Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children

Detalhes bibliográficos
Autor(a) principal: Zhang, Zuojuan
Data de Publicação: 2016
Outros Autores: Wang, Juandong, Ji, Buqiang, Bahr Greenwood, Tatiana von, Zhang, Yuan, Wang, Yongjing, Kong, Dexiao, Li, Ai, Jiang, Yang, Guo, Yanan, Liu, Xiaoli, Wang, Yingxue, Dou, Aixia, Li, Nailin, Henter, Jan-Inge, Sun, Guizhen, Zheng, Chengyun
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/115294
Resumo: OBJECTIVE: Hemophagocytic lymphohistiocytosis in adults is largely underdiagnosed. To improve the rate and accuracy of diagnosis in adults, the clinical and laboratory characteristics of hemophagocytic lymphohistiocytosis were analyzed in and compared between adults and children in a Chinese cohort. METHOD: Data from 50 hemophagocytic lymphohistiocytosis patients, including 34 adults and 16 children who fulfilled the 2004 hemophagocytic lymphohistiocytosis diagnostic criteria, were collected and analyzed. RESULTS: 1. Etiological factors: The proportion of Epstein-Barr virus infection was lower in adults compared with children, whereas fungal infection and natural killer/T cell lymphoma were more frequent in adults (P
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spelling Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children OBJECTIVE: Hemophagocytic lymphohistiocytosis in adults is largely underdiagnosed. To improve the rate and accuracy of diagnosis in adults, the clinical and laboratory characteristics of hemophagocytic lymphohistiocytosis were analyzed in and compared between adults and children in a Chinese cohort. METHOD: Data from 50 hemophagocytic lymphohistiocytosis patients, including 34 adults and 16 children who fulfilled the 2004 hemophagocytic lymphohistiocytosis diagnostic criteria, were collected and analyzed. RESULTS: 1. Etiological factors: The proportion of Epstein-Barr virus infection was lower in adults compared with children, whereas fungal infection and natural killer/T cell lymphoma were more frequent in adults (PHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2016-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/11529410.6061/clinics/2016(04)05Clinics; Vol. 71 No. 4 (2016); 205-209Clinics; v. 71 n. 4 (2016); 205-209Clinics; Vol. 71 Núm. 4 (2016); 205-2091980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/115294/112975Copyright (c) 2016 Clinicsinfo:eu-repo/semantics/openAccessZhang, ZuojuanWang, JuandongJi, BuqiangBahr Greenwood, Tatiana vonZhang, YuanWang, YongjingKong, DexiaoLi, AiJiang, YangGuo, YananLiu, XiaoliWang, YingxueDou, AixiaLi, NailinHenter, Jan-IngeSun, GuizhenZheng, Chengyun2016-05-10T19:36:01Zoai:revistas.usp.br:article/115294Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2016-05-10T19:36:01Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children
title Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children
spellingShingle Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children
Zhang, Zuojuan
title_short Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children
title_full Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children
title_fullStr Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children
title_full_unstemmed Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children
title_sort Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children
author Zhang, Zuojuan
author_facet Zhang, Zuojuan
Wang, Juandong
Ji, Buqiang
Bahr Greenwood, Tatiana von
Zhang, Yuan
Wang, Yongjing
Kong, Dexiao
Li, Ai
Jiang, Yang
Guo, Yanan
Liu, Xiaoli
Wang, Yingxue
Dou, Aixia
Li, Nailin
Henter, Jan-Inge
Sun, Guizhen
Zheng, Chengyun
author_role author
author2 Wang, Juandong
Ji, Buqiang
Bahr Greenwood, Tatiana von
Zhang, Yuan
Wang, Yongjing
Kong, Dexiao
Li, Ai
Jiang, Yang
Guo, Yanan
Liu, Xiaoli
Wang, Yingxue
Dou, Aixia
Li, Nailin
Henter, Jan-Inge
Sun, Guizhen
Zheng, Chengyun
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Zhang, Zuojuan
Wang, Juandong
Ji, Buqiang
Bahr Greenwood, Tatiana von
Zhang, Yuan
Wang, Yongjing
Kong, Dexiao
Li, Ai
Jiang, Yang
Guo, Yanan
Liu, Xiaoli
Wang, Yingxue
Dou, Aixia
Li, Nailin
Henter, Jan-Inge
Sun, Guizhen
Zheng, Chengyun
description OBJECTIVE: Hemophagocytic lymphohistiocytosis in adults is largely underdiagnosed. To improve the rate and accuracy of diagnosis in adults, the clinical and laboratory characteristics of hemophagocytic lymphohistiocytosis were analyzed in and compared between adults and children in a Chinese cohort. METHOD: Data from 50 hemophagocytic lymphohistiocytosis patients, including 34 adults and 16 children who fulfilled the 2004 hemophagocytic lymphohistiocytosis diagnostic criteria, were collected and analyzed. RESULTS: 1. Etiological factors: The proportion of Epstein-Barr virus infection was lower in adults compared with children, whereas fungal infection and natural killer/T cell lymphoma were more frequent in adults (P
publishDate 2016
dc.date.none.fl_str_mv 2016-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/115294
10.6061/clinics/2016(04)05
url https://www.revistas.usp.br/clinics/article/view/115294
identifier_str_mv 10.6061/clinics/2016(04)05
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/115294/112975
dc.rights.driver.fl_str_mv Copyright (c) 2016 Clinics
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2016 Clinics
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; Vol. 71 No. 4 (2016); 205-209
Clinics; v. 71 n. 4 (2016); 205-209
Clinics; Vol. 71 Núm. 4 (2016); 205-209
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clinics@hc.fm.usp.br
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