Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysis
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/19678 |
Resumo: | OBJECTIVE: The present study was designed to analyze the serum levels of aspartate and alanine aminotransferases, gamma-glutamyl transferase, and the hematocrit in patients with chronic kidney disease who were undergoing peritoneal dialysis or hemodialysis. PATIENTS AND METHODS: Twenty patients on peritoneal dialysis and 40 on hemodialysis were assessed, and the patients were matched according to the length of time that they had been on dialysis. Blood samples were collected (both before and after the session for those on hemodialysis) to measure the enzymes and the hematocrit. RESULTS: In the samples from the patients who were undergoing peritoneal dialysis, the aspartate and alanine aminotransferase levels were slightly higher compared with the samples collected from the patients before the hemodialysis session and slightly lower compared with the samples collected after the hemodialysis session. The levels of gamma-glutamyl transferase in the hemodialysis patients were slightly higher than the levels in the patients who were undergoing peritoneal dialysis. In addition, the levels of aminotransferases and gamma-glutamyl transferase that were collected before the hemodialysis session were significantly lower than the values collected after the session. The hematocrit levels were significantly lower in the patients who were on peritoneal dialysis compared with the patients on hemodialysis (both before and after the hemodialysis session), and the levels were also significantly lower before hemodialysis compared with after hemodialysis. CONCLUSION: The aminotransferase levels in the patients who were undergoing peritoneal dialysis were slightly higher compared with the samples collected before the hemodialysis session, whereas the aminotransferase levels were slightly lower compared with the samples collected after the session. The hematocrits and the aminotransferase and gamma-glutamyl transferase levels of the samples collected after the hemodialysis session were significantly higher than the samples collected before the session. Taken together, the present data suggest that hemodilution could alter the serum levels of liver enzymes. |
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Clinics |
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|
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Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysisAlanine aminotransferaseLiver enzymesHemodialysisPeritoneal dialysisChronic renal failureOBJECTIVE: The present study was designed to analyze the serum levels of aspartate and alanine aminotransferases, gamma-glutamyl transferase, and the hematocrit in patients with chronic kidney disease who were undergoing peritoneal dialysis or hemodialysis. PATIENTS AND METHODS: Twenty patients on peritoneal dialysis and 40 on hemodialysis were assessed, and the patients were matched according to the length of time that they had been on dialysis. Blood samples were collected (both before and after the session for those on hemodialysis) to measure the enzymes and the hematocrit. RESULTS: In the samples from the patients who were undergoing peritoneal dialysis, the aspartate and alanine aminotransferase levels were slightly higher compared with the samples collected from the patients before the hemodialysis session and slightly lower compared with the samples collected after the hemodialysis session. The levels of gamma-glutamyl transferase in the hemodialysis patients were slightly higher than the levels in the patients who were undergoing peritoneal dialysis. In addition, the levels of aminotransferases and gamma-glutamyl transferase that were collected before the hemodialysis session were significantly lower than the values collected after the session. The hematocrit levels were significantly lower in the patients who were on peritoneal dialysis compared with the patients on hemodialysis (both before and after the hemodialysis session), and the levels were also significantly lower before hemodialysis compared with after hemodialysis. CONCLUSION: The aminotransferase levels in the patients who were undergoing peritoneal dialysis were slightly higher compared with the samples collected before the hemodialysis session, whereas the aminotransferase levels were slightly lower compared with the samples collected after the session. The hematocrits and the aminotransferase and gamma-glutamyl transferase levels of the samples collected after the hemodialysis session were significantly higher than the samples collected before the session. Taken together, the present data suggest that hemodilution could alter the serum levels of liver enzymes.Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2012-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1967810.6061/clinics/2012(02)07Clinics; Vol. 67 No. 2 (2012); 131-134Clinics; v. 67 n. 2 (2012); 131-134Clinics; Vol. 67 Núm. 2 (2012); 131-1341980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/19678/21742Liberato, Isabella Ramos de OliveiraLopes, Edmundo Pessoa de AlmeidaCavalcante, Maria Alina Gomes de MattosPinto, Tiago CostaMoura, Izolda FernadesLoureiro Júnior, Luizinfo:eu-repo/semantics/openAccess2012-05-24T18:50:37Zoai:revistas.usp.br:article/19678Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-24T18:50:37Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysis |
title |
Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysis |
spellingShingle |
Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysis Liberato, Isabella Ramos de Oliveira Alanine aminotransferase Liver enzymes Hemodialysis Peritoneal dialysis Chronic renal failure |
title_short |
Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysis |
title_full |
Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysis |
title_fullStr |
Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysis |
title_full_unstemmed |
Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysis |
title_sort |
Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysis |
author |
Liberato, Isabella Ramos de Oliveira |
author_facet |
Liberato, Isabella Ramos de Oliveira Lopes, Edmundo Pessoa de Almeida Cavalcante, Maria Alina Gomes de Mattos Pinto, Tiago Costa Moura, Izolda Fernades Loureiro Júnior, Luiz |
author_role |
author |
author2 |
Lopes, Edmundo Pessoa de Almeida Cavalcante, Maria Alina Gomes de Mattos Pinto, Tiago Costa Moura, Izolda Fernades Loureiro Júnior, Luiz |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Liberato, Isabella Ramos de Oliveira Lopes, Edmundo Pessoa de Almeida Cavalcante, Maria Alina Gomes de Mattos Pinto, Tiago Costa Moura, Izolda Fernades Loureiro Júnior, Luiz |
dc.subject.por.fl_str_mv |
Alanine aminotransferase Liver enzymes Hemodialysis Peritoneal dialysis Chronic renal failure |
topic |
Alanine aminotransferase Liver enzymes Hemodialysis Peritoneal dialysis Chronic renal failure |
description |
OBJECTIVE: The present study was designed to analyze the serum levels of aspartate and alanine aminotransferases, gamma-glutamyl transferase, and the hematocrit in patients with chronic kidney disease who were undergoing peritoneal dialysis or hemodialysis. PATIENTS AND METHODS: Twenty patients on peritoneal dialysis and 40 on hemodialysis were assessed, and the patients were matched according to the length of time that they had been on dialysis. Blood samples were collected (both before and after the session for those on hemodialysis) to measure the enzymes and the hematocrit. RESULTS: In the samples from the patients who were undergoing peritoneal dialysis, the aspartate and alanine aminotransferase levels were slightly higher compared with the samples collected from the patients before the hemodialysis session and slightly lower compared with the samples collected after the hemodialysis session. The levels of gamma-glutamyl transferase in the hemodialysis patients were slightly higher than the levels in the patients who were undergoing peritoneal dialysis. In addition, the levels of aminotransferases and gamma-glutamyl transferase that were collected before the hemodialysis session were significantly lower than the values collected after the session. The hematocrit levels were significantly lower in the patients who were on peritoneal dialysis compared with the patients on hemodialysis (both before and after the hemodialysis session), and the levels were also significantly lower before hemodialysis compared with after hemodialysis. CONCLUSION: The aminotransferase levels in the patients who were undergoing peritoneal dialysis were slightly higher compared with the samples collected before the hemodialysis session, whereas the aminotransferase levels were slightly lower compared with the samples collected after the session. The hematocrits and the aminotransferase and gamma-glutamyl transferase levels of the samples collected after the hemodialysis session were significantly higher than the samples collected before the session. Taken together, the present data suggest that hemodilution could alter the serum levels of liver enzymes. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/19678 10.6061/clinics/2012(02)07 |
url |
https://www.revistas.usp.br/clinics/article/view/19678 |
identifier_str_mv |
10.6061/clinics/2012(02)07 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/19678/21742 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 67 No. 2 (2012); 131-134 Clinics; v. 67 n. 2 (2012); 131-134 Clinics; Vol. 67 Núm. 2 (2012); 131-134 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222758238420992 |