An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil)

Detalhes bibliográficos
Autor(a) principal: Mendes, Inácio França
Data de Publicação: 1985
Outros Autores: Pral, Michel Marie, Miyaki, Cosue, Gallina, Neuza Maria Frazatti, Petricevich, Vera Lucia, Fang, Francisco Liauw Woe, Tuchiya, Hiroko Nakahata, Ninomya, Tuyoshi, Rizzo, Edda de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/23315
Resumo: In the State of S. Paulo, Brazil, health centers sponsored by the State, as well as private health services, located in throughout large districts, are in charge of the vaccination against the various diseases affecting children, including measles. In the present study three of the above mentioned districts, covering 385 State Health Centers (SHC) and 200 Private Health Services (PHS) were surveyed. From these totals 117 SHC and 71 PHS were chosen for the evaluation of: a) quality of the existing cold chain for measles vaccine storage (temperatura); b) vaccine titer; c) validity; d) protection from light. Of the SHC inspected, 85.33% kept vaccines at the recommended temperature, 100% presented vaccines with titers above the minimum required and within expiration date. Deficiency relating to protection from light, was found in 83.06%. Inspection of the PHS revealed that whereas 66.20% kept vaccine within the right temperature range, 76.06% did not protect them against light, only 96.47% had vaccines with potency above the level required and only 85.51%, observed the expiration date. The study led to the conclusion that in the State of S. Paulo, measles vaccines are better stored in the State Health Centers than in the Private Health Services surveyed indicating that the slight preference that parents show towards having their children vaccinated in PHS is not justified. It was suggested that some conditions of measles vaccine storage montly, temperature and protection from light should be improved and that instruction leaflets must always accompany immunobiological materials distributed to all health centers, to be consulted when doubts about the proper storage and administration of these vaccines arise.
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spelling An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil) Avaliação das condições de estocagem de vacinas vivas, atenuadas contra o sarampo, em postos de vacinação credenciados e em centros de saúde do Estado de São Paulo (Brasil) Sarampo^i1^svacPostos de Vacinação CredenciadosCentros de SaúdeControle de qualidadeAvaliaçãoestudosMeasles^i2^svaccCommunity Health ServicesPrivate Health ServicesQuality controlEvaluating studies In the State of S. Paulo, Brazil, health centers sponsored by the State, as well as private health services, located in throughout large districts, are in charge of the vaccination against the various diseases affecting children, including measles. In the present study three of the above mentioned districts, covering 385 State Health Centers (SHC) and 200 Private Health Services (PHS) were surveyed. From these totals 117 SHC and 71 PHS were chosen for the evaluation of: a) quality of the existing cold chain for measles vaccine storage (temperatura); b) vaccine titer; c) validity; d) protection from light. Of the SHC inspected, 85.33% kept vaccines at the recommended temperature, 100% presented vaccines with titers above the minimum required and within expiration date. Deficiency relating to protection from light, was found in 83.06%. Inspection of the PHS revealed that whereas 66.20% kept vaccine within the right temperature range, 76.06% did not protect them against light, only 96.47% had vaccines with potency above the level required and only 85.51%, observed the expiration date. The study led to the conclusion that in the State of S. Paulo, measles vaccines are better stored in the State Health Centers than in the Private Health Services surveyed indicating that the slight preference that parents show towards having their children vaccinated in PHS is not justified. It was suggested that some conditions of measles vaccine storage montly, temperature and protection from light should be improved and that instruction leaflets must always accompany immunobiological materials distributed to all health centers, to be consulted when doubts about the proper storage and administration of these vaccines arise. Para avaliar as condições de estocagem de vacinas vivas, atenuadas contra o sarampo, da rede de vacinação do Estado de São Paulo (Brasil), foram visitados 71 Postos de Vacinação Credenciados particulares (PVC), assim como 117 Centros de Saúde oficiais (CS), sobre os quais interessava saber a respeito da qualidade da estocagem a frio. Os parâmetros adotados foram: a) temperatura das geladeiras de uso (+2 a +8°C) e de estoque (+ 8°C); b) validade do produto; c) título das vacinas conservadas nestas geladeiras, avaliado pela inoculação de diluições das amostras de vacinas em células Vero; d) proteção à luz. Dos CS pesquisados, 85,33% apresentaram geladeiras com temperatura de acordo com a recomendada e 100% das vacinas neles estocadas com título e validade satisfatórios. Nos PVC foram encontrados, com maior freqüência, lotes de vacina fora do prazo de validade (14,49%), com títulos abaixo do mínimo requerido (3,53%) e geladeiras de uso e de estoque com temperaturas inadequadas (33,80%). Necessário se faz que as condições de estocagem das vacinas contra o sarampo (temperatura e proteção à luz), prevalentes no momento, sejam melhoradas e que as bulas passem a acompanhar o produto a eles entregue, para que os responsáveis pela vacinação obedeçam as recomendações do laboratório produtor com relação às condições de estocagem, validade e administração do imunobiológico, uma vez que a pesquisa revelou que estas não são observadas com o rigor necessário. Universidade de São Paulo. Faculdade de Saúde Pública1985-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/2331510.1590/S0034-89101985000500008Revista de Saúde Pública; Vol. 19 No. 5 (1985); 444-449 Revista de Saúde Pública; Vol. 19 Núm. 5 (1985); 444-449 Revista de Saúde Pública; v. 19 n. 5 (1985); 444-449 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/23315/25344Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessMendes, Inácio FrançaPral, Michel MarieMiyaki, CosueGallina, Neuza Maria FrazattiPetricevich, Vera LuciaFang, Francisco Liauw WoeTuchiya, Hiroko NakahataNinomya, TuyoshiRizzo, Edda de2012-05-28T16:12:20Zoai:revistas.usp.br:article/23315Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-05-28T16:12:20Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil)
Avaliação das condições de estocagem de vacinas vivas, atenuadas contra o sarampo, em postos de vacinação credenciados e em centros de saúde do Estado de São Paulo (Brasil)
title An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil)
spellingShingle An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil)
Mendes, Inácio França
Sarampo^i1^svac
Postos de Vacinação Credenciados
Centros de Saúde
Controle de qualidade
Avaliação
estudos
Measles^i2^svacc
Community Health Services
Private Health Services
Quality control
Evaluating studies
title_short An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil)
title_full An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil)
title_fullStr An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil)
title_full_unstemmed An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil)
title_sort An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil)
author Mendes, Inácio França
author_facet Mendes, Inácio França
Pral, Michel Marie
Miyaki, Cosue
Gallina, Neuza Maria Frazatti
Petricevich, Vera Lucia
Fang, Francisco Liauw Woe
Tuchiya, Hiroko Nakahata
Ninomya, Tuyoshi
Rizzo, Edda de
author_role author
author2 Pral, Michel Marie
Miyaki, Cosue
Gallina, Neuza Maria Frazatti
Petricevich, Vera Lucia
Fang, Francisco Liauw Woe
Tuchiya, Hiroko Nakahata
Ninomya, Tuyoshi
Rizzo, Edda de
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mendes, Inácio França
Pral, Michel Marie
Miyaki, Cosue
Gallina, Neuza Maria Frazatti
Petricevich, Vera Lucia
Fang, Francisco Liauw Woe
Tuchiya, Hiroko Nakahata
Ninomya, Tuyoshi
Rizzo, Edda de
dc.subject.por.fl_str_mv Sarampo^i1^svac
Postos de Vacinação Credenciados
Centros de Saúde
Controle de qualidade
Avaliação
estudos
Measles^i2^svacc
Community Health Services
Private Health Services
Quality control
Evaluating studies
topic Sarampo^i1^svac
Postos de Vacinação Credenciados
Centros de Saúde
Controle de qualidade
Avaliação
estudos
Measles^i2^svacc
Community Health Services
Private Health Services
Quality control
Evaluating studies
description In the State of S. Paulo, Brazil, health centers sponsored by the State, as well as private health services, located in throughout large districts, are in charge of the vaccination against the various diseases affecting children, including measles. In the present study three of the above mentioned districts, covering 385 State Health Centers (SHC) and 200 Private Health Services (PHS) were surveyed. From these totals 117 SHC and 71 PHS were chosen for the evaluation of: a) quality of the existing cold chain for measles vaccine storage (temperatura); b) vaccine titer; c) validity; d) protection from light. Of the SHC inspected, 85.33% kept vaccines at the recommended temperature, 100% presented vaccines with titers above the minimum required and within expiration date. Deficiency relating to protection from light, was found in 83.06%. Inspection of the PHS revealed that whereas 66.20% kept vaccine within the right temperature range, 76.06% did not protect them against light, only 96.47% had vaccines with potency above the level required and only 85.51%, observed the expiration date. The study led to the conclusion that in the State of S. Paulo, measles vaccines are better stored in the State Health Centers than in the Private Health Services surveyed indicating that the slight preference that parents show towards having their children vaccinated in PHS is not justified. It was suggested that some conditions of measles vaccine storage montly, temperature and protection from light should be improved and that instruction leaflets must always accompany immunobiological materials distributed to all health centers, to be consulted when doubts about the proper storage and administration of these vaccines arise.
publishDate 1985
dc.date.none.fl_str_mv 1985-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/23315
10.1590/S0034-89101985000500008
url https://www.revistas.usp.br/rsp/article/view/23315
identifier_str_mv 10.1590/S0034-89101985000500008
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/23315/25344
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 19 No. 5 (1985); 444-449
Revista de Saúde Pública; Vol. 19 Núm. 5 (1985); 444-449
Revista de Saúde Pública; v. 19 n. 5 (1985); 444-449
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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