Diagnosis of iron deficiency anemia in children of Northeast Brazil

Detalhes bibliográficos
Autor(a) principal: Carvalho,Antonio Geraldo Cidrão
Data de Publicação: 2010
Outros Autores: Lira,Pedro Israel Cabral de, Barros,Maria de Fátima Alcântara, Aléssio,Maria Luiza Martins, Lima,Marília de Carvalho, Carbonneau,Marie Annette, Berger,Jacques, Léger,Claude Louis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Saúde Pública
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102010000300015
Resumo: OBJECTIVE: To diagnose iron deficiency anemia in children. METHODS: The study was conducted with a sample of 301 children aged six to 30 months attending public daycare centers in the city of Recife, Northeast Brazil, in 2004. The diagnoses of anemia were based on a combination of different hematological and biochemical parameters: hemoglobin, mean corpuscular volume, ferritin, C-reactive protein, transferrin saturation and transferrin receptor. The chi-square test and ANOVA were used in the statistical analysis. RESULTS: Of all children studied, 92.4% had anemia (Hb <110 g/L) and 28.9% had moderate/severe anemia (Hb <90 g/L). Lower levels of hemoglobin were found in children aged 6-17 months. Iron deficiency was found in 51.5% of children using ferritin (<12 μg/L) as parameter. Taking into consideration the combination of hemoglobin level, ferritin and transferrin receptor, 58.1% had anemia with iron deficiency, 34.2% had anemia without iron deficiency and 2.3% had iron deficiency without anemia. Mean ferritin concentration was significantly higher in children with high C-reactive protein when compared with those with normal levels (22.1 vs. 14.8 µg/L). CONCLUSIONS: The use of several biochemical and hematological parameters allowed to diagnosing iron deficiency anemia in two thirds of children, suggesting a need to identify other determinants of anemia without iron deficiency.
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spelling Diagnosis of iron deficiency anemia in children of Northeast BrazilAnemia, Iron Deficiency/diagnosisFerritins/bloodLaboratory Techniques and ProceduresHematologic TestsIron Deficiency/preventionIron Deficiency/controlInfant NutritionChild NutritionOBJECTIVE: To diagnose iron deficiency anemia in children. METHODS: The study was conducted with a sample of 301 children aged six to 30 months attending public daycare centers in the city of Recife, Northeast Brazil, in 2004. The diagnoses of anemia were based on a combination of different hematological and biochemical parameters: hemoglobin, mean corpuscular volume, ferritin, C-reactive protein, transferrin saturation and transferrin receptor. The chi-square test and ANOVA were used in the statistical analysis. RESULTS: Of all children studied, 92.4% had anemia (Hb <110 g/L) and 28.9% had moderate/severe anemia (Hb <90 g/L). Lower levels of hemoglobin were found in children aged 6-17 months. Iron deficiency was found in 51.5% of children using ferritin (<12 μg/L) as parameter. Taking into consideration the combination of hemoglobin level, ferritin and transferrin receptor, 58.1% had anemia with iron deficiency, 34.2% had anemia without iron deficiency and 2.3% had iron deficiency without anemia. Mean ferritin concentration was significantly higher in children with high C-reactive protein when compared with those with normal levels (22.1 vs. 14.8 µg/L). CONCLUSIONS: The use of several biochemical and hematological parameters allowed to diagnosing iron deficiency anemia in two thirds of children, suggesting a need to identify other determinants of anemia without iron deficiency.Faculdade de Saúde Pública da Universidade de São Paulo2010-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102010000300015Revista de Saúde Pública v.44 n.3 2010reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USP10.1590/S0034-89102010000300015info:eu-repo/semantics/openAccessCarvalho,Antonio Geraldo CidrãoLira,Pedro Israel Cabral deBarros,Maria de Fátima AlcântaraAléssio,Maria Luiza MartinsLima,Marília de CarvalhoCarbonneau,Marie AnnetteBerger,JacquesLéger,Claude Louiseng2010-06-11T00:00:00Zoai:scielo:S0034-89102010000300015Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0034-8910&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.phprevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2010-06-11T00:00Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Diagnosis of iron deficiency anemia in children of Northeast Brazil
title Diagnosis of iron deficiency anemia in children of Northeast Brazil
spellingShingle Diagnosis of iron deficiency anemia in children of Northeast Brazil
Carvalho,Antonio Geraldo Cidrão
Anemia, Iron Deficiency/diagnosis
Ferritins/blood
Laboratory Techniques and Procedures
Hematologic Tests
Iron Deficiency/prevention
Iron Deficiency/control
Infant Nutrition
Child Nutrition
title_short Diagnosis of iron deficiency anemia in children of Northeast Brazil
title_full Diagnosis of iron deficiency anemia in children of Northeast Brazil
title_fullStr Diagnosis of iron deficiency anemia in children of Northeast Brazil
title_full_unstemmed Diagnosis of iron deficiency anemia in children of Northeast Brazil
title_sort Diagnosis of iron deficiency anemia in children of Northeast Brazil
author Carvalho,Antonio Geraldo Cidrão
author_facet Carvalho,Antonio Geraldo Cidrão
Lira,Pedro Israel Cabral de
Barros,Maria de Fátima Alcântara
Aléssio,Maria Luiza Martins
Lima,Marília de Carvalho
Carbonneau,Marie Annette
Berger,Jacques
Léger,Claude Louis
author_role author
author2 Lira,Pedro Israel Cabral de
Barros,Maria de Fátima Alcântara
Aléssio,Maria Luiza Martins
Lima,Marília de Carvalho
Carbonneau,Marie Annette
Berger,Jacques
Léger,Claude Louis
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Carvalho,Antonio Geraldo Cidrão
Lira,Pedro Israel Cabral de
Barros,Maria de Fátima Alcântara
Aléssio,Maria Luiza Martins
Lima,Marília de Carvalho
Carbonneau,Marie Annette
Berger,Jacques
Léger,Claude Louis
dc.subject.por.fl_str_mv Anemia, Iron Deficiency/diagnosis
Ferritins/blood
Laboratory Techniques and Procedures
Hematologic Tests
Iron Deficiency/prevention
Iron Deficiency/control
Infant Nutrition
Child Nutrition
topic Anemia, Iron Deficiency/diagnosis
Ferritins/blood
Laboratory Techniques and Procedures
Hematologic Tests
Iron Deficiency/prevention
Iron Deficiency/control
Infant Nutrition
Child Nutrition
description OBJECTIVE: To diagnose iron deficiency anemia in children. METHODS: The study was conducted with a sample of 301 children aged six to 30 months attending public daycare centers in the city of Recife, Northeast Brazil, in 2004. The diagnoses of anemia were based on a combination of different hematological and biochemical parameters: hemoglobin, mean corpuscular volume, ferritin, C-reactive protein, transferrin saturation and transferrin receptor. The chi-square test and ANOVA were used in the statistical analysis. RESULTS: Of all children studied, 92.4% had anemia (Hb <110 g/L) and 28.9% had moderate/severe anemia (Hb <90 g/L). Lower levels of hemoglobin were found in children aged 6-17 months. Iron deficiency was found in 51.5% of children using ferritin (<12 μg/L) as parameter. Taking into consideration the combination of hemoglobin level, ferritin and transferrin receptor, 58.1% had anemia with iron deficiency, 34.2% had anemia without iron deficiency and 2.3% had iron deficiency without anemia. Mean ferritin concentration was significantly higher in children with high C-reactive protein when compared with those with normal levels (22.1 vs. 14.8 µg/L). CONCLUSIONS: The use of several biochemical and hematological parameters allowed to diagnosing iron deficiency anemia in two thirds of children, suggesting a need to identify other determinants of anemia without iron deficiency.
publishDate 2010
dc.date.none.fl_str_mv 2010-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102010000300015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102010000300015
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0034-89102010000300015
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
dc.source.none.fl_str_mv Revista de Saúde Pública v.44 n.3 2010
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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