Comparison of the erythroimmunoadsorption by capture, immunoenzymatic and passive haemagglutination tests used in the diagnosis of neurocysticercosis

• Autor(a) principal: Pialarissi, C. S. M.
• Data de Publicação: 1995
• Outros Autores: Nitrini, S. M. O. O.
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista de Saúde Pública
• DOI: 10.1590/S0034-89101995000200005
• Texto Completo: https://www.revistas.usp.br/rsp/article/view/24095
• topic: Cisticercose^i1^sdiagnóst; Técnicas de imunoadsorção^i1^sutiliza; ELISA^i1^sutiliza; Testes de hemaglutinação^i1^sutiliza; Cysticercosis^i2^sdiagno; Immunosorbent techniques^i2^sutilizat; Enzyme-linked immunosorbent assay^i2^sutilizat; Hemmagglutination tests^i2^sutilizat

Comparisons were made among the erythroimmunoadsorption by capture (C-EIA), the immunoenzymatic (ELISA) and passive haemaglutination (P.H.A.) tests used in the diagnosis of neurocysticercosis. The three tests, two of them routine by in diagnosis, and the third one (C-EIA) recently, standardised were compared for the detection of anti-Cysticercus cellulosae antibodies. In the three reactions the antigen utilized was raw saline extract (R.S.E) with a yield of 0.1, 1 and 10 µg protein/cavity for the C-EIA, ELISA and P.H.A tests, respectively. In a group of 58 patients with neurocysticercosis, the sensitivity to the ELISA, C-EIA and P.H.A tests was of 98.2%, 84.5% and 77,2%, respectively. In the control group of 85 individuals, healthy or with encephalopathies other than neurocysticercosis, the sensitivity was of 98.27%, 84.48% and 79.63%, respectively, and the specificity was of 94.1%, 95.3% and 91.8%. This order of choice should be followed, depending on the resources available.