Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/19517 |
Resumo: | OBJECTIVE: To describe nutritional status, body composition and lipid profile in children and adolescents receiving protease inhibitors. METHODS: Fifty-nine patients, 23 treated with protease inhibitors (group 1) and 36 not using protease inhibitors (group 2). Their dietary intake, anthropometry, bioimpedance analysis and lipid profile variables were measured. RESULTS: There was no difference in nutritional status or body composition between groups at the beginning of the study. After 6 months of follow-up, there was an increase in weight and height in both groups, as well as in waist circumference and subscapular skinfold thickness. In group 2, body mass index and triceps skinfold thickness adequacy were significantly higher after 6 months of follow-up. The groups had similar energy and macronutrient intake at any time point. After 6 months, group 1 had a higher cholesterol intake and group 2 had a higher fiber intake. Triglyceride serum levels were significantly different between the groups, with higher values in G1, at any time point [G1: 153 mg/dl (30-344); 138 (58-378) versus G2: 76 mg/dl (29-378); 76 (29-378)]. After 6 months of follow-up, G1 had higher LDL-cholesterol than G2 [104 mg/dl (40-142) versus 82 (42-145)]. CONCLUSION: The use of protease inhibitors, per se, does not seem to significantly interfere with anthropometric measures, body composition and food intake of HIV-infected children and adolescents. However, this antiretroviral therapy was associated with a significant increase in triglyceride and LDL-cholesterol in our subjects. |
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Clinics |
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Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy Children and adolescentsHIVProtease inhibitorDyslipidemiaNutritional status OBJECTIVE: To describe nutritional status, body composition and lipid profile in children and adolescents receiving protease inhibitors. METHODS: Fifty-nine patients, 23 treated with protease inhibitors (group 1) and 36 not using protease inhibitors (group 2). Their dietary intake, anthropometry, bioimpedance analysis and lipid profile variables were measured. RESULTS: There was no difference in nutritional status or body composition between groups at the beginning of the study. After 6 months of follow-up, there was an increase in weight and height in both groups, as well as in waist circumference and subscapular skinfold thickness. In group 2, body mass index and triceps skinfold thickness adequacy were significantly higher after 6 months of follow-up. The groups had similar energy and macronutrient intake at any time point. After 6 months, group 1 had a higher cholesterol intake and group 2 had a higher fiber intake. Triglyceride serum levels were significantly different between the groups, with higher values in G1, at any time point [G1: 153 mg/dl (30-344); 138 (58-378) versus G2: 76 mg/dl (29-378); 76 (29-378)]. After 6 months of follow-up, G1 had higher LDL-cholesterol than G2 [104 mg/dl (40-142) versus 82 (42-145)]. CONCLUSION: The use of protease inhibitors, per se, does not seem to significantly interfere with anthropometric measures, body composition and food intake of HIV-infected children and adolescents. However, this antiretroviral therapy was associated with a significant increase in triglyceride and LDL-cholesterol in our subjects. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1951710.1590/S1807-59322011000600013Clinics; v. 66 n. 6 (2011); 997-1002 Clinics; Vol. 66 Núm. 6 (2011); 997-1002 Clinics; Vol. 66 No. 6 (2011); 997-1002 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/19517/21580Contri, Patricia ViganóBerchielli, Érica MirandaTremeschin, Marina HjertquistNegrini, Bento Vidal de MouraSalomão, Roberta GarciaMonteiro, Jacqueline Pontesinfo:eu-repo/semantics/openAccess2012-05-23T16:46:07Zoai:revistas.usp.br:article/19517Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-23T16:46:07Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy |
title |
Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy |
spellingShingle |
Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy Contri, Patricia Viganó Children and adolescents HIV Protease inhibitor Dyslipidemia Nutritional status |
title_short |
Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy |
title_full |
Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy |
title_fullStr |
Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy |
title_full_unstemmed |
Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy |
title_sort |
Nutritional status and lipid profile of HIV-positive children and adolescents using antiretroviral therapy |
author |
Contri, Patricia Viganó |
author_facet |
Contri, Patricia Viganó Berchielli, Érica Miranda Tremeschin, Marina Hjertquist Negrini, Bento Vidal de Moura Salomão, Roberta Garcia Monteiro, Jacqueline Pontes |
author_role |
author |
author2 |
Berchielli, Érica Miranda Tremeschin, Marina Hjertquist Negrini, Bento Vidal de Moura Salomão, Roberta Garcia Monteiro, Jacqueline Pontes |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Contri, Patricia Viganó Berchielli, Érica Miranda Tremeschin, Marina Hjertquist Negrini, Bento Vidal de Moura Salomão, Roberta Garcia Monteiro, Jacqueline Pontes |
dc.subject.por.fl_str_mv |
Children and adolescents HIV Protease inhibitor Dyslipidemia Nutritional status |
topic |
Children and adolescents HIV Protease inhibitor Dyslipidemia Nutritional status |
description |
OBJECTIVE: To describe nutritional status, body composition and lipid profile in children and adolescents receiving protease inhibitors. METHODS: Fifty-nine patients, 23 treated with protease inhibitors (group 1) and 36 not using protease inhibitors (group 2). Their dietary intake, anthropometry, bioimpedance analysis and lipid profile variables were measured. RESULTS: There was no difference in nutritional status or body composition between groups at the beginning of the study. After 6 months of follow-up, there was an increase in weight and height in both groups, as well as in waist circumference and subscapular skinfold thickness. In group 2, body mass index and triceps skinfold thickness adequacy were significantly higher after 6 months of follow-up. The groups had similar energy and macronutrient intake at any time point. After 6 months, group 1 had a higher cholesterol intake and group 2 had a higher fiber intake. Triglyceride serum levels were significantly different between the groups, with higher values in G1, at any time point [G1: 153 mg/dl (30-344); 138 (58-378) versus G2: 76 mg/dl (29-378); 76 (29-378)]. After 6 months of follow-up, G1 had higher LDL-cholesterol than G2 [104 mg/dl (40-142) versus 82 (42-145)]. CONCLUSION: The use of protease inhibitors, per se, does not seem to significantly interfere with anthropometric measures, body composition and food intake of HIV-infected children and adolescents. However, this antiretroviral therapy was associated with a significant increase in triglyceride and LDL-cholesterol in our subjects. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/19517 10.1590/S1807-59322011000600013 |
url |
https://www.revistas.usp.br/clinics/article/view/19517 |
identifier_str_mv |
10.1590/S1807-59322011000600013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/19517/21580 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; v. 66 n. 6 (2011); 997-1002 Clinics; Vol. 66 Núm. 6 (2011); 997-1002 Clinics; Vol. 66 No. 6 (2011); 997-1002 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1787713174013739008 |