Diagnosis of iron deficiency anemia in children of Northeast Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2010 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102010000300015 |
Resumo: | OBJECTIVE: To diagnose iron deficiency anemia in children. METHODS: The study was conducted with a sample of 301 children aged six to 30 months attending public daycare centers in the city of Recife, Northeast Brazil, in 2004. The diagnoses of anemia were based on a combination of different hematological and biochemical parameters: hemoglobin, mean corpuscular volume, ferritin, C-reactive protein, transferrin saturation and transferrin receptor. The chi-square test and ANOVA were used in the statistical analysis. RESULTS: Of all children studied, 92.4% had anemia (Hb <110 g/L) and 28.9% had moderate/severe anemia (Hb <90 g/L). Lower levels of hemoglobin were found in children aged 6-17 months. Iron deficiency was found in 51.5% of children using ferritin (<12 μg/L) as parameter. Taking into consideration the combination of hemoglobin level, ferritin and transferrin receptor, 58.1% had anemia with iron deficiency, 34.2% had anemia without iron deficiency and 2.3% had iron deficiency without anemia. Mean ferritin concentration was significantly higher in children with high C-reactive protein when compared with those with normal levels (22.1 vs. 14.8 µg/L). CONCLUSIONS: The use of several biochemical and hematological parameters allowed to diagnosing iron deficiency anemia in two thirds of children, suggesting a need to identify other determinants of anemia without iron deficiency. |
id |
USP-23_9fb7de60864c7c73e4aacf383ff42791 |
---|---|
oai_identifier_str |
oai:scielo:S0034-89102010000300015 |
network_acronym_str |
USP-23 |
network_name_str |
Revista de Saúde Pública |
repository_id_str |
|
spelling |
Diagnosis of iron deficiency anemia in children of Northeast BrazilAnemia, Iron Deficiency/diagnosisFerritins/bloodLaboratory Techniques and ProceduresHematologic TestsIron Deficiency/preventionIron Deficiency/controlInfant NutritionChild NutritionOBJECTIVE: To diagnose iron deficiency anemia in children. METHODS: The study was conducted with a sample of 301 children aged six to 30 months attending public daycare centers in the city of Recife, Northeast Brazil, in 2004. The diagnoses of anemia were based on a combination of different hematological and biochemical parameters: hemoglobin, mean corpuscular volume, ferritin, C-reactive protein, transferrin saturation and transferrin receptor. The chi-square test and ANOVA were used in the statistical analysis. RESULTS: Of all children studied, 92.4% had anemia (Hb <110 g/L) and 28.9% had moderate/severe anemia (Hb <90 g/L). Lower levels of hemoglobin were found in children aged 6-17 months. Iron deficiency was found in 51.5% of children using ferritin (<12 μg/L) as parameter. Taking into consideration the combination of hemoglobin level, ferritin and transferrin receptor, 58.1% had anemia with iron deficiency, 34.2% had anemia without iron deficiency and 2.3% had iron deficiency without anemia. Mean ferritin concentration was significantly higher in children with high C-reactive protein when compared with those with normal levels (22.1 vs. 14.8 µg/L). CONCLUSIONS: The use of several biochemical and hematological parameters allowed to diagnosing iron deficiency anemia in two thirds of children, suggesting a need to identify other determinants of anemia without iron deficiency.Faculdade de Saúde Pública da Universidade de São Paulo2010-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102010000300015Revista de Saúde Pública v.44 n.3 2010reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USP10.1590/S0034-89102010000300015info:eu-repo/semantics/openAccessCarvalho,Antonio Geraldo CidrãoLira,Pedro Israel Cabral deBarros,Maria de Fátima AlcântaraAléssio,Maria Luiza MartinsLima,Marília de CarvalhoCarbonneau,Marie AnnetteBerger,JacquesLéger,Claude Louiseng2010-06-11T00:00:00Zoai:scielo:S0034-89102010000300015Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0034-8910&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.phprevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2010-06-11T00:00Revista de Saúde Pública - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Diagnosis of iron deficiency anemia in children of Northeast Brazil |
title |
Diagnosis of iron deficiency anemia in children of Northeast Brazil |
spellingShingle |
Diagnosis of iron deficiency anemia in children of Northeast Brazil Carvalho,Antonio Geraldo Cidrão Anemia, Iron Deficiency/diagnosis Ferritins/blood Laboratory Techniques and Procedures Hematologic Tests Iron Deficiency/prevention Iron Deficiency/control Infant Nutrition Child Nutrition |
title_short |
Diagnosis of iron deficiency anemia in children of Northeast Brazil |
title_full |
Diagnosis of iron deficiency anemia in children of Northeast Brazil |
title_fullStr |
Diagnosis of iron deficiency anemia in children of Northeast Brazil |
title_full_unstemmed |
Diagnosis of iron deficiency anemia in children of Northeast Brazil |
title_sort |
Diagnosis of iron deficiency anemia in children of Northeast Brazil |
author |
Carvalho,Antonio Geraldo Cidrão |
author_facet |
Carvalho,Antonio Geraldo Cidrão Lira,Pedro Israel Cabral de Barros,Maria de Fátima Alcântara Aléssio,Maria Luiza Martins Lima,Marília de Carvalho Carbonneau,Marie Annette Berger,Jacques Léger,Claude Louis |
author_role |
author |
author2 |
Lira,Pedro Israel Cabral de Barros,Maria de Fátima Alcântara Aléssio,Maria Luiza Martins Lima,Marília de Carvalho Carbonneau,Marie Annette Berger,Jacques Léger,Claude Louis |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Carvalho,Antonio Geraldo Cidrão Lira,Pedro Israel Cabral de Barros,Maria de Fátima Alcântara Aléssio,Maria Luiza Martins Lima,Marília de Carvalho Carbonneau,Marie Annette Berger,Jacques Léger,Claude Louis |
dc.subject.por.fl_str_mv |
Anemia, Iron Deficiency/diagnosis Ferritins/blood Laboratory Techniques and Procedures Hematologic Tests Iron Deficiency/prevention Iron Deficiency/control Infant Nutrition Child Nutrition |
topic |
Anemia, Iron Deficiency/diagnosis Ferritins/blood Laboratory Techniques and Procedures Hematologic Tests Iron Deficiency/prevention Iron Deficiency/control Infant Nutrition Child Nutrition |
description |
OBJECTIVE: To diagnose iron deficiency anemia in children. METHODS: The study was conducted with a sample of 301 children aged six to 30 months attending public daycare centers in the city of Recife, Northeast Brazil, in 2004. The diagnoses of anemia were based on a combination of different hematological and biochemical parameters: hemoglobin, mean corpuscular volume, ferritin, C-reactive protein, transferrin saturation and transferrin receptor. The chi-square test and ANOVA were used in the statistical analysis. RESULTS: Of all children studied, 92.4% had anemia (Hb <110 g/L) and 28.9% had moderate/severe anemia (Hb <90 g/L). Lower levels of hemoglobin were found in children aged 6-17 months. Iron deficiency was found in 51.5% of children using ferritin (<12 μg/L) as parameter. Taking into consideration the combination of hemoglobin level, ferritin and transferrin receptor, 58.1% had anemia with iron deficiency, 34.2% had anemia without iron deficiency and 2.3% had iron deficiency without anemia. Mean ferritin concentration was significantly higher in children with high C-reactive protein when compared with those with normal levels (22.1 vs. 14.8 µg/L). CONCLUSIONS: The use of several biochemical and hematological parameters allowed to diagnosing iron deficiency anemia in two thirds of children, suggesting a need to identify other determinants of anemia without iron deficiency. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102010000300015 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102010000300015 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0034-89102010000300015 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
dc.source.none.fl_str_mv |
Revista de Saúde Pública v.44 n.3 2010 reponame:Revista de Saúde Pública instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Revista de Saúde Pública |
collection |
Revista de Saúde Pública |
repository.name.fl_str_mv |
Revista de Saúde Pública - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
revsp@org.usp.br||revsp1@usp.br |
_version_ |
1748936499135512576 |