HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population

Detalhes bibliográficos
Autor(a) principal: Soares,Bernadette Catalan
Data de Publicação: 2003
Outros Autores: Proietti,Anna Bárbara de F Carneiro, Proietti,Fernando Augusto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Saúde Pública
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102003000400012
Resumo: OBJECTIVE: Blood donors in Brazil have been routinely screened for HTLV-I/II since 1993. A study was performed to estimate the prevalence of HTLV-I/II infection in a low risk population and to better understand determinants associated with seropositivity. METHODS: HTLV-I/II seropositive (n=135), indeterminate (n=167) and seronegative blood donors (n=116) were enrolled in an open prevalence prospective cohort study. A cross-sectional epidemiological study of positive, indeterminate and seronegative HTLV-I/II subjects was conducted to assess behavioral and environmental risk factors for seropositivity. HTLV-I/II serological status was confirmed using enzyme-linked immunosorbent assay (EIA) and Western blot (WB). RESULTS: The three groups were not homogeneous. HTLV-I/II seropositivity was associated to past blood transfusion and years of schooling, a marker of socioeconomic status, and use of non-intravenous illegal drugs. CONCLUSIONS: The study results reinforce the importance of continuous monitoring and improvement of blood donor selection process.
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spelling HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk populationHTLV-I infections/bloodHTLV-II infections/bloodBlood donorsRisk factorsPrevalenceSerologic testsEnzyme-linked immunosorbent assayBlotWesternOBJECTIVE: Blood donors in Brazil have been routinely screened for HTLV-I/II since 1993. A study was performed to estimate the prevalence of HTLV-I/II infection in a low risk population and to better understand determinants associated with seropositivity. METHODS: HTLV-I/II seropositive (n=135), indeterminate (n=167) and seronegative blood donors (n=116) were enrolled in an open prevalence prospective cohort study. A cross-sectional epidemiological study of positive, indeterminate and seronegative HTLV-I/II subjects was conducted to assess behavioral and environmental risk factors for seropositivity. HTLV-I/II serological status was confirmed using enzyme-linked immunosorbent assay (EIA) and Western blot (WB). RESULTS: The three groups were not homogeneous. HTLV-I/II seropositivity was associated to past blood transfusion and years of schooling, a marker of socioeconomic status, and use of non-intravenous illegal drugs. CONCLUSIONS: The study results reinforce the importance of continuous monitoring and improvement of blood donor selection process.Faculdade de Saúde Pública da Universidade de São Paulo2003-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102003000400012Revista de Saúde Pública v.37 n.4 2003reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USP10.1590/S0034-89102003000400012info:eu-repo/semantics/openAccessSoares,Bernadette CatalanProietti,Anna Bárbara de F CarneiroProietti,Fernando Augustoeng2004-03-29T00:00:00Zoai:scielo:S0034-89102003000400012Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0034-8910&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.phprevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2004-03-29T00:00Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
title HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
spellingShingle HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
Soares,Bernadette Catalan
HTLV-I infections/blood
HTLV-II infections/blood
Blood donors
Risk factors
Prevalence
Serologic tests
Enzyme-linked immunosorbent assay
Blot
Western
title_short HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
title_full HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
title_fullStr HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
title_full_unstemmed HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
title_sort HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
author Soares,Bernadette Catalan
author_facet Soares,Bernadette Catalan
Proietti,Anna Bárbara de F Carneiro
Proietti,Fernando Augusto
author_role author
author2 Proietti,Anna Bárbara de F Carneiro
Proietti,Fernando Augusto
author2_role author
author
dc.contributor.author.fl_str_mv Soares,Bernadette Catalan
Proietti,Anna Bárbara de F Carneiro
Proietti,Fernando Augusto
dc.subject.por.fl_str_mv HTLV-I infections/blood
HTLV-II infections/blood
Blood donors
Risk factors
Prevalence
Serologic tests
Enzyme-linked immunosorbent assay
Blot
Western
topic HTLV-I infections/blood
HTLV-II infections/blood
Blood donors
Risk factors
Prevalence
Serologic tests
Enzyme-linked immunosorbent assay
Blot
Western
description OBJECTIVE: Blood donors in Brazil have been routinely screened for HTLV-I/II since 1993. A study was performed to estimate the prevalence of HTLV-I/II infection in a low risk population and to better understand determinants associated with seropositivity. METHODS: HTLV-I/II seropositive (n=135), indeterminate (n=167) and seronegative blood donors (n=116) were enrolled in an open prevalence prospective cohort study. A cross-sectional epidemiological study of positive, indeterminate and seronegative HTLV-I/II subjects was conducted to assess behavioral and environmental risk factors for seropositivity. HTLV-I/II serological status was confirmed using enzyme-linked immunosorbent assay (EIA) and Western blot (WB). RESULTS: The three groups were not homogeneous. HTLV-I/II seropositivity was associated to past blood transfusion and years of schooling, a marker of socioeconomic status, and use of non-intravenous illegal drugs. CONCLUSIONS: The study results reinforce the importance of continuous monitoring and improvement of blood donor selection process.
publishDate 2003
dc.date.none.fl_str_mv 2003-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102003000400012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102003000400012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0034-89102003000400012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
dc.source.none.fl_str_mv Revista de Saúde Pública v.37 n.4 2003
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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