Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trial
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/77091 |
Resumo: | OBJECTIVE: This study compares the clinical, ultrasonography, radiography, and laboratory outcomes of painless and painful chronic synovitis in patients with established rheumatoid arthritis. METHODS: This cross-sectional study involved 60 patients with rheumatoid arthritis and synovitis in the metacarpophalangeal joints; 30 of the patients did not experience pain, and 30 had experienced pain for at least 6 months prior to the study. The radiocarpal, distal radioulnar, and metacarpophalangeal joints were evaluated using the ultrasound gray scale, power Doppler, and radiography. Past and present clinical and laboratory findings were also evaluated. RESULTS: There were no statistically significant differences between the groups for most of the outcomes. The group with pain scored worse on the disease activity indices (e.g., DAS 28 and SDAI), function questionnaires (HAQ and Cochin), and pinch strength test. A logistic regression analysis revealed that the use of an immunobiological agent was associated with a 3-fold greater chance of belonging to the group that experienced pain. The painless group had worse erosion scores in the second and fifth metacarpophalangeal with odd ratios (ORs) of 6.5 and 3.5, respectively. The painless group had more cartilage with grade 4 damage in the third metacarpophalangeal. CONCLUSIONS: The rheumatoid arthritis patients with both painless and painful synovitis exhibited similar disease histories and radiographic and ultrasound findings. However, the ultrasonography evaluation revealed worse scores in the second and fifth metacarpophalangeal of the synovitis patients who did not experience pain. |
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Clinics |
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Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trialOBJECTIVE: This study compares the clinical, ultrasonography, radiography, and laboratory outcomes of painless and painful chronic synovitis in patients with established rheumatoid arthritis. METHODS: This cross-sectional study involved 60 patients with rheumatoid arthritis and synovitis in the metacarpophalangeal joints; 30 of the patients did not experience pain, and 30 had experienced pain for at least 6 months prior to the study. The radiocarpal, distal radioulnar, and metacarpophalangeal joints were evaluated using the ultrasound gray scale, power Doppler, and radiography. Past and present clinical and laboratory findings were also evaluated. RESULTS: There were no statistically significant differences between the groups for most of the outcomes. The group with pain scored worse on the disease activity indices (e.g., DAS 28 and SDAI), function questionnaires (HAQ and Cochin), and pinch strength test. A logistic regression analysis revealed that the use of an immunobiological agent was associated with a 3-fold greater chance of belonging to the group that experienced pain. The painless group had worse erosion scores in the second and fifth metacarpophalangeal with odd ratios (ORs) of 6.5 and 3.5, respectively. The painless group had more cartilage with grade 4 damage in the third metacarpophalangeal. CONCLUSIONS: The rheumatoid arthritis patients with both painless and painful synovitis exhibited similar disease histories and radiographic and ultrasound findings. However, the ultrasonography evaluation revealed worse scores in the second and fifth metacarpophalangeal of the synovitis patients who did not experience pain.Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2014-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/7709110.1590/clin.v69i2.77091Clinics; Vol. 69 No. 2 (2014); 93-100Clinics; v. 69 n. 2 (2014); 93-100Clinics; Vol. 69 Núm. 2 (2014); 93-1001980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/77091/80958Pereira, Daniele FreitasNatour, JamilBuosi, Ana Leticia Pirozzi deFerreira, Fernando Bernardes Maia DinizFernandes, Artur da Rocha CorreaFurtado, Rita Nely Vilarinfo:eu-repo/semantics/openAccess2014-03-24T12:27:21Zoai:revistas.usp.br:article/77091Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2014-03-24T12:27:21Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trial |
title |
Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trial |
spellingShingle |
Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trial Pereira, Daniele Freitas |
title_short |
Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trial |
title_full |
Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trial |
title_fullStr |
Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trial |
title_full_unstemmed |
Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trial |
title_sort |
Is painless synovitis different from painful synovitis? A controlled, ultrasound, radiographic, clinical trial |
author |
Pereira, Daniele Freitas |
author_facet |
Pereira, Daniele Freitas Natour, Jamil Buosi, Ana Leticia Pirozzi de Ferreira, Fernando Bernardes Maia Diniz Fernandes, Artur da Rocha Correa Furtado, Rita Nely Vilar |
author_role |
author |
author2 |
Natour, Jamil Buosi, Ana Leticia Pirozzi de Ferreira, Fernando Bernardes Maia Diniz Fernandes, Artur da Rocha Correa Furtado, Rita Nely Vilar |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Pereira, Daniele Freitas Natour, Jamil Buosi, Ana Leticia Pirozzi de Ferreira, Fernando Bernardes Maia Diniz Fernandes, Artur da Rocha Correa Furtado, Rita Nely Vilar |
description |
OBJECTIVE: This study compares the clinical, ultrasonography, radiography, and laboratory outcomes of painless and painful chronic synovitis in patients with established rheumatoid arthritis. METHODS: This cross-sectional study involved 60 patients with rheumatoid arthritis and synovitis in the metacarpophalangeal joints; 30 of the patients did not experience pain, and 30 had experienced pain for at least 6 months prior to the study. The radiocarpal, distal radioulnar, and metacarpophalangeal joints were evaluated using the ultrasound gray scale, power Doppler, and radiography. Past and present clinical and laboratory findings were also evaluated. RESULTS: There were no statistically significant differences between the groups for most of the outcomes. The group with pain scored worse on the disease activity indices (e.g., DAS 28 and SDAI), function questionnaires (HAQ and Cochin), and pinch strength test. A logistic regression analysis revealed that the use of an immunobiological agent was associated with a 3-fold greater chance of belonging to the group that experienced pain. The painless group had worse erosion scores in the second and fifth metacarpophalangeal with odd ratios (ORs) of 6.5 and 3.5, respectively. The painless group had more cartilage with grade 4 damage in the third metacarpophalangeal. CONCLUSIONS: The rheumatoid arthritis patients with both painless and painful synovitis exhibited similar disease histories and radiographic and ultrasound findings. However, the ultrasonography evaluation revealed worse scores in the second and fifth metacarpophalangeal of the synovitis patients who did not experience pain. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/77091 10.1590/clin.v69i2.77091 |
url |
https://www.revistas.usp.br/clinics/article/view/77091 |
identifier_str_mv |
10.1590/clin.v69i2.77091 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/77091/80958 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 69 No. 2 (2014); 93-100 Clinics; v. 69 n. 2 (2014); 93-100 Clinics; Vol. 69 Núm. 2 (2014); 93-100 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222761114664960 |