HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
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Publication Date: | 2003 |
Other Authors: | , |
Format: | Article |
Language: | eng |
Source: | Revista de Saúde Pública |
Download full: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102003000400012 |
Summary: | OBJECTIVE: Blood donors in Brazil have been routinely screened for HTLV-I/II since 1993. A study was performed to estimate the prevalence of HTLV-I/II infection in a low risk population and to better understand determinants associated with seropositivity. METHODS: HTLV-I/II seropositive (n=135), indeterminate (n=167) and seronegative blood donors (n=116) were enrolled in an open prevalence prospective cohort study. A cross-sectional epidemiological study of positive, indeterminate and seronegative HTLV-I/II subjects was conducted to assess behavioral and environmental risk factors for seropositivity. HTLV-I/II serological status was confirmed using enzyme-linked immunosorbent assay (EIA) and Western blot (WB). RESULTS: The three groups were not homogeneous. HTLV-I/II seropositivity was associated to past blood transfusion and years of schooling, a marker of socioeconomic status, and use of non-intravenous illegal drugs. CONCLUSIONS: The study results reinforce the importance of continuous monitoring and improvement of blood donor selection process. |
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HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk populationHTLV-I infections/bloodHTLV-II infections/bloodBlood donorsRisk factorsPrevalenceSerologic testsEnzyme-linked immunosorbent assayBlotWesternOBJECTIVE: Blood donors in Brazil have been routinely screened for HTLV-I/II since 1993. A study was performed to estimate the prevalence of HTLV-I/II infection in a low risk population and to better understand determinants associated with seropositivity. METHODS: HTLV-I/II seropositive (n=135), indeterminate (n=167) and seronegative blood donors (n=116) were enrolled in an open prevalence prospective cohort study. A cross-sectional epidemiological study of positive, indeterminate and seronegative HTLV-I/II subjects was conducted to assess behavioral and environmental risk factors for seropositivity. HTLV-I/II serological status was confirmed using enzyme-linked immunosorbent assay (EIA) and Western blot (WB). RESULTS: The three groups were not homogeneous. HTLV-I/II seropositivity was associated to past blood transfusion and years of schooling, a marker of socioeconomic status, and use of non-intravenous illegal drugs. CONCLUSIONS: The study results reinforce the importance of continuous monitoring and improvement of blood donor selection process.Faculdade de Saúde Pública da Universidade de São Paulo2003-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102003000400012Revista de Saúde Pública v.37 n.4 2003reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USP10.1590/S0034-89102003000400012info:eu-repo/semantics/openAccessSoares,Bernadette CatalanProietti,Anna Bárbara de F CarneiroProietti,Fernando Augustoeng2004-03-29T00:00:00Zoai:scielo:S0034-89102003000400012Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0034-8910&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.phprevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2004-03-29T00:00Revista de Saúde Pública - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population |
title |
HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population |
spellingShingle |
HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population Soares,Bernadette Catalan HTLV-I infections/blood HTLV-II infections/blood Blood donors Risk factors Prevalence Serologic tests Enzyme-linked immunosorbent assay Blot Western |
title_short |
HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population |
title_full |
HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population |
title_fullStr |
HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population |
title_full_unstemmed |
HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population |
title_sort |
HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population |
author |
Soares,Bernadette Catalan |
author_facet |
Soares,Bernadette Catalan Proietti,Anna Bárbara de F Carneiro Proietti,Fernando Augusto |
author_role |
author |
author2 |
Proietti,Anna Bárbara de F Carneiro Proietti,Fernando Augusto |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Soares,Bernadette Catalan Proietti,Anna Bárbara de F Carneiro Proietti,Fernando Augusto |
dc.subject.por.fl_str_mv |
HTLV-I infections/blood HTLV-II infections/blood Blood donors Risk factors Prevalence Serologic tests Enzyme-linked immunosorbent assay Blot Western |
topic |
HTLV-I infections/blood HTLV-II infections/blood Blood donors Risk factors Prevalence Serologic tests Enzyme-linked immunosorbent assay Blot Western |
description |
OBJECTIVE: Blood donors in Brazil have been routinely screened for HTLV-I/II since 1993. A study was performed to estimate the prevalence of HTLV-I/II infection in a low risk population and to better understand determinants associated with seropositivity. METHODS: HTLV-I/II seropositive (n=135), indeterminate (n=167) and seronegative blood donors (n=116) were enrolled in an open prevalence prospective cohort study. A cross-sectional epidemiological study of positive, indeterminate and seronegative HTLV-I/II subjects was conducted to assess behavioral and environmental risk factors for seropositivity. HTLV-I/II serological status was confirmed using enzyme-linked immunosorbent assay (EIA) and Western blot (WB). RESULTS: The three groups were not homogeneous. HTLV-I/II seropositivity was associated to past blood transfusion and years of schooling, a marker of socioeconomic status, and use of non-intravenous illegal drugs. CONCLUSIONS: The study results reinforce the importance of continuous monitoring and improvement of blood donor selection process. |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102003000400012 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102003000400012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0034-89102003000400012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
dc.source.none.fl_str_mv |
Revista de Saúde Pública v.37 n.4 2003 reponame:Revista de Saúde Pública instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Revista de Saúde Pública |
collection |
Revista de Saúde Pública |
repository.name.fl_str_mv |
Revista de Saúde Pública - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
revsp@org.usp.br||revsp1@usp.br |
_version_ |
1748936493713326080 |