Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats

Detalhes bibliográficos
Autor(a) principal: Fernandes, Leandro Araújo
Data de Publicação: 2010
Outros Autores: Martins, Thiago Marchi, Almeida, Juliano Milanezi De, Nagata, Maria José Hitomi, Theodoro, Leticia Helena, Garcia, Valdir Gouveia, Bosco, Alvaro Francisco
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/3857
Resumo: OBJECTIVE: The aim of this study was to compare subgingival irrigation with tetracycline hydrochloride (TTC-HCL) as adjunctive treatment to scaling and root planning (SRP) on induced periodontitis in rats. MATERIAL AND METHODS: In 60 rats, periodontal disease was ligature-induced at the mandibular left first molar. After 7 days, the ligature was removed and all animals were submitted to SRP, and divided into 2 groups according to the following treatment: C (n=30) - subgingival irrigation with 1 mL of saline; T (n=30) - subgingival irrigation with 1 mL of TTC-HCL (50 mg/mL). Ten animals in each group were euthanized at 7, 15 and 30 days posttreatment. The histometric values were statistically analyzed (p
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spelling Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats IrrigationPeriodontal diseasesPeriodontitisRatsTetracycline OBJECTIVE: The aim of this study was to compare subgingival irrigation with tetracycline hydrochloride (TTC-HCL) as adjunctive treatment to scaling and root planning (SRP) on induced periodontitis in rats. MATERIAL AND METHODS: In 60 rats, periodontal disease was ligature-induced at the mandibular left first molar. After 7 days, the ligature was removed and all animals were submitted to SRP, and divided into 2 groups according to the following treatment: C (n=30) - subgingival irrigation with 1 mL of saline; T (n=30) - subgingival irrigation with 1 mL of TTC-HCL (50 mg/mL). Ten animals in each group were euthanized at 7, 15 and 30 days posttreatment. The histometric values were statistically analyzed (pUniversidade de São Paulo. Faculdade de Odontologia de Bauru2010-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/385710.1590/S1678-77572010000600017Journal of Applied Oral Science; Vol. 18 No. 6 (2010); 635-640 Journal of Applied Oral Science; Vol. 18 Núm. 6 (2010); 635-640 Journal of Applied Oral Science; v. 18 n. 6 (2010); 635-640 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3857/4547Copyright (c) 2010 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessFernandes, Leandro AraújoMartins, Thiago MarchiAlmeida, Juliano Milanezi DeNagata, Maria José HitomiTheodoro, Leticia HelenaGarcia, Valdir GouveiaBosco, Alvaro Francisco2012-04-27T12:11:52Zoai:revistas.usp.br:article/3857Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T12:11:52Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats
title Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats
spellingShingle Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats
Fernandes, Leandro Araújo
Irrigation
Periodontal diseases
Periodontitis
Rats
Tetracycline
title_short Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats
title_full Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats
title_fullStr Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats
title_full_unstemmed Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats
title_sort Experimental periodontal disease treatment by subgingival irrigation with tetracycline hydrochloride in rats
author Fernandes, Leandro Araújo
author_facet Fernandes, Leandro Araújo
Martins, Thiago Marchi
Almeida, Juliano Milanezi De
Nagata, Maria José Hitomi
Theodoro, Leticia Helena
Garcia, Valdir Gouveia
Bosco, Alvaro Francisco
author_role author
author2 Martins, Thiago Marchi
Almeida, Juliano Milanezi De
Nagata, Maria José Hitomi
Theodoro, Leticia Helena
Garcia, Valdir Gouveia
Bosco, Alvaro Francisco
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Fernandes, Leandro Araújo
Martins, Thiago Marchi
Almeida, Juliano Milanezi De
Nagata, Maria José Hitomi
Theodoro, Leticia Helena
Garcia, Valdir Gouveia
Bosco, Alvaro Francisco
dc.subject.por.fl_str_mv Irrigation
Periodontal diseases
Periodontitis
Rats
Tetracycline
topic Irrigation
Periodontal diseases
Periodontitis
Rats
Tetracycline
description OBJECTIVE: The aim of this study was to compare subgingival irrigation with tetracycline hydrochloride (TTC-HCL) as adjunctive treatment to scaling and root planning (SRP) on induced periodontitis in rats. MATERIAL AND METHODS: In 60 rats, periodontal disease was ligature-induced at the mandibular left first molar. After 7 days, the ligature was removed and all animals were submitted to SRP, and divided into 2 groups according to the following treatment: C (n=30) - subgingival irrigation with 1 mL of saline; T (n=30) - subgingival irrigation with 1 mL of TTC-HCL (50 mg/mL). Ten animals in each group were euthanized at 7, 15 and 30 days posttreatment. The histometric values were statistically analyzed (p
publishDate 2010
dc.date.none.fl_str_mv 2010-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3857
10.1590/S1678-77572010000600017
url https://www.revistas.usp.br/jaos/article/view/3857
identifier_str_mv 10.1590/S1678-77572010000600017
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3857/4547
dc.rights.driver.fl_str_mv Copyright (c) 2010 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2010 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 18 No. 6 (2010); 635-640
Journal of Applied Oral Science; Vol. 18 Núm. 6 (2010); 635-640
Journal of Applied Oral Science; v. 18 n. 6 (2010); 635-640
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
_version_ 1800221676146786304

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