An assessment of the use of the contraceptive Norplant in Rio de Janeiro, Brazil

Detalhes bibliográficos
Autor(a) principal: Koifman, Sérgio
Data de Publicação: 1987
Outros Autores: Paes, Sezisnando José Primo, Oliveira, Denize Paula, Vianna, Nilzete Ferreira, Giovanini, Maria Edea, Castro, Maria Luiza Oliveira de, Mota, Laine Galvão, Poyares, Jovina Amália Moraes, Gomes, Fátima Meireles Pereira, Castro, Ana Maria Monteiro de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/23461
Resumo: Anticonceptional methods for long-term have been searched for in many places. Norplant is one such, based on the use levonorgestrel capsules which introduced into women's arms, produce a daily secretion of hormones and have from two to five years' effect. It is produced under license from the Population Council and industrialised by Leiras Pharmaceutical. It has been used in Thailand, Egypt, Indonesia, Sweden, Denmark and Brazil. It is assessed the results of this method in Rio de Janeiro, where 175 Norplant users were interviewed at home, and their answers compared with those of two control groups (levonorgestrel pill-users and no-hormonal methods-users). The results show increased relative risks in Norplant users in menstrual disorders, hypertension, severe weight disturbances and hypertrichoses, all of them of statistical significance. Other non-statistical findings were angina pectoris, hypertensive encephalopaty, acne and duodenites. Some severe symptoms like headaches and behavioural disturbances were mentioned and these disappeared after the capsules had been withdrawn. It is discussed the relevance of all the side-effects in women who decided to interrupt the use of Norplant. In these cases follow-up measures are needed, in view of the fact that hemorrhage, marked weight gain and difficulties in pregnancy may developed.
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spelling An assessment of the use of the contraceptive Norplant in Rio de Janeiro, Brazil Avaliação do anticoncepcional Norplant no Município do Rio de Janeiro, RJ (Brasil) Anticoncepcionais femininos^i1^sefeitos adverAnticoncepção^i1^smétoEstudos de avaliaçãoRiscoContraceptive agentsfemale^i2^sadverse effeContraception^i2^smethEvaluation studiesRisk Anticonceptional methods for long-term have been searched for in many places. Norplant is one such, based on the use levonorgestrel capsules which introduced into women's arms, produce a daily secretion of hormones and have from two to five years' effect. It is produced under license from the Population Council and industrialised by Leiras Pharmaceutical. It has been used in Thailand, Egypt, Indonesia, Sweden, Denmark and Brazil. It is assessed the results of this method in Rio de Janeiro, where 175 Norplant users were interviewed at home, and their answers compared with those of two control groups (levonorgestrel pill-users and no-hormonal methods-users). The results show increased relative risks in Norplant users in menstrual disorders, hypertension, severe weight disturbances and hypertrichoses, all of them of statistical significance. Other non-statistical findings were angina pectoris, hypertensive encephalopaty, acne and duodenites. Some severe symptoms like headaches and behavioural disturbances were mentioned and these disappeared after the capsules had been withdrawn. It is discussed the relevance of all the side-effects in women who decided to interrupt the use of Norplant. In these cases follow-up measures are needed, in view of the fact that hemorrhage, marked weight gain and difficulties in pregnancy may developed. Métodos anticoncepcionais para longo tempo de uso têm sido buscados em vários lugares. O método Norplant é um deles, baseado em cápsulas de levonorgestrel introduzidas no braço das mulheres, através da liberação hormonal diária com efeito de dois a cinco anos. Norplant é produzido sob licença do "Population Council" e industrializado por "Leiras Pharmaceuticals", tendo sido usado na Tailândia, Egito, Indonésia, Suécia, Dinamarca e Brasil. Avaliam-se os resultados deste método, no Município do Rio de Janeiro (Brasil), onde 175 usuárias de Norplant foram entrevistadas em suas casas, e as respostas comparadas com dois grupos-controle (usuárias de pílulas à base de levonorgestrel e usuárias de métodos não-hormonais). Os resultados mostram aumento dos riscos relativos das usuárias de Norplant para desordens menstruais, hipertensão, graves distúrbios de peso e hipertricose, todos estes estatisticamente significantes. Outros achados não significantes foram angina pectoris, encefalopatia hipertensiva, acne e duodenite. Alguns sintomas graves como cefaléia e alterações de comportamento foram mencionados e desapareceram após a retirada das cápsulas. É discutida a relevância de todos os efeitos colaterais em mulheres que decidiram interromper o uso do Norplant. Nestes casos, as medidas de acompanhamento são necessárias, uma vez que hemorragia, ganho de peso acentuado e dificuldades na gravidez podem se desenvolver. Universidade de São Paulo. Faculdade de Saúde Pública1987-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/2346110.1590/S0034-89101987000600008Revista de Saúde Pública; Vol. 21 No. 6 (1987); 513-522 Revista de Saúde Pública; Vol. 21 Núm. 6 (1987); 513-522 Revista de Saúde Pública; v. 21 n. 6 (1987); 513-522 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/23461/25498Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessKoifman, SérgioPaes, Sezisnando José PrimoOliveira, Denize PaulaVianna, Nilzete FerreiraGiovanini, Maria EdeaCastro, Maria Luiza Oliveira deMota, Laine GalvãoPoyares, Jovina Amália MoraesGomes, Fátima Meireles PereiraCastro, Ana Maria Monteiro de2012-05-28T16:33:10Zoai:revistas.usp.br:article/23461Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-05-28T16:33:10Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv An assessment of the use of the contraceptive Norplant in Rio de Janeiro, Brazil
Avaliação do anticoncepcional Norplant no Município do Rio de Janeiro, RJ (Brasil)
title An assessment of the use of the contraceptive Norplant in Rio de Janeiro, Brazil
spellingShingle An assessment of the use of the contraceptive Norplant in Rio de Janeiro, Brazil
Koifman, Sérgio
Anticoncepcionais femininos^i1^sefeitos adver
Anticoncepção^i1^sméto
Estudos de avaliação
Risco
Contraceptive agents
female^i2^sadverse effe
Contraception^i2^smeth
Evaluation studies
Risk
title_short An assessment of the use of the contraceptive Norplant in Rio de Janeiro, Brazil
title_full An assessment of the use of the contraceptive Norplant in Rio de Janeiro, Brazil
title_fullStr An assessment of the use of the contraceptive Norplant in Rio de Janeiro, Brazil
title_full_unstemmed An assessment of the use of the contraceptive Norplant in Rio de Janeiro, Brazil
title_sort An assessment of the use of the contraceptive Norplant in Rio de Janeiro, Brazil
author Koifman, Sérgio
author_facet Koifman, Sérgio
Paes, Sezisnando José Primo
Oliveira, Denize Paula
Vianna, Nilzete Ferreira
Giovanini, Maria Edea
Castro, Maria Luiza Oliveira de
Mota, Laine Galvão
Poyares, Jovina Amália Moraes
Gomes, Fátima Meireles Pereira
Castro, Ana Maria Monteiro de
author_role author
author2 Paes, Sezisnando José Primo
Oliveira, Denize Paula
Vianna, Nilzete Ferreira
Giovanini, Maria Edea
Castro, Maria Luiza Oliveira de
Mota, Laine Galvão
Poyares, Jovina Amália Moraes
Gomes, Fátima Meireles Pereira
Castro, Ana Maria Monteiro de
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Koifman, Sérgio
Paes, Sezisnando José Primo
Oliveira, Denize Paula
Vianna, Nilzete Ferreira
Giovanini, Maria Edea
Castro, Maria Luiza Oliveira de
Mota, Laine Galvão
Poyares, Jovina Amália Moraes
Gomes, Fátima Meireles Pereira
Castro, Ana Maria Monteiro de
dc.subject.por.fl_str_mv Anticoncepcionais femininos^i1^sefeitos adver
Anticoncepção^i1^sméto
Estudos de avaliação
Risco
Contraceptive agents
female^i2^sadverse effe
Contraception^i2^smeth
Evaluation studies
Risk
topic Anticoncepcionais femininos^i1^sefeitos adver
Anticoncepção^i1^sméto
Estudos de avaliação
Risco
Contraceptive agents
female^i2^sadverse effe
Contraception^i2^smeth
Evaluation studies
Risk
description Anticonceptional methods for long-term have been searched for in many places. Norplant is one such, based on the use levonorgestrel capsules which introduced into women's arms, produce a daily secretion of hormones and have from two to five years' effect. It is produced under license from the Population Council and industrialised by Leiras Pharmaceutical. It has been used in Thailand, Egypt, Indonesia, Sweden, Denmark and Brazil. It is assessed the results of this method in Rio de Janeiro, where 175 Norplant users were interviewed at home, and their answers compared with those of two control groups (levonorgestrel pill-users and no-hormonal methods-users). The results show increased relative risks in Norplant users in menstrual disorders, hypertension, severe weight disturbances and hypertrichoses, all of them of statistical significance. Other non-statistical findings were angina pectoris, hypertensive encephalopaty, acne and duodenites. Some severe symptoms like headaches and behavioural disturbances were mentioned and these disappeared after the capsules had been withdrawn. It is discussed the relevance of all the side-effects in women who decided to interrupt the use of Norplant. In these cases follow-up measures are needed, in view of the fact that hemorrhage, marked weight gain and difficulties in pregnancy may developed.
publishDate 1987
dc.date.none.fl_str_mv 1987-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/23461
10.1590/S0034-89101987000600008
url https://www.revistas.usp.br/rsp/article/view/23461
identifier_str_mv 10.1590/S0034-89101987000600008
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/23461/25498
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 21 No. 6 (1987); 513-522
Revista de Saúde Pública; Vol. 21 Núm. 6 (1987); 513-522
Revista de Saúde Pública; v. 21 n. 6 (1987); 513-522
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
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instname_str Universidade de São Paulo (USP)
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institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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