Analysis of the antimicrobial and anti-caries effects of TiF4 varnish under microcosm biofilm formed on enamel

Detalhes bibliográficos
Autor(a) principal: Souza, Beatriz Martines de
Data de Publicação: 2018
Outros Autores: Fernandes Neto, Constantino, Salomão, Priscila Maria Aranda, Vasconcelos, Layla Reginna Silva Munhoz de, Andrade, Flaviana Bombarda de, Magalhães, Ana Carolina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/144552
Resumo: Titanium tetrafluoride (TiF4) is known for interacting with enamel reducing demineralization. However, no information is available about its potential antimicrobial effect. Objectives This study evaluated the antimicrobial and anti-caries potential of TiF4 varnish compared to NaF varnish, chlorhexidine gel (positive control), placebo varnish and untreated (negative controls) using a dental microcosm biofilm model. Material and Methods A microcosm biofilm was produced on bovine enamel previously treated with the varnishes, using inoculum from human saliva mixed with McBain saliva, under 0.2% sucrose exposure, for 14 days. All experiments were performed in biological triplicate (n=4/group in each experiment). Factors evaluated were: bacterial viability (% dead and live bacteria); CFU counting (log10 CFU/mL); and enamel demineralization (transverse microradiography – TMR). Data were analysed using ANOVA/Tukey's test or Kruskal-Wallis/Dunn's test (p
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spelling Analysis of the antimicrobial and anti-caries effects of TiF4 varnish under microcosm biofilm formed on enamelDental biofilmEnamel cariesFluorideTitaniumVarnish Titanium tetrafluoride (TiF4) is known for interacting with enamel reducing demineralization. However, no information is available about its potential antimicrobial effect. Objectives This study evaluated the antimicrobial and anti-caries potential of TiF4 varnish compared to NaF varnish, chlorhexidine gel (positive control), placebo varnish and untreated (negative controls) using a dental microcosm biofilm model. Material and Methods A microcosm biofilm was produced on bovine enamel previously treated with the varnishes, using inoculum from human saliva mixed with McBain saliva, under 0.2% sucrose exposure, for 14 days. All experiments were performed in biological triplicate (n=4/group in each experiment). Factors evaluated were: bacterial viability (% dead and live bacteria); CFU counting (log10 CFU/mL); and enamel demineralization (transverse microradiography – TMR). Data were analysed using ANOVA/Tukey's test or Kruskal-Wallis/Dunn's test (pUniversidade de São Paulo. Faculdade de Odontologia de Bauru2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/14455210.1590/1678-7757-2017-0304Journal of Applied Oral Science; Vol. 26 (2018); e20170304Journal of Applied Oral Science; Vol. 26 (2018); e20170304Journal of Applied Oral Science; v. 26 (2018); e201703041678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/144552/138875Copyright (c) 2018 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessSouza, Beatriz Martines deFernandes Neto, ConstantinoSalomão, Priscila Maria ArandaVasconcelos, Layla Reginna Silva Munhoz deAndrade, Flaviana Bombarda deMagalhães, Ana Carolina2018-03-20T12:30:07Zoai:revistas.usp.br:article/144552Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2018-03-20T12:30:07Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Analysis of the antimicrobial and anti-caries effects of TiF4 varnish under microcosm biofilm formed on enamel
title Analysis of the antimicrobial and anti-caries effects of TiF4 varnish under microcosm biofilm formed on enamel
spellingShingle Analysis of the antimicrobial and anti-caries effects of TiF4 varnish under microcosm biofilm formed on enamel
Souza, Beatriz Martines de
Dental biofilm
Enamel caries
Fluoride
Titanium
Varnish
title_short Analysis of the antimicrobial and anti-caries effects of TiF4 varnish under microcosm biofilm formed on enamel
title_full Analysis of the antimicrobial and anti-caries effects of TiF4 varnish under microcosm biofilm formed on enamel
title_fullStr Analysis of the antimicrobial and anti-caries effects of TiF4 varnish under microcosm biofilm formed on enamel
title_full_unstemmed Analysis of the antimicrobial and anti-caries effects of TiF4 varnish under microcosm biofilm formed on enamel
title_sort Analysis of the antimicrobial and anti-caries effects of TiF4 varnish under microcosm biofilm formed on enamel
author Souza, Beatriz Martines de
author_facet Souza, Beatriz Martines de
Fernandes Neto, Constantino
Salomão, Priscila Maria Aranda
Vasconcelos, Layla Reginna Silva Munhoz de
Andrade, Flaviana Bombarda de
Magalhães, Ana Carolina
author_role author
author2 Fernandes Neto, Constantino
Salomão, Priscila Maria Aranda
Vasconcelos, Layla Reginna Silva Munhoz de
Andrade, Flaviana Bombarda de
Magalhães, Ana Carolina
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Souza, Beatriz Martines de
Fernandes Neto, Constantino
Salomão, Priscila Maria Aranda
Vasconcelos, Layla Reginna Silva Munhoz de
Andrade, Flaviana Bombarda de
Magalhães, Ana Carolina
dc.subject.por.fl_str_mv Dental biofilm
Enamel caries
Fluoride
Titanium
Varnish
topic Dental biofilm
Enamel caries
Fluoride
Titanium
Varnish
description Titanium tetrafluoride (TiF4) is known for interacting with enamel reducing demineralization. However, no information is available about its potential antimicrobial effect. Objectives This study evaluated the antimicrobial and anti-caries potential of TiF4 varnish compared to NaF varnish, chlorhexidine gel (positive control), placebo varnish and untreated (negative controls) using a dental microcosm biofilm model. Material and Methods A microcosm biofilm was produced on bovine enamel previously treated with the varnishes, using inoculum from human saliva mixed with McBain saliva, under 0.2% sucrose exposure, for 14 days. All experiments were performed in biological triplicate (n=4/group in each experiment). Factors evaluated were: bacterial viability (% dead and live bacteria); CFU counting (log10 CFU/mL); and enamel demineralization (transverse microradiography – TMR). Data were analysed using ANOVA/Tukey's test or Kruskal-Wallis/Dunn's test (p
publishDate 2018
dc.date.none.fl_str_mv 2018-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/144552
10.1590/1678-7757-2017-0304
url https://www.revistas.usp.br/jaos/article/view/144552
identifier_str_mv 10.1590/1678-7757-2017-0304
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/144552/138875
dc.rights.driver.fl_str_mv Copyright (c) 2018 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 26 (2018); e20170304
Journal of Applied Oral Science; Vol. 26 (2018); e20170304
Journal of Applied Oral Science; v. 26 (2018); e20170304
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
_version_ 1800221681103405056

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