Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic Review
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/213014 |
Resumo: | Evidence shows that metabolic syndrome (MS) is associated with a greater risk of developing Parkinson’s disease (PD) because of the increase in oxidative stress levels along with other factors such as neuroinflammation and mitochondrial dysfunction. However, because some studies have reported that MS is associated with a lower risk of PD, the relationship between MS and PD should be investigated. This study aimed to investigate the effect of MS on PD. Two authors searched five electronic databases, namely, MEDLINE, PubMed, Scopus, PsycINFO, Web of Science, and Science Direct, for relevant articles between September and October 2020. After screening the title and abstract of all articles, 34 articles were selected for full-text review. Finally, 11 articles meeting the eligibility criteria were included in the study. The quality of articles was critically evaluated using the Joanna Briggs Institute. Overall, we evaluated data from 23,586,349 individuals (including healthy individuals, with MS and PD) aged 30 years or more. In cohort studies, the follow-up period varied between 2 and 30 years. MS contributed considerably to the increase in the incidence of PD. In addition, obesity, a component of MS, alone can increase the probability of developing neurodegenerative diseases. However, despite few studies on MS and PD, changes in cognitive function and more rapid progression of PD disease has been documented in patients with MS using methods commonly used in research. |
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Clinics |
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Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic ReviewMetabolic SyndromeParkinson DiseaseVascular Risk FactorsEvidence shows that metabolic syndrome (MS) is associated with a greater risk of developing Parkinson’s disease (PD) because of the increase in oxidative stress levels along with other factors such as neuroinflammation and mitochondrial dysfunction. However, because some studies have reported that MS is associated with a lower risk of PD, the relationship between MS and PD should be investigated. This study aimed to investigate the effect of MS on PD. Two authors searched five electronic databases, namely, MEDLINE, PubMed, Scopus, PsycINFO, Web of Science, and Science Direct, for relevant articles between September and October 2020. After screening the title and abstract of all articles, 34 articles were selected for full-text review. Finally, 11 articles meeting the eligibility criteria were included in the study. The quality of articles was critically evaluated using the Joanna Briggs Institute. Overall, we evaluated data from 23,586,349 individuals (including healthy individuals, with MS and PD) aged 30 years or more. In cohort studies, the follow-up period varied between 2 and 30 years. MS contributed considerably to the increase in the incidence of PD. In addition, obesity, a component of MS, alone can increase the probability of developing neurodegenerative diseases. However, despite few studies on MS and PD, changes in cognitive function and more rapid progression of PD disease has been documented in patients with MS using methods commonly used in research.Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2021-12-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/21301410.6061/clinics/2021/e3379Clinics; Vol. 76 (2021); e3379Clinics; v. 76 (2021); e3379Clinics; Vol. 76 (2021); e33791980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/213014/195032Copyright (c) 2023 Clinicsinfo:eu-repo/semantics/openAccessSouza, Ana Patrícia da SilvaBarros, Waleska Maria AlmeidaSilva, José Maurício LucasAna Beatriz Januário, Mariluce Rodrigues MarquesSilva, Ana Beatriz JanuárioFernandes, Matheus Santos de SousaSantos, Maria Eduarda Rodrigues Alves dosSilva, Mayara Luclécia daTaciane Silva doSilva, Roberta Karlize PereiraSilva, Karollainy Gomes daso, Sandra Lopes deSouza, Viviane de Oliveira Nogueira2023-07-06T13:04:09Zoai:revistas.usp.br:article/213014Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2023-07-06T13:04:09Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic Review |
title |
Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic Review |
spellingShingle |
Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic Review Souza, Ana Patrícia da Silva Metabolic Syndrome Parkinson Disease Vascular Risk Factors |
title_short |
Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic Review |
title_full |
Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic Review |
title_fullStr |
Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic Review |
title_full_unstemmed |
Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic Review |
title_sort |
Effect of Metabolic Syndrome on Parkinson’s Disease: A Systematic Review |
author |
Souza, Ana Patrícia da Silva |
author_facet |
Souza, Ana Patrícia da Silva Barros, Waleska Maria Almeida Silva, José Maurício Lucas Ana Beatriz Januário, Mariluce Rodrigues Marques Silva, Ana Beatriz Januário Fernandes, Matheus Santos de Sousa Santos, Maria Eduarda Rodrigues Alves dos Silva, Mayara Luclécia da Taciane Silva do Silva, Roberta Karlize Pereira Silva, Karollainy Gomes da so, Sandra Lopes de Souza, Viviane de Oliveira Nogueira |
author_role |
author |
author2 |
Barros, Waleska Maria Almeida Silva, José Maurício Lucas Ana Beatriz Januário, Mariluce Rodrigues Marques Silva, Ana Beatriz Januário Fernandes, Matheus Santos de Sousa Santos, Maria Eduarda Rodrigues Alves dos Silva, Mayara Luclécia da Taciane Silva do Silva, Roberta Karlize Pereira Silva, Karollainy Gomes da so, Sandra Lopes de Souza, Viviane de Oliveira Nogueira |
author2_role |
author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Souza, Ana Patrícia da Silva Barros, Waleska Maria Almeida Silva, José Maurício Lucas Ana Beatriz Januário, Mariluce Rodrigues Marques Silva, Ana Beatriz Januário Fernandes, Matheus Santos de Sousa Santos, Maria Eduarda Rodrigues Alves dos Silva, Mayara Luclécia da Taciane Silva do Silva, Roberta Karlize Pereira Silva, Karollainy Gomes da so, Sandra Lopes de Souza, Viviane de Oliveira Nogueira |
dc.subject.por.fl_str_mv |
Metabolic Syndrome Parkinson Disease Vascular Risk Factors |
topic |
Metabolic Syndrome Parkinson Disease Vascular Risk Factors |
description |
Evidence shows that metabolic syndrome (MS) is associated with a greater risk of developing Parkinson’s disease (PD) because of the increase in oxidative stress levels along with other factors such as neuroinflammation and mitochondrial dysfunction. However, because some studies have reported that MS is associated with a lower risk of PD, the relationship between MS and PD should be investigated. This study aimed to investigate the effect of MS on PD. Two authors searched five electronic databases, namely, MEDLINE, PubMed, Scopus, PsycINFO, Web of Science, and Science Direct, for relevant articles between September and October 2020. After screening the title and abstract of all articles, 34 articles were selected for full-text review. Finally, 11 articles meeting the eligibility criteria were included in the study. The quality of articles was critically evaluated using the Joanna Briggs Institute. Overall, we evaluated data from 23,586,349 individuals (including healthy individuals, with MS and PD) aged 30 years or more. In cohort studies, the follow-up period varied between 2 and 30 years. MS contributed considerably to the increase in the incidence of PD. In addition, obesity, a component of MS, alone can increase the probability of developing neurodegenerative diseases. However, despite few studies on MS and PD, changes in cognitive function and more rapid progression of PD disease has been documented in patients with MS using methods commonly used in research. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-12-13 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/213014 10.6061/clinics/2021/e3379 |
url |
https://www.revistas.usp.br/clinics/article/view/213014 |
identifier_str_mv |
10.6061/clinics/2021/e3379 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/213014/195032 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2023 Clinics info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2023 Clinics |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 76 (2021); e3379 Clinics; v. 76 (2021); e3379 Clinics; Vol. 76 (2021); e3379 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222766227521536 |