Effects of hyaluronic acid on bleeding following third molar extraction
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/132892 |
Resumo: | Objective To explore the effects of hyaluronic acid (HA) on bleeding and associated outcomes after third molar extraction. Methods Forty patients who had undergone molar extraction were randomly divided into two groups; 0.8% (w/v) HA was applied to the HA group (n=20) whereas a control group (n=20) was not treated. Salivary and gingival tissue factor (TF) levels, bleeding time, maximum interincisal opening (MIO), pain scored on a visual analog scale (VAS), and the swelling extent were compared between the two groups. Results HA did not significantly affect gingival TF levels. Salivary TF levels increased significantly 1 week after HA application but not in the control group. Neither the VAS pain level nor MIO differed significantly between the two groups. The swelling extent on day 3 and the bleeding time were greater in the HA group than in the control group. Conclusions Local injection of HA at 0.8% prolonged the bleeding time, and increased hemorrhage and swelling in the early postoperative period after third molar extractions. |
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oai:revistas.usp.br:article/132892 |
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USP-17 |
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Journal of applied oral science (Online) |
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Effects of hyaluronic acid on bleeding following third molar extractionHyaluronic acidBleedingExtraction Objective To explore the effects of hyaluronic acid (HA) on bleeding and associated outcomes after third molar extraction. Methods Forty patients who had undergone molar extraction were randomly divided into two groups; 0.8% (w/v) HA was applied to the HA group (n=20) whereas a control group (n=20) was not treated. Salivary and gingival tissue factor (TF) levels, bleeding time, maximum interincisal opening (MIO), pain scored on a visual analog scale (VAS), and the swelling extent were compared between the two groups. Results HA did not significantly affect gingival TF levels. Salivary TF levels increased significantly 1 week after HA application but not in the control group. Neither the VAS pain level nor MIO differed significantly between the two groups. The swelling extent on day 3 and the bleeding time were greater in the HA group than in the control group. Conclusions Local injection of HA at 0.8% prolonged the bleeding time, and increased hemorrhage and swelling in the early postoperative period after third molar extractions.Universidade de São Paulo. Faculdade de Odontologia de Bauru2017-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/13289210.1590/1678-77572015-0187Journal of Applied Oral Science; Vol. 25 No. 2 (2017); 211-216Journal of Applied Oral Science; Vol. 25 Núm. 2 (2017); 211-216Journal of Applied Oral Science; v. 25 n. 2 (2017); 211-2161678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/132892/128960Copyright (c) 2017 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessGOCMEN, GokhanAKTOP, SertacTÜZÜNER, BurcinGOKER, BaharYARAT, Aysen2017-05-22T17:03:47Zoai:revistas.usp.br:article/132892Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2017-05-22T17:03:47Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Effects of hyaluronic acid on bleeding following third molar extraction |
title |
Effects of hyaluronic acid on bleeding following third molar extraction |
spellingShingle |
Effects of hyaluronic acid on bleeding following third molar extraction GOCMEN, Gokhan Hyaluronic acid Bleeding Extraction |
title_short |
Effects of hyaluronic acid on bleeding following third molar extraction |
title_full |
Effects of hyaluronic acid on bleeding following third molar extraction |
title_fullStr |
Effects of hyaluronic acid on bleeding following third molar extraction |
title_full_unstemmed |
Effects of hyaluronic acid on bleeding following third molar extraction |
title_sort |
Effects of hyaluronic acid on bleeding following third molar extraction |
author |
GOCMEN, Gokhan |
author_facet |
GOCMEN, Gokhan AKTOP, Sertac TÜZÜNER, Burcin GOKER, Bahar YARAT, Aysen |
author_role |
author |
author2 |
AKTOP, Sertac TÜZÜNER, Burcin GOKER, Bahar YARAT, Aysen |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
GOCMEN, Gokhan AKTOP, Sertac TÜZÜNER, Burcin GOKER, Bahar YARAT, Aysen |
dc.subject.por.fl_str_mv |
Hyaluronic acid Bleeding Extraction |
topic |
Hyaluronic acid Bleeding Extraction |
description |
Objective To explore the effects of hyaluronic acid (HA) on bleeding and associated outcomes after third molar extraction. Methods Forty patients who had undergone molar extraction were randomly divided into two groups; 0.8% (w/v) HA was applied to the HA group (n=20) whereas a control group (n=20) was not treated. Salivary and gingival tissue factor (TF) levels, bleeding time, maximum interincisal opening (MIO), pain scored on a visual analog scale (VAS), and the swelling extent were compared between the two groups. Results HA did not significantly affect gingival TF levels. Salivary TF levels increased significantly 1 week after HA application but not in the control group. Neither the VAS pain level nor MIO differed significantly between the two groups. The swelling extent on day 3 and the bleeding time were greater in the HA group than in the control group. Conclusions Local injection of HA at 0.8% prolonged the bleeding time, and increased hemorrhage and swelling in the early postoperative period after third molar extractions. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/132892 10.1590/1678-77572015-0187 |
url |
https://www.revistas.usp.br/jaos/article/view/132892 |
identifier_str_mv |
10.1590/1678-77572015-0187 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/132892/128960 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Journal of Applied Oral Science info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Journal of Applied Oral Science |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 25 No. 2 (2017); 211-216 Journal of Applied Oral Science; Vol. 25 Núm. 2 (2017); 211-216 Journal of Applied Oral Science; v. 25 n. 2 (2017); 211-216 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221680364158976 |