Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102018000100255 |
Resumo: | ABSTRACT OBJECTIVE To present the development and validation of the WebAd-Q Questionnaire, a self-report instrument to monitor adherence to antiretroviral therapy in HIV/AIDS centers in Brazil. METHODS The WebAd-Q is an electronic questionnaire that has three questions about the use of antiretrovirals in the last week. It was constructed from interviews and focus groups with 38 patients. Its validity was tested in a study with a sample of 90 adult patients on antiretroviral therapy for at least three months. We used electronic monitoring bottles, pill counting, and self-report interview to compare adherence. The WebAd-Q was answered on the sixtieth day, twice, with at least one hour of interval. The viral load of the patients was obtained from the service records. We have analyzed the agreement between the answers to the WebAd-Q, the associations, and the correlations with viral load and performance compared to other measures of adherence. RESULTS Among the invited patients, 74 (82.2%) answered the WebAd-Q. No difficulties were reported to answer the questionnaire. The average answer time was 5 min 47 sec. The set of three questions of the WebAd-Q obtained agreement of 89.8%, with Kappa of 0.77 (95%CI 0.61–0.94). The non-adherence answers of the WebAd-Q were associated with detectable viral load. We obtained moderate viral load correlations with the non-adherence scale according to the WebAd-Q. For the three questions of the WebAd-Q, patients with non-adherence answers were also reported as less adherent according to the other measures of adherence. CONCLUSIONS The WebAd-Q answered all the issues considered relevant in the validation of questionnaires, was well understood by patients, was associated with viral load, and obtained good agreement and good performance compared to the other measures. The feasibility analysis of its implementation still depends on a national study on its applicability. |
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Revista de Saúde Pública |
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Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapyAnti-HIV Agents, supply & distributionHIV Infections, drug therapyMedication AdherenceSurveys and Questionnaires, utilizationValidation StudiesABSTRACT OBJECTIVE To present the development and validation of the WebAd-Q Questionnaire, a self-report instrument to monitor adherence to antiretroviral therapy in HIV/AIDS centers in Brazil. METHODS The WebAd-Q is an electronic questionnaire that has three questions about the use of antiretrovirals in the last week. It was constructed from interviews and focus groups with 38 patients. Its validity was tested in a study with a sample of 90 adult patients on antiretroviral therapy for at least three months. We used electronic monitoring bottles, pill counting, and self-report interview to compare adherence. The WebAd-Q was answered on the sixtieth day, twice, with at least one hour of interval. The viral load of the patients was obtained from the service records. We have analyzed the agreement between the answers to the WebAd-Q, the associations, and the correlations with viral load and performance compared to other measures of adherence. RESULTS Among the invited patients, 74 (82.2%) answered the WebAd-Q. No difficulties were reported to answer the questionnaire. The average answer time was 5 min 47 sec. The set of three questions of the WebAd-Q obtained agreement of 89.8%, with Kappa of 0.77 (95%CI 0.61–0.94). The non-adherence answers of the WebAd-Q were associated with detectable viral load. We obtained moderate viral load correlations with the non-adherence scale according to the WebAd-Q. For the three questions of the WebAd-Q, patients with non-adherence answers were also reported as less adherent according to the other measures of adherence. CONCLUSIONS The WebAd-Q answered all the issues considered relevant in the validation of questionnaires, was well understood by patients, was associated with viral load, and obtained good agreement and good performance compared to the other measures. The feasibility analysis of its implementation still depends on a national study on its applicability.Faculdade de Saúde Pública da Universidade de São Paulo2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102018000100255Revista de Saúde Pública v.52 2018reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USP10.11606/s1518-8787.2018052000337info:eu-repo/semantics/openAccessVale,Felipe CamposSanta-Helena,Ernani Tiaraju deSantos,Maria AltenfelderCarvalho,Wania Maria do Espirito SantoMenezes,Paulo RossiBasso,Caritas RelvaSilva,Mariliza HenriqueAlves,Ana MarosoNemes,Maria Ines Battistellaeng2018-05-24T00:00:00Zoai:scielo:S0034-89102018000100255Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0034-8910&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.phprevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2018-05-24T00:00Revista de Saúde Pública - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy |
title |
Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy |
spellingShingle |
Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy Vale,Felipe Campos Anti-HIV Agents, supply & distribution HIV Infections, drug therapy Medication Adherence Surveys and Questionnaires, utilization Validation Studies |
title_short |
Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy |
title_full |
Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy |
title_fullStr |
Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy |
title_full_unstemmed |
Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy |
title_sort |
Development and validation of the WebAd-Q Questionnaire to monitor adherence to HIV therapy |
author |
Vale,Felipe Campos |
author_facet |
Vale,Felipe Campos Santa-Helena,Ernani Tiaraju de Santos,Maria Altenfelder Carvalho,Wania Maria do Espirito Santo Menezes,Paulo Rossi Basso,Caritas Relva Silva,Mariliza Henrique Alves,Ana Maroso Nemes,Maria Ines Battistella |
author_role |
author |
author2 |
Santa-Helena,Ernani Tiaraju de Santos,Maria Altenfelder Carvalho,Wania Maria do Espirito Santo Menezes,Paulo Rossi Basso,Caritas Relva Silva,Mariliza Henrique Alves,Ana Maroso Nemes,Maria Ines Battistella |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Vale,Felipe Campos Santa-Helena,Ernani Tiaraju de Santos,Maria Altenfelder Carvalho,Wania Maria do Espirito Santo Menezes,Paulo Rossi Basso,Caritas Relva Silva,Mariliza Henrique Alves,Ana Maroso Nemes,Maria Ines Battistella |
dc.subject.por.fl_str_mv |
Anti-HIV Agents, supply & distribution HIV Infections, drug therapy Medication Adherence Surveys and Questionnaires, utilization Validation Studies |
topic |
Anti-HIV Agents, supply & distribution HIV Infections, drug therapy Medication Adherence Surveys and Questionnaires, utilization Validation Studies |
description |
ABSTRACT OBJECTIVE To present the development and validation of the WebAd-Q Questionnaire, a self-report instrument to monitor adherence to antiretroviral therapy in HIV/AIDS centers in Brazil. METHODS The WebAd-Q is an electronic questionnaire that has three questions about the use of antiretrovirals in the last week. It was constructed from interviews and focus groups with 38 patients. Its validity was tested in a study with a sample of 90 adult patients on antiretroviral therapy for at least three months. We used electronic monitoring bottles, pill counting, and self-report interview to compare adherence. The WebAd-Q was answered on the sixtieth day, twice, with at least one hour of interval. The viral load of the patients was obtained from the service records. We have analyzed the agreement between the answers to the WebAd-Q, the associations, and the correlations with viral load and performance compared to other measures of adherence. RESULTS Among the invited patients, 74 (82.2%) answered the WebAd-Q. No difficulties were reported to answer the questionnaire. The average answer time was 5 min 47 sec. The set of three questions of the WebAd-Q obtained agreement of 89.8%, with Kappa of 0.77 (95%CI 0.61–0.94). The non-adherence answers of the WebAd-Q were associated with detectable viral load. We obtained moderate viral load correlations with the non-adherence scale according to the WebAd-Q. For the three questions of the WebAd-Q, patients with non-adherence answers were also reported as less adherent according to the other measures of adherence. CONCLUSIONS The WebAd-Q answered all the issues considered relevant in the validation of questionnaires, was well understood by patients, was associated with viral load, and obtained good agreement and good performance compared to the other measures. The feasibility analysis of its implementation still depends on a national study on its applicability. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102018000100255 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102018000100255 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.11606/s1518-8787.2018052000337 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
dc.source.none.fl_str_mv |
Revista de Saúde Pública v.52 2018 reponame:Revista de Saúde Pública instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Revista de Saúde Pública |
collection |
Revista de Saúde Pública |
repository.name.fl_str_mv |
Revista de Saúde Pública - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
revsp@org.usp.br||revsp1@usp.br |
_version_ |
1748936504739102720 |