The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration

Detalhes bibliográficos
Autor(a) principal: Yildirim, Zuhal
Data de Publicação: 2011
Outros Autores: Ucgun, Nil Irem, Yildirim, Filiz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/19547
Resumo: OBJECTIVE: To investigate the role of oxidant/antioxidant status and protein oxidation in the development of age-related macular degeneration. METHOD: The activities of serum superoxide dismutase and glutathione peroxidase and the levels of serum malondialdehyde, advanced oxidation protein products, glutathione and vitamin C were measured in 25 patients with age-related macular degeneration and 25 control subjects without age-related macular degeneration. RESULT: The malondialdehyde and advanced oxidation protein product levels in the serum were significantly higher in the age-related macular degeneration patient group than in the control group (p
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spelling The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration Oxidative stressAntioxidantsProtein oxidationAMD OBJECTIVE: To investigate the role of oxidant/antioxidant status and protein oxidation in the development of age-related macular degeneration. METHOD: The activities of serum superoxide dismutase and glutathione peroxidase and the levels of serum malondialdehyde, advanced oxidation protein products, glutathione and vitamin C were measured in 25 patients with age-related macular degeneration and 25 control subjects without age-related macular degeneration. RESULT: The malondialdehyde and advanced oxidation protein product levels in the serum were significantly higher in the age-related macular degeneration patient group than in the control group (pHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1954710.1590/S1807-59322011000500006Clinics; Vol. 66 No. 5 (2011); 743-746 Clinics; v. 66 n. 5 (2011); 743-746 Clinics; Vol. 66 Núm. 5 (2011); 743-746 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/19547/21610Yildirim, ZuhalUcgun, Nil IremYildirim, Filizinfo:eu-repo/semantics/openAccess2012-05-23T16:47:59Zoai:revistas.usp.br:article/19547Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-23T16:47:59Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration
title The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration
spellingShingle The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration
Yildirim, Zuhal
Oxidative stress
Antioxidants
Protein oxidation
AMD
title_short The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration
title_full The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration
title_fullStr The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration
title_full_unstemmed The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration
title_sort The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration
author Yildirim, Zuhal
author_facet Yildirim, Zuhal
Ucgun, Nil Irem
Yildirim, Filiz
author_role author
author2 Ucgun, Nil Irem
Yildirim, Filiz
author2_role author
author
dc.contributor.author.fl_str_mv Yildirim, Zuhal
Ucgun, Nil Irem
Yildirim, Filiz
dc.subject.por.fl_str_mv Oxidative stress
Antioxidants
Protein oxidation
AMD
topic Oxidative stress
Antioxidants
Protein oxidation
AMD
description OBJECTIVE: To investigate the role of oxidant/antioxidant status and protein oxidation in the development of age-related macular degeneration. METHOD: The activities of serum superoxide dismutase and glutathione peroxidase and the levels of serum malondialdehyde, advanced oxidation protein products, glutathione and vitamin C were measured in 25 patients with age-related macular degeneration and 25 control subjects without age-related macular degeneration. RESULT: The malondialdehyde and advanced oxidation protein product levels in the serum were significantly higher in the age-related macular degeneration patient group than in the control group (p
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/19547
10.1590/S1807-59322011000500006
url https://www.revistas.usp.br/clinics/article/view/19547
identifier_str_mv 10.1590/S1807-59322011000500006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/19547/21610
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; Vol. 66 No. 5 (2011); 743-746
Clinics; v. 66 n. 5 (2011); 743-746
Clinics; Vol. 66 Núm. 5 (2011); 743-746
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clinics@hc.fm.usp.br
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