of randomisation, control group, blinding and baseline data, drop out rate >;33%, no statistical adjustment of baseline differences and no assessment of clinically important outcomes. Reviews were excluded on lack of information, article selection criteria, search strategy followed, search keywords, searched databases or lack of study-by-study critique tables. In cases of multiple reports from the same study, the report covering the longest period was included. Two reviewers independently reviewed and assessed the quality of accepted articles. RESULTS: Thirty-nine articles were included for review. Thirty were excluded and 9 accepted. Of the 9 accepted, 2 trials of reasonable and good evidence value did not demonstrate any anti-cariogenic effect of sugar-free chewing gum. However, 7 articles, with 1 of strong, and 6 of good evidence value, demonstrated anti-cariogenic effects of chewing Sorbitol, Xylitol or Sorbitol/Xylitol gum. This effect can be ascribed to saliva stimulation through the chewing process, particularly when gum is used immediately after meals; the lack of sucrose and the inability of bacteria to metabolize polyols into acids. Conclusion: The evidence suggests that sugar-free chewing gum has a caries-reducing effect. Further well-designed randomised trials are needed to confirm these findings.
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spelling Sugar-free chewing gum and dental caries: a systematic review Sugar freeChewing gumCariesXylitolSorbitolRemineralisation OBJECTIVE: To appraise existing evidence for a therapeutic / anti-cariogenic effect of sugar-free chewing gum for patients. METHOD: 9 English and 2 Portuguese databases were searched using English and Portuguese keywords. Relevant articles in English, German, Portuguese and Spanish were included for review. Trials were excluded on lack of randomisation, control group, blinding and baseline data, drop out rate >;33%, no statistical adjustment of baseline differences and no assessment of clinically important outcomes. Reviews were excluded on lack of information, article selection criteria, search strategy followed, search keywords, searched databases or lack of study-by-study critique tables. In cases of multiple reports from the same study, the report covering the longest period was included. Two reviewers independently reviewed and assessed the quality of accepted articles. RESULTS: Thirty-nine articles were included for review. Thirty were excluded and 9 accepted. Of the 9 accepted, 2 trials of reasonable and good evidence value did not demonstrate any anti-cariogenic effect of sugar-free chewing gum. However, 7 articles, with 1 of strong, and 6 of good evidence value, demonstrated anti-cariogenic effects of chewing Sorbitol, Xylitol or Sorbitol/Xylitol gum. This effect can be ascribed to saliva stimulation through the chewing process, particularly when gum is used immediately after meals; the lack of sucrose and the inability of bacteria to metabolize polyols into acids. Conclusion: The evidence suggests that sugar-free chewing gum has a caries-reducing effect. Further well-designed randomised trials are needed to confirm these findings. Universidade de São Paulo. Faculdade de Odontologia de Bauru2007-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/343910.1590/S1678-77572007000200002Journal of Applied Oral Science; Vol. 15 No. 2 (2007); 83-88 Journal of Applied Oral Science; Vol. 15 Núm. 2 (2007); 83-88 Journal of Applied Oral Science; v. 15 n. 2 (2007); 83-88 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3439/4129Copyright (c) 2007 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessMickenautsch, SteffenLeal, Soraya CoelhoYengopal, VeerasamyBezerra, Ana CristinaCruvinel, Vanessa2012-04-27T11:56:33Zoai:revistas.usp.br:article/3439Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T11:56:33Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Sugar-free chewing gum and dental caries: a systematic review
title Sugar-free chewing gum and dental caries: a systematic review
spellingShingle Sugar-free chewing gum and dental caries: a systematic review
Mickenautsch, Steffen
Sugar free
Chewing gum
Caries
Xylitol
Sorbitol
Remineralisation
title_short Sugar-free chewing gum and dental caries: a systematic review
title_full Sugar-free chewing gum and dental caries: a systematic review
title_fullStr Sugar-free chewing gum and dental caries: a systematic review
title_full_unstemmed Sugar-free chewing gum and dental caries: a systematic review
title_sort Sugar-free chewing gum and dental caries: a systematic review
author Mickenautsch, Steffen
author_facet Mickenautsch, Steffen
Leal, Soraya Coelho
Yengopal, Veerasamy
Bezerra, Ana Cristina
Cruvinel, Vanessa
author_role author
author2 Leal, Soraya Coelho
Yengopal, Veerasamy
Bezerra, Ana Cristina
Cruvinel, Vanessa
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Mickenautsch, Steffen
Leal, Soraya Coelho
Yengopal, Veerasamy
Bezerra, Ana Cristina
Cruvinel, Vanessa
dc.subject.por.fl_str_mv Sugar free
Chewing gum
Caries
Xylitol
Sorbitol
Remineralisation
topic Sugar free
Chewing gum
Caries
Xylitol
Sorbitol
Remineralisation
description OBJECTIVE: To appraise existing evidence for a therapeutic / anti-cariogenic effect of sugar-free chewing gum for patients. METHOD: 9 English and 2 Portuguese databases were searched using English and Portuguese keywords. Relevant articles in English, German, Portuguese and Spanish were included for review. Trials were excluded on lack of randomisation, control group, blinding and baseline data, drop out rate >;33%, no statistical adjustment of baseline differences and no assessment of clinically important outcomes. Reviews were excluded on lack of information, article selection criteria, search strategy followed, search keywords, searched databases or lack of study-by-study critique tables. In cases of multiple reports from the same study, the report covering the longest period was included. Two reviewers independently reviewed and assessed the quality of accepted articles. RESULTS: Thirty-nine articles were included for review. Thirty were excluded and 9 accepted. Of the 9 accepted, 2 trials of reasonable and good evidence value did not demonstrate any anti-cariogenic effect of sugar-free chewing gum. However, 7 articles, with 1 of strong, and 6 of good evidence value, demonstrated anti-cariogenic effects of chewing Sorbitol, Xylitol or Sorbitol/Xylitol gum. This effect can be ascribed to saliva stimulation through the chewing process, particularly when gum is used immediately after meals; the lack of sucrose and the inability of bacteria to metabolize polyols into acids. Conclusion: The evidence suggests that sugar-free chewing gum has a caries-reducing effect. Further well-designed randomised trials are needed to confirm these findings.
publishDate 2007
dc.date.none.fl_str_mv 2007-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3439
10.1590/S1678-77572007000200002
url https://www.revistas.usp.br/jaos/article/view/3439
identifier_str_mv 10.1590/S1678-77572007000200002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3439/4129
dc.rights.driver.fl_str_mv Copyright (c) 2007 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2007 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 15 No. 2 (2007); 83-88
Journal of Applied Oral Science; Vol. 15 Núm. 2 (2007); 83-88
Journal of Applied Oral Science; v. 15 n. 2 (2007); 83-88
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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