Patient survival and risk of death after prostate cancer treatment in the Brazilian Unified Health System
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102017000100238 |
Resumo: | ABSTRACT OBJECTIVE Analyze the probability of specific survival and factors associated with the risk of death of patients with prostate cancer who received outpatient cancer treatment in the Brazilian Unified Health System, Brazil. METHODS Retrospective cohort study using the National Database of Oncology, developed through the deterministic-probabilistic pairing of health information systems: outpatient (SIA), hospital (SIH) and mortality (SIM). The probability of overall and specific survival was estimated by the time elapsed between the date of the first ambulatory treatment, from 2002 to 2003, until the patient’s death or the end of the study. Fine and Gray’s model of competing-risks regression was adjusted according to the variables: age of diagnostic, region of residence, tumor clinical staging, type of outpatient cancer treatment and hospitalization in the assessment of factors associated with risk of patient death. RESULTS Of 16,280 patients studied, the average age was 70 years, approximately 25% died due to prostate cancer and 20% for other causes. The probability of overall survival was 0.50 (95%CI 0.49–0.52) and the specific was 0.70 (95%CI 0.69–0.71). The factors associated with the risk of patient death were: stage III (HR = 1.66; 95%CI 1.39–1.99) and stage IV (HR = 3.49; 95%CI 2.91–4.18), chemotherapy (HR = 2.34; 95%CI 1.76–3.11) and hospitalization (HR = 1.6; 95%CI 1.55–1.79). CONCLUSIONS The late diagnosis of the tumor, palliative treatments, and worse medical condition were factors related to the worst survival and increased risk of death from prostate cancer patients in Brazil. |
id |
USP-23_bbebd12e804e4903ce113b992a2d7a52 |
---|---|
oai_identifier_str |
oai:scielo:S0034-89102017000100238 |
network_acronym_str |
USP-23 |
network_name_str |
Revista de Saúde Pública |
repository_id_str |
|
spelling |
Patient survival and risk of death after prostate cancer treatment in the Brazilian Unified Health SystemProstatic NeoplasmsMortalityRisk FactorsSurvivorship (Public Health)Men’s HealthUnified Health SystemABSTRACT OBJECTIVE Analyze the probability of specific survival and factors associated with the risk of death of patients with prostate cancer who received outpatient cancer treatment in the Brazilian Unified Health System, Brazil. METHODS Retrospective cohort study using the National Database of Oncology, developed through the deterministic-probabilistic pairing of health information systems: outpatient (SIA), hospital (SIH) and mortality (SIM). The probability of overall and specific survival was estimated by the time elapsed between the date of the first ambulatory treatment, from 2002 to 2003, until the patient’s death or the end of the study. Fine and Gray’s model of competing-risks regression was adjusted according to the variables: age of diagnostic, region of residence, tumor clinical staging, type of outpatient cancer treatment and hospitalization in the assessment of factors associated with risk of patient death. RESULTS Of 16,280 patients studied, the average age was 70 years, approximately 25% died due to prostate cancer and 20% for other causes. The probability of overall survival was 0.50 (95%CI 0.49–0.52) and the specific was 0.70 (95%CI 0.69–0.71). The factors associated with the risk of patient death were: stage III (HR = 1.66; 95%CI 1.39–1.99) and stage IV (HR = 3.49; 95%CI 2.91–4.18), chemotherapy (HR = 2.34; 95%CI 1.76–3.11) and hospitalization (HR = 1.6; 95%CI 1.55–1.79). CONCLUSIONS The late diagnosis of the tumor, palliative treatments, and worse medical condition were factors related to the worst survival and increased risk of death from prostate cancer patients in Brazil.Faculdade de Saúde Pública da Universidade de São Paulo2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102017000100238Revista de Saúde Pública v.51 2017reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USP10.1590/s1518-8787.2017051006766info:eu-repo/semantics/openAccessBraga,Sonia Faria MendesSouza,Mirian Carvalho deOliveira,Raphael Romie deAndrade,Eli Iola GurgelAcurcio,Francisco de AssisCherchiglia,Mariangela Lealeng2017-05-18T00:00:00Zoai:scielo:S0034-89102017000100238Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0034-8910&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.phprevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2017-05-18T00:00Revista de Saúde Pública - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Patient survival and risk of death after prostate cancer treatment in the Brazilian Unified Health System |
title |
Patient survival and risk of death after prostate cancer treatment in the Brazilian Unified Health System |
spellingShingle |
Patient survival and risk of death after prostate cancer treatment in the Brazilian Unified Health System Braga,Sonia Faria Mendes Prostatic Neoplasms Mortality Risk Factors Survivorship (Public Health) Men’s Health Unified Health System |
title_short |
Patient survival and risk of death after prostate cancer treatment in the Brazilian Unified Health System |
title_full |
Patient survival and risk of death after prostate cancer treatment in the Brazilian Unified Health System |
title_fullStr |
Patient survival and risk of death after prostate cancer treatment in the Brazilian Unified Health System |
title_full_unstemmed |
Patient survival and risk of death after prostate cancer treatment in the Brazilian Unified Health System |
title_sort |
Patient survival and risk of death after prostate cancer treatment in the Brazilian Unified Health System |
author |
Braga,Sonia Faria Mendes |
author_facet |
Braga,Sonia Faria Mendes Souza,Mirian Carvalho de Oliveira,Raphael Romie de Andrade,Eli Iola Gurgel Acurcio,Francisco de Assis Cherchiglia,Mariangela Leal |
author_role |
author |
author2 |
Souza,Mirian Carvalho de Oliveira,Raphael Romie de Andrade,Eli Iola Gurgel Acurcio,Francisco de Assis Cherchiglia,Mariangela Leal |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Braga,Sonia Faria Mendes Souza,Mirian Carvalho de Oliveira,Raphael Romie de Andrade,Eli Iola Gurgel Acurcio,Francisco de Assis Cherchiglia,Mariangela Leal |
dc.subject.por.fl_str_mv |
Prostatic Neoplasms Mortality Risk Factors Survivorship (Public Health) Men’s Health Unified Health System |
topic |
Prostatic Neoplasms Mortality Risk Factors Survivorship (Public Health) Men’s Health Unified Health System |
description |
ABSTRACT OBJECTIVE Analyze the probability of specific survival and factors associated with the risk of death of patients with prostate cancer who received outpatient cancer treatment in the Brazilian Unified Health System, Brazil. METHODS Retrospective cohort study using the National Database of Oncology, developed through the deterministic-probabilistic pairing of health information systems: outpatient (SIA), hospital (SIH) and mortality (SIM). The probability of overall and specific survival was estimated by the time elapsed between the date of the first ambulatory treatment, from 2002 to 2003, until the patient’s death or the end of the study. Fine and Gray’s model of competing-risks regression was adjusted according to the variables: age of diagnostic, region of residence, tumor clinical staging, type of outpatient cancer treatment and hospitalization in the assessment of factors associated with risk of patient death. RESULTS Of 16,280 patients studied, the average age was 70 years, approximately 25% died due to prostate cancer and 20% for other causes. The probability of overall survival was 0.50 (95%CI 0.49–0.52) and the specific was 0.70 (95%CI 0.69–0.71). The factors associated with the risk of patient death were: stage III (HR = 1.66; 95%CI 1.39–1.99) and stage IV (HR = 3.49; 95%CI 2.91–4.18), chemotherapy (HR = 2.34; 95%CI 1.76–3.11) and hospitalization (HR = 1.6; 95%CI 1.55–1.79). CONCLUSIONS The late diagnosis of the tumor, palliative treatments, and worse medical condition were factors related to the worst survival and increased risk of death from prostate cancer patients in Brazil. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102017000100238 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102017000100238 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s1518-8787.2017051006766 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
dc.source.none.fl_str_mv |
Revista de Saúde Pública v.51 2017 reponame:Revista de Saúde Pública instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Revista de Saúde Pública |
collection |
Revista de Saúde Pública |
repository.name.fl_str_mv |
Revista de Saúde Pública - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
revsp@org.usp.br||revsp1@usp.br |
_version_ |
1748936503854104576 |