Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/115294 |
Resumo: | OBJECTIVE: Hemophagocytic lymphohistiocytosis in adults is largely underdiagnosed. To improve the rate and accuracy of diagnosis in adults, the clinical and laboratory characteristics of hemophagocytic lymphohistiocytosis were analyzed in and compared between adults and children in a Chinese cohort. METHOD: Data from 50 hemophagocytic lymphohistiocytosis patients, including 34 adults and 16 children who fulfilled the 2004 hemophagocytic lymphohistiocytosis diagnostic criteria, were collected and analyzed. RESULTS: 1. Etiological factors: The proportion of Epstein-Barr virus infection was lower in adults compared with children, whereas fungal infection and natural killer/T cell lymphoma were more frequent in adults (P |
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oai:revistas.usp.br:article/115294 |
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USP-19 |
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Clinics |
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Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children OBJECTIVE: Hemophagocytic lymphohistiocytosis in adults is largely underdiagnosed. To improve the rate and accuracy of diagnosis in adults, the clinical and laboratory characteristics of hemophagocytic lymphohistiocytosis were analyzed in and compared between adults and children in a Chinese cohort. METHOD: Data from 50 hemophagocytic lymphohistiocytosis patients, including 34 adults and 16 children who fulfilled the 2004 hemophagocytic lymphohistiocytosis diagnostic criteria, were collected and analyzed. RESULTS: 1. Etiological factors: The proportion of Epstein-Barr virus infection was lower in adults compared with children, whereas fungal infection and natural killer/T cell lymphoma were more frequent in adults (PHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2016-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/11529410.6061/clinics/2016(04)05Clinics; Vol. 71 No. 4 (2016); 205-209Clinics; v. 71 n. 4 (2016); 205-209Clinics; Vol. 71 Núm. 4 (2016); 205-2091980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/115294/112975Copyright (c) 2016 Clinicsinfo:eu-repo/semantics/openAccessZhang, ZuojuanWang, JuandongJi, BuqiangBahr Greenwood, Tatiana vonZhang, YuanWang, YongjingKong, DexiaoLi, AiJiang, YangGuo, YananLiu, XiaoliWang, YingxueDou, AixiaLi, NailinHenter, Jan-IngeSun, GuizhenZheng, Chengyun2016-05-10T19:36:01Zoai:revistas.usp.br:article/115294Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2016-05-10T19:36:01Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children |
title |
Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children |
spellingShingle |
Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children Zhang, Zuojuan |
title_short |
Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children |
title_full |
Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children |
title_fullStr |
Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children |
title_full_unstemmed |
Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children |
title_sort |
Clinical presentation of hemophagocytic lymphohistiocytosis in adults is less typical than in children |
author |
Zhang, Zuojuan |
author_facet |
Zhang, Zuojuan Wang, Juandong Ji, Buqiang Bahr Greenwood, Tatiana von Zhang, Yuan Wang, Yongjing Kong, Dexiao Li, Ai Jiang, Yang Guo, Yanan Liu, Xiaoli Wang, Yingxue Dou, Aixia Li, Nailin Henter, Jan-Inge Sun, Guizhen Zheng, Chengyun |
author_role |
author |
author2 |
Wang, Juandong Ji, Buqiang Bahr Greenwood, Tatiana von Zhang, Yuan Wang, Yongjing Kong, Dexiao Li, Ai Jiang, Yang Guo, Yanan Liu, Xiaoli Wang, Yingxue Dou, Aixia Li, Nailin Henter, Jan-Inge Sun, Guizhen Zheng, Chengyun |
author2_role |
author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Zhang, Zuojuan Wang, Juandong Ji, Buqiang Bahr Greenwood, Tatiana von Zhang, Yuan Wang, Yongjing Kong, Dexiao Li, Ai Jiang, Yang Guo, Yanan Liu, Xiaoli Wang, Yingxue Dou, Aixia Li, Nailin Henter, Jan-Inge Sun, Guizhen Zheng, Chengyun |
description |
OBJECTIVE: Hemophagocytic lymphohistiocytosis in adults is largely underdiagnosed. To improve the rate and accuracy of diagnosis in adults, the clinical and laboratory characteristics of hemophagocytic lymphohistiocytosis were analyzed in and compared between adults and children in a Chinese cohort. METHOD: Data from 50 hemophagocytic lymphohistiocytosis patients, including 34 adults and 16 children who fulfilled the 2004 hemophagocytic lymphohistiocytosis diagnostic criteria, were collected and analyzed. RESULTS: 1. Etiological factors: The proportion of Epstein-Barr virus infection was lower in adults compared with children, whereas fungal infection and natural killer/T cell lymphoma were more frequent in adults (P |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/115294 10.6061/clinics/2016(04)05 |
url |
https://www.revistas.usp.br/clinics/article/view/115294 |
identifier_str_mv |
10.6061/clinics/2016(04)05 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/115294/112975 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2016 Clinics info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2016 Clinics |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 71 No. 4 (2016); 205-209 Clinics; v. 71 n. 4 (2016); 205-209 Clinics; Vol. 71 Núm. 4 (2016); 205-209 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222762595254272 |