Serum albumin level as a risk factor for mortality in burn patients
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/76922 |
Resumo: | OBJECTIVE: Hypoalbuminemia is a common clinical deficiency in burn patients and is associated with complications related to increased extravascular fluid, including edema, abnormal healing, and susceptibility to sepsis. Some prognostic scales do not include biochemical parameters, whereas others consider them together with comorbidities. The purpose of this study was to determine whether serum albumin can predict mortality in burn patients. METHODS: We studied burn patients ≥16 years of age who had complete clinical documentation, including the Abbreviated Burn Severity Index, serum albumin, globulin, and lipids. Sensitivity and specificity analyses were performed to determine the cut-off level of albumin that predicts mortality. RESULTS: In our analysis of 486 patients, we found that mortality was higher for burns caused by flame (p = 0.000), full-thickness burns (p = 0.004), inhalation injuries (p = 0.000), burns affecting >;30% of the body surface area (p = 0.001), and burns associated with infection (p = 0.008). Protein and lipid levels were lower in the patients who died (p |
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Clinics |
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Serum albumin level as a risk factor for mortality in burn patientsOBJECTIVE: Hypoalbuminemia is a common clinical deficiency in burn patients and is associated with complications related to increased extravascular fluid, including edema, abnormal healing, and susceptibility to sepsis. Some prognostic scales do not include biochemical parameters, whereas others consider them together with comorbidities. The purpose of this study was to determine whether serum albumin can predict mortality in burn patients. METHODS: We studied burn patients ≥16 years of age who had complete clinical documentation, including the Abbreviated Burn Severity Index, serum albumin, globulin, and lipids. Sensitivity and specificity analyses were performed to determine the cut-off level of albumin that predicts mortality. RESULTS: In our analysis of 486 patients, we found that mortality was higher for burns caused by flame (p = 0.000), full-thickness burns (p = 0.004), inhalation injuries (p = 0.000), burns affecting >;30% of the body surface area (p = 0.001), and burns associated with infection (p = 0.008). Protein and lipid levels were lower in the patients who died (pHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2013-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/7692210.1590/clin.v68i7.76922Clinics; Vol. 68 No. 7 (2013); 940-945Clinics; v. 68 n. 7 (2013); 940-945Clinics; Vol. 68 Núm. 7 (2013); 940-9451980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/76922/80783Alejandra Aguayo-Becerra, OliviaTorres-Garibay, CarlosDassaejv Macias-Amezcua, MichelFuentes-Orozco, Clotildede Guadalupe Chavez-Tostado, MarianaAndalon-Duenas, ElizabethEspinosa Partida, ArturoAlvarez-Villasenor, Andrea Del SocorroCortes-Flores, Ana OliviaAlejandro Gonzalez-Ojeda, Ana Oliviainfo:eu-repo/semantics/openAccess2014-03-24T11:50:37Zoai:revistas.usp.br:article/76922Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2014-03-24T11:50:37Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Serum albumin level as a risk factor for mortality in burn patients |
title |
Serum albumin level as a risk factor for mortality in burn patients |
spellingShingle |
Serum albumin level as a risk factor for mortality in burn patients Alejandra Aguayo-Becerra, Olivia |
title_short |
Serum albumin level as a risk factor for mortality in burn patients |
title_full |
Serum albumin level as a risk factor for mortality in burn patients |
title_fullStr |
Serum albumin level as a risk factor for mortality in burn patients |
title_full_unstemmed |
Serum albumin level as a risk factor for mortality in burn patients |
title_sort |
Serum albumin level as a risk factor for mortality in burn patients |
author |
Alejandra Aguayo-Becerra, Olivia |
author_facet |
Alejandra Aguayo-Becerra, Olivia Torres-Garibay, Carlos Dassaejv Macias-Amezcua, Michel Fuentes-Orozco, Clotilde de Guadalupe Chavez-Tostado, Mariana Andalon-Duenas, Elizabeth Espinosa Partida, Arturo Alvarez-Villasenor, Andrea Del Socorro Cortes-Flores, Ana Olivia Alejandro Gonzalez-Ojeda, Ana Olivia |
author_role |
author |
author2 |
Torres-Garibay, Carlos Dassaejv Macias-Amezcua, Michel Fuentes-Orozco, Clotilde de Guadalupe Chavez-Tostado, Mariana Andalon-Duenas, Elizabeth Espinosa Partida, Arturo Alvarez-Villasenor, Andrea Del Socorro Cortes-Flores, Ana Olivia Alejandro Gonzalez-Ojeda, Ana Olivia |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Alejandra Aguayo-Becerra, Olivia Torres-Garibay, Carlos Dassaejv Macias-Amezcua, Michel Fuentes-Orozco, Clotilde de Guadalupe Chavez-Tostado, Mariana Andalon-Duenas, Elizabeth Espinosa Partida, Arturo Alvarez-Villasenor, Andrea Del Socorro Cortes-Flores, Ana Olivia Alejandro Gonzalez-Ojeda, Ana Olivia |
description |
OBJECTIVE: Hypoalbuminemia is a common clinical deficiency in burn patients and is associated with complications related to increased extravascular fluid, including edema, abnormal healing, and susceptibility to sepsis. Some prognostic scales do not include biochemical parameters, whereas others consider them together with comorbidities. The purpose of this study was to determine whether serum albumin can predict mortality in burn patients. METHODS: We studied burn patients ≥16 years of age who had complete clinical documentation, including the Abbreviated Burn Severity Index, serum albumin, globulin, and lipids. Sensitivity and specificity analyses were performed to determine the cut-off level of albumin that predicts mortality. RESULTS: In our analysis of 486 patients, we found that mortality was higher for burns caused by flame (p = 0.000), full-thickness burns (p = 0.004), inhalation injuries (p = 0.000), burns affecting >;30% of the body surface area (p = 0.001), and burns associated with infection (p = 0.008). Protein and lipid levels were lower in the patients who died (p |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/76922 10.1590/clin.v68i7.76922 |
url |
https://www.revistas.usp.br/clinics/article/view/76922 |
identifier_str_mv |
10.1590/clin.v68i7.76922 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/76922/80783 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 68 No. 7 (2013); 940-945 Clinics; v. 68 n. 7 (2013); 940-945 Clinics; Vol. 68 Núm. 7 (2013); 940-945 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222760252735488 |