Effect of renal embolization with trisacryl and PAVc
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/18075 |
Resumo: | OBJECTIVES: Evaluate the degree of vascular occlusion, vascular recanalization, and necrosis of the vascular wall caused by polyvinyl alcohol-covered polyvinyl acetate (PVAc) particles compared to trisacryl particles after renal embolization. METHODS: Seventy-nine female albino New Zealand rabbits underwent arterial catheterization of the right kidney. Thirty-three animals were embolized with trisacryl particles, thirty-one with PVAc particles, and fifteen were kept as controls. Four animals were excluded (three trisacryl and one PVAc) due to early death. Five subgroups of six animals were created. The animals in the different groups were sacrificed either 48 hours, 5 days, 10 days, 30 days, or 90 days after embolization. The control group was divided into subgroups of three animals each and kept for the same periods of time. The kidneys were dyed with hematoxylin-eosin and Masson's trichrome and then examined using optical microscopy. RESULTS: There were significant differences in the degree of vascular occlusion caused by the trisacryl and the PVAc particles between the five-day and the ten-day groups. Additional differences were noted between the five-day and 48-hour groups in regard to the amount of necrosis. For both findings, the PVAc group members showed adequate tissue reaction (ischemia and volumetric reduction) and less recanalization than those treated with trisacryl. CONCLUSION: The use of PVAc as an embolization material exhibited an adequate tissue reaction (ischemia and volumetric reduction), more expressive vascular occlusion and necrosis, and less recanalization than the trisacryl material. |
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Clinics |
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Effect of renal embolization with trisacryl and PAVc Therapeutic embolizationParticlesMicrospheresInterventional radiologyKidney OBJECTIVES: Evaluate the degree of vascular occlusion, vascular recanalization, and necrosis of the vascular wall caused by polyvinyl alcohol-covered polyvinyl acetate (PVAc) particles compared to trisacryl particles after renal embolization. METHODS: Seventy-nine female albino New Zealand rabbits underwent arterial catheterization of the right kidney. Thirty-three animals were embolized with trisacryl particles, thirty-one with PVAc particles, and fifteen were kept as controls. Four animals were excluded (three trisacryl and one PVAc) due to early death. Five subgroups of six animals were created. The animals in the different groups were sacrificed either 48 hours, 5 days, 10 days, 30 days, or 90 days after embolization. The control group was divided into subgroups of three animals each and kept for the same periods of time. The kidneys were dyed with hematoxylin-eosin and Masson's trichrome and then examined using optical microscopy. RESULTS: There were significant differences in the degree of vascular occlusion caused by the trisacryl and the PVAc particles between the five-day and the ten-day groups. Additional differences were noted between the five-day and 48-hour groups in regard to the amount of necrosis. For both findings, the PVAc group members showed adequate tissue reaction (ischemia and volumetric reduction) and less recanalization than those treated with trisacryl. CONCLUSION: The use of PVAc as an embolization material exhibited an adequate tissue reaction (ischemia and volumetric reduction), more expressive vascular occlusion and necrosis, and less recanalization than the trisacryl material. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2009-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1807510.1590/S1807-59322009001100011Clinics; Vol. 64 No. 11 (2009); 1105-1112 Clinics; v. 64 n. 11 (2009); 1105-1112 Clinics; Vol. 64 Núm. 11 (2009); 1105-1112 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/18075/20139Barbosa, Leandro de AssisCaldas, Jose Guilherme Mendes PereiraConti, Mario LuizMalheiros, Denise Maria Avancini CostaRamos Jr., Francisco Ferreirainfo:eu-repo/semantics/openAccess2012-05-22T18:54:34Zoai:revistas.usp.br:article/18075Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-22T18:54:34Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Effect of renal embolization with trisacryl and PAVc |
title |
Effect of renal embolization with trisacryl and PAVc |
spellingShingle |
Effect of renal embolization with trisacryl and PAVc Barbosa, Leandro de Assis Therapeutic embolization Particles Microspheres Interventional radiology Kidney |
title_short |
Effect of renal embolization with trisacryl and PAVc |
title_full |
Effect of renal embolization with trisacryl and PAVc |
title_fullStr |
Effect of renal embolization with trisacryl and PAVc |
title_full_unstemmed |
Effect of renal embolization with trisacryl and PAVc |
title_sort |
Effect of renal embolization with trisacryl and PAVc |
author |
Barbosa, Leandro de Assis |
author_facet |
Barbosa, Leandro de Assis Caldas, Jose Guilherme Mendes Pereira Conti, Mario Luiz Malheiros, Denise Maria Avancini Costa Ramos Jr., Francisco Ferreira |
author_role |
author |
author2 |
Caldas, Jose Guilherme Mendes Pereira Conti, Mario Luiz Malheiros, Denise Maria Avancini Costa Ramos Jr., Francisco Ferreira |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Barbosa, Leandro de Assis Caldas, Jose Guilherme Mendes Pereira Conti, Mario Luiz Malheiros, Denise Maria Avancini Costa Ramos Jr., Francisco Ferreira |
dc.subject.por.fl_str_mv |
Therapeutic embolization Particles Microspheres Interventional radiology Kidney |
topic |
Therapeutic embolization Particles Microspheres Interventional radiology Kidney |
description |
OBJECTIVES: Evaluate the degree of vascular occlusion, vascular recanalization, and necrosis of the vascular wall caused by polyvinyl alcohol-covered polyvinyl acetate (PVAc) particles compared to trisacryl particles after renal embolization. METHODS: Seventy-nine female albino New Zealand rabbits underwent arterial catheterization of the right kidney. Thirty-three animals were embolized with trisacryl particles, thirty-one with PVAc particles, and fifteen were kept as controls. Four animals were excluded (three trisacryl and one PVAc) due to early death. Five subgroups of six animals were created. The animals in the different groups were sacrificed either 48 hours, 5 days, 10 days, 30 days, or 90 days after embolization. The control group was divided into subgroups of three animals each and kept for the same periods of time. The kidneys were dyed with hematoxylin-eosin and Masson's trichrome and then examined using optical microscopy. RESULTS: There were significant differences in the degree of vascular occlusion caused by the trisacryl and the PVAc particles between the five-day and the ten-day groups. Additional differences were noted between the five-day and 48-hour groups in regard to the amount of necrosis. For both findings, the PVAc group members showed adequate tissue reaction (ischemia and volumetric reduction) and less recanalization than those treated with trisacryl. CONCLUSION: The use of PVAc as an embolization material exhibited an adequate tissue reaction (ischemia and volumetric reduction), more expressive vascular occlusion and necrosis, and less recanalization than the trisacryl material. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/18075 10.1590/S1807-59322009001100011 |
url |
https://www.revistas.usp.br/clinics/article/view/18075 |
identifier_str_mv |
10.1590/S1807-59322009001100011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/18075/20139 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 64 No. 11 (2009); 1105-1112 Clinics; v. 64 n. 11 (2009); 1105-1112 Clinics; Vol. 64 Núm. 11 (2009); 1105-1112 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222754811674624 |