Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/45863 |
Resumo: | OBJECTIVES: Although individuals with Down syndrome have considerable oral disease, the prevalence of dental caries in this group is low. The present study aimed to compare known risk factors for dental caries development in children with Down syndrome and a matched population (siblings). In both populations, the number of acidogenic microorganisms, such as mutans streptococci, lactobacilli and Candida species, and the paraffin-stimulated pH, flow rate and IgA concentration in whole saliva were evaluated and compared. METHOD: Saliva was collected, and the caries index was evaluated in 45 sibling pairs aged between 6 and 18 years old. The salivary IgA concentration was determined by immunoturbidimetry. Salivary mutans streptococci, lactobacilli and Candida species were quantified on mitis salivarius agar containing bacitracin and 20% sucrose, rogosa agar supplemented with glacial acetic acid and sabouraud agar supplemented with chloramphenicol, respectively. RESULTS: Down syndrome children had a higher caries-free rate (p |
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Clinics |
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Reduced salivary flow and colonization by mutans streptococci in children with Down syndromeDown SyndromeStreptococcus MutansImmunoglobulin AXerostomiaOBJECTIVES: Although individuals with Down syndrome have considerable oral disease, the prevalence of dental caries in this group is low. The present study aimed to compare known risk factors for dental caries development in children with Down syndrome and a matched population (siblings). In both populations, the number of acidogenic microorganisms, such as mutans streptococci, lactobacilli and Candida species, and the paraffin-stimulated pH, flow rate and IgA concentration in whole saliva were evaluated and compared. METHOD: Saliva was collected, and the caries index was evaluated in 45 sibling pairs aged between 6 and 18 years old. The salivary IgA concentration was determined by immunoturbidimetry. Salivary mutans streptococci, lactobacilli and Candida species were quantified on mitis salivarius agar containing bacitracin and 20% sucrose, rogosa agar supplemented with glacial acetic acid and sabouraud agar supplemented with chloramphenicol, respectively. RESULTS: Down syndrome children had a higher caries-free rate (pHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2012-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/4586310.6061/clinics/2012(09)04Clinics; Vol. 67 No. 9 (2012); 1007-1011Clinics; v. 67 n. 9 (2012); 1007-1011Clinics; Vol. 67 Núm. 9 (2012); 1007-10111980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/45863/49466Areias, CristinaSampaio-Maia, BeneditaPereira, Maria de LurdesAzevedo, AlvaroMelo, PauloAndrade, CasimiroScully, Crispianinfo:eu-repo/semantics/openAccess2012-10-10T20:41:55Zoai:revistas.usp.br:article/45863Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-10-10T20:41:55Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome |
title |
Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome |
spellingShingle |
Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome Areias, Cristina Down Syndrome Streptococcus Mutans Immunoglobulin A Xerostomia |
title_short |
Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome |
title_full |
Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome |
title_fullStr |
Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome |
title_full_unstemmed |
Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome |
title_sort |
Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome |
author |
Areias, Cristina |
author_facet |
Areias, Cristina Sampaio-Maia, Benedita Pereira, Maria de Lurdes Azevedo, Alvaro Melo, Paulo Andrade, Casimiro Scully, Crispian |
author_role |
author |
author2 |
Sampaio-Maia, Benedita Pereira, Maria de Lurdes Azevedo, Alvaro Melo, Paulo Andrade, Casimiro Scully, Crispian |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Areias, Cristina Sampaio-Maia, Benedita Pereira, Maria de Lurdes Azevedo, Alvaro Melo, Paulo Andrade, Casimiro Scully, Crispian |
dc.subject.por.fl_str_mv |
Down Syndrome Streptococcus Mutans Immunoglobulin A Xerostomia |
topic |
Down Syndrome Streptococcus Mutans Immunoglobulin A Xerostomia |
description |
OBJECTIVES: Although individuals with Down syndrome have considerable oral disease, the prevalence of dental caries in this group is low. The present study aimed to compare known risk factors for dental caries development in children with Down syndrome and a matched population (siblings). In both populations, the number of acidogenic microorganisms, such as mutans streptococci, lactobacilli and Candida species, and the paraffin-stimulated pH, flow rate and IgA concentration in whole saliva were evaluated and compared. METHOD: Saliva was collected, and the caries index was evaluated in 45 sibling pairs aged between 6 and 18 years old. The salivary IgA concentration was determined by immunoturbidimetry. Salivary mutans streptococci, lactobacilli and Candida species were quantified on mitis salivarius agar containing bacitracin and 20% sucrose, rogosa agar supplemented with glacial acetic acid and sabouraud agar supplemented with chloramphenicol, respectively. RESULTS: Down syndrome children had a higher caries-free rate (p |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/45863 10.6061/clinics/2012(09)04 |
url |
https://www.revistas.usp.br/clinics/article/view/45863 |
identifier_str_mv |
10.6061/clinics/2012(09)04 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/45863/49466 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 67 No. 9 (2012); 1007-1011 Clinics; v. 67 n. 9 (2012); 1007-1011 Clinics; Vol. 67 Núm. 9 (2012); 1007-1011 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222759121321984 |