An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil)
Autor(a) principal: | |
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Data de Publicação: | 1985 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista de Saúde Pública |
Texto Completo: | https://www.revistas.usp.br/rsp/article/view/23315 |
Resumo: | In the State of S. Paulo, Brazil, health centers sponsored by the State, as well as private health services, located in throughout large districts, are in charge of the vaccination against the various diseases affecting children, including measles. In the present study three of the above mentioned districts, covering 385 State Health Centers (SHC) and 200 Private Health Services (PHS) were surveyed. From these totals 117 SHC and 71 PHS were chosen for the evaluation of: a) quality of the existing cold chain for measles vaccine storage (temperatura); b) vaccine titer; c) validity; d) protection from light. Of the SHC inspected, 85.33% kept vaccines at the recommended temperature, 100% presented vaccines with titers above the minimum required and within expiration date. Deficiency relating to protection from light, was found in 83.06%. Inspection of the PHS revealed that whereas 66.20% kept vaccine within the right temperature range, 76.06% did not protect them against light, only 96.47% had vaccines with potency above the level required and only 85.51%, observed the expiration date. The study led to the conclusion that in the State of S. Paulo, measles vaccines are better stored in the State Health Centers than in the Private Health Services surveyed indicating that the slight preference that parents show towards having their children vaccinated in PHS is not justified. It was suggested that some conditions of measles vaccine storage montly, temperature and protection from light should be improved and that instruction leaflets must always accompany immunobiological materials distributed to all health centers, to be consulted when doubts about the proper storage and administration of these vaccines arise. |
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An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil) Avaliação das condições de estocagem de vacinas vivas, atenuadas contra o sarampo, em postos de vacinação credenciados e em centros de saúde do Estado de São Paulo (Brasil) Sarampo^i1^svacPostos de Vacinação CredenciadosCentros de SaúdeControle de qualidadeAvaliaçãoestudosMeasles^i2^svaccCommunity Health ServicesPrivate Health ServicesQuality controlEvaluating studies In the State of S. Paulo, Brazil, health centers sponsored by the State, as well as private health services, located in throughout large districts, are in charge of the vaccination against the various diseases affecting children, including measles. In the present study three of the above mentioned districts, covering 385 State Health Centers (SHC) and 200 Private Health Services (PHS) were surveyed. From these totals 117 SHC and 71 PHS were chosen for the evaluation of: a) quality of the existing cold chain for measles vaccine storage (temperatura); b) vaccine titer; c) validity; d) protection from light. Of the SHC inspected, 85.33% kept vaccines at the recommended temperature, 100% presented vaccines with titers above the minimum required and within expiration date. Deficiency relating to protection from light, was found in 83.06%. Inspection of the PHS revealed that whereas 66.20% kept vaccine within the right temperature range, 76.06% did not protect them against light, only 96.47% had vaccines with potency above the level required and only 85.51%, observed the expiration date. The study led to the conclusion that in the State of S. Paulo, measles vaccines are better stored in the State Health Centers than in the Private Health Services surveyed indicating that the slight preference that parents show towards having their children vaccinated in PHS is not justified. It was suggested that some conditions of measles vaccine storage montly, temperature and protection from light should be improved and that instruction leaflets must always accompany immunobiological materials distributed to all health centers, to be consulted when doubts about the proper storage and administration of these vaccines arise. Para avaliar as condições de estocagem de vacinas vivas, atenuadas contra o sarampo, da rede de vacinação do Estado de São Paulo (Brasil), foram visitados 71 Postos de Vacinação Credenciados particulares (PVC), assim como 117 Centros de Saúde oficiais (CS), sobre os quais interessava saber a respeito da qualidade da estocagem a frio. Os parâmetros adotados foram: a) temperatura das geladeiras de uso (+2 a +8°C) e de estoque (+ 8°C); b) validade do produto; c) título das vacinas conservadas nestas geladeiras, avaliado pela inoculação de diluições das amostras de vacinas em células Vero; d) proteção à luz. Dos CS pesquisados, 85,33% apresentaram geladeiras com temperatura de acordo com a recomendada e 100% das vacinas neles estocadas com título e validade satisfatórios. Nos PVC foram encontrados, com maior freqüência, lotes de vacina fora do prazo de validade (14,49%), com títulos abaixo do mínimo requerido (3,53%) e geladeiras de uso e de estoque com temperaturas inadequadas (33,80%). Necessário se faz que as condições de estocagem das vacinas contra o sarampo (temperatura e proteção à luz), prevalentes no momento, sejam melhoradas e que as bulas passem a acompanhar o produto a eles entregue, para que os responsáveis pela vacinação obedeçam as recomendações do laboratório produtor com relação às condições de estocagem, validade e administração do imunobiológico, uma vez que a pesquisa revelou que estas não são observadas com o rigor necessário. Universidade de São Paulo. Faculdade de Saúde Pública1985-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/2331510.1590/S0034-89101985000500008Revista de Saúde Pública; Vol. 19 No. 5 (1985); 444-449 Revista de Saúde Pública; Vol. 19 Núm. 5 (1985); 444-449 Revista de Saúde Pública; v. 19 n. 5 (1985); 444-449 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/23315/25344Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessMendes, Inácio FrançaPral, Michel MarieMiyaki, CosueGallina, Neuza Maria FrazattiPetricevich, Vera LuciaFang, Francisco Liauw WoeTuchiya, Hiroko NakahataNinomya, TuyoshiRizzo, Edda de2012-05-28T16:12:20Zoai:revistas.usp.br:article/23315Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-05-28T16:12:20Revista de Saúde Pública - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil) Avaliação das condições de estocagem de vacinas vivas, atenuadas contra o sarampo, em postos de vacinação credenciados e em centros de saúde do Estado de São Paulo (Brasil) |
title |
An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil) |
spellingShingle |
An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil) Mendes, Inácio França Sarampo^i1^svac Postos de Vacinação Credenciados Centros de Saúde Controle de qualidade Avaliação estudos Measles^i2^svacc Community Health Services Private Health Services Quality control Evaluating studies |
title_short |
An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil) |
title_full |
An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil) |
title_fullStr |
An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil) |
title_full_unstemmed |
An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil) |
title_sort |
An assessment of the storage conditions of live, attenuated vaccines against measles, in authorized vaccination centers and in health services in S. Paulo State (Brazil) |
author |
Mendes, Inácio França |
author_facet |
Mendes, Inácio França Pral, Michel Marie Miyaki, Cosue Gallina, Neuza Maria Frazatti Petricevich, Vera Lucia Fang, Francisco Liauw Woe Tuchiya, Hiroko Nakahata Ninomya, Tuyoshi Rizzo, Edda de |
author_role |
author |
author2 |
Pral, Michel Marie Miyaki, Cosue Gallina, Neuza Maria Frazatti Petricevich, Vera Lucia Fang, Francisco Liauw Woe Tuchiya, Hiroko Nakahata Ninomya, Tuyoshi Rizzo, Edda de |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Mendes, Inácio França Pral, Michel Marie Miyaki, Cosue Gallina, Neuza Maria Frazatti Petricevich, Vera Lucia Fang, Francisco Liauw Woe Tuchiya, Hiroko Nakahata Ninomya, Tuyoshi Rizzo, Edda de |
dc.subject.por.fl_str_mv |
Sarampo^i1^svac Postos de Vacinação Credenciados Centros de Saúde Controle de qualidade Avaliação estudos Measles^i2^svacc Community Health Services Private Health Services Quality control Evaluating studies |
topic |
Sarampo^i1^svac Postos de Vacinação Credenciados Centros de Saúde Controle de qualidade Avaliação estudos Measles^i2^svacc Community Health Services Private Health Services Quality control Evaluating studies |
description |
In the State of S. Paulo, Brazil, health centers sponsored by the State, as well as private health services, located in throughout large districts, are in charge of the vaccination against the various diseases affecting children, including measles. In the present study three of the above mentioned districts, covering 385 State Health Centers (SHC) and 200 Private Health Services (PHS) were surveyed. From these totals 117 SHC and 71 PHS were chosen for the evaluation of: a) quality of the existing cold chain for measles vaccine storage (temperatura); b) vaccine titer; c) validity; d) protection from light. Of the SHC inspected, 85.33% kept vaccines at the recommended temperature, 100% presented vaccines with titers above the minimum required and within expiration date. Deficiency relating to protection from light, was found in 83.06%. Inspection of the PHS revealed that whereas 66.20% kept vaccine within the right temperature range, 76.06% did not protect them against light, only 96.47% had vaccines with potency above the level required and only 85.51%, observed the expiration date. The study led to the conclusion that in the State of S. Paulo, measles vaccines are better stored in the State Health Centers than in the Private Health Services surveyed indicating that the slight preference that parents show towards having their children vaccinated in PHS is not justified. It was suggested that some conditions of measles vaccine storage montly, temperature and protection from light should be improved and that instruction leaflets must always accompany immunobiological materials distributed to all health centers, to be consulted when doubts about the proper storage and administration of these vaccines arise. |
publishDate |
1985 |
dc.date.none.fl_str_mv |
1985-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rsp/article/view/23315 10.1590/S0034-89101985000500008 |
url |
https://www.revistas.usp.br/rsp/article/view/23315 |
identifier_str_mv |
10.1590/S0034-89101985000500008 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rsp/article/view/23315/25344 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Revista de Saúde Pública info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Revista de Saúde Pública |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Saúde Pública |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Saúde Pública |
dc.source.none.fl_str_mv |
Revista de Saúde Pública; Vol. 19 No. 5 (1985); 444-449 Revista de Saúde Pública; Vol. 19 Núm. 5 (1985); 444-449 Revista de Saúde Pública; v. 19 n. 5 (1985); 444-449 1518-8787 0034-8910 reponame:Revista de Saúde Pública instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Revista de Saúde Pública |
collection |
Revista de Saúde Pública |
repository.name.fl_str_mv |
Revista de Saúde Pública - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
revsp@org.usp.br||revsp1@usp.br |
_version_ |
1800221772554960896 |