Maternal complications and cesarean section without indication: systematic review and meta-analysis

Detalhes bibliográficos
Autor(a) principal: Mascarello,Keila Cristina
Data de Publicação: 2017
Outros Autores: Horta,Bernardo Lessa, Silveira,Mariângela Freitas
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Saúde Pública
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102017000100504
Resumo: ABSTRACT OBJECTIVE The objective of this study was to determine the risks of severe acute maternal complications associated with cesarean section without medical indication. METHODS A systematic review was carried out with meta-analysis. The literature search was performed systematically, in multiple stages, in the PubMed, Lilacs, and Web of Science databases using the following descriptors: (postpartum period) and (cesarean section or natural childbirth) and ((morbidity or mortality) or (postpartum hemorrhage) or (puerperal infection) or (surgical infection) or (puerperal disorders)). The protocol of the study was registered at PROSPERO as CRD42016032933. A total of 1,328 articles were found; after selection, eight publications that met the study objective and inclusion criteria were selected, with information on 1,051,543 individuals. RESULTS The results obtained in the meta-analyses indicate that women with cesarean section have a higher chance of maternal death (OR = 3.10, 95%CI 1.92–5.00) and postpartum infection (OR = 2.83, 95%CI, 1.585.06), but they have a lower chance of hemorrhage (OR = 0.52, 95%CI 0.48–0.57). For the blood transfusion outcome, the group effect was not associated with the type of delivery (95%CI 0.88–2.81). CONCLUSIONS The quality of evidence was considered low for hemorrhage and blood transfusion and moderate for postpartum infection and maternal death. Thus, cesarean sections should be performed with caution and safety, especially when its benefits outweigh the risks of a surgical procedure.
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spelling Maternal complications and cesarean section without indication: systematic review and meta-analysisPuerperal Disorders, epidemiologyMaternal MortalityRisk FactorsCesarean Section, contraindicationsNatural ChildbirthMeta-AnalysisABSTRACT OBJECTIVE The objective of this study was to determine the risks of severe acute maternal complications associated with cesarean section without medical indication. METHODS A systematic review was carried out with meta-analysis. The literature search was performed systematically, in multiple stages, in the PubMed, Lilacs, and Web of Science databases using the following descriptors: (postpartum period) and (cesarean section or natural childbirth) and ((morbidity or mortality) or (postpartum hemorrhage) or (puerperal infection) or (surgical infection) or (puerperal disorders)). The protocol of the study was registered at PROSPERO as CRD42016032933. A total of 1,328 articles were found; after selection, eight publications that met the study objective and inclusion criteria were selected, with information on 1,051,543 individuals. RESULTS The results obtained in the meta-analyses indicate that women with cesarean section have a higher chance of maternal death (OR = 3.10, 95%CI 1.92–5.00) and postpartum infection (OR = 2.83, 95%CI, 1.585.06), but they have a lower chance of hemorrhage (OR = 0.52, 95%CI 0.48–0.57). For the blood transfusion outcome, the group effect was not associated with the type of delivery (95%CI 0.88–2.81). CONCLUSIONS The quality of evidence was considered low for hemorrhage and blood transfusion and moderate for postpartum infection and maternal death. Thus, cesarean sections should be performed with caution and safety, especially when its benefits outweigh the risks of a surgical procedure.Faculdade de Saúde Pública da Universidade de São Paulo2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102017000100504Revista de Saúde Pública v.51 2017reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USP10.11606/s1518-8787.2017051000389info:eu-repo/semantics/openAccessMascarello,Keila CristinaHorta,Bernardo LessaSilveira,Mariângela Freitaseng2017-11-14T00:00:00Zoai:scielo:S0034-89102017000100504Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0034-8910&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.phprevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2017-11-14T00:00Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Maternal complications and cesarean section without indication: systematic review and meta-analysis
title Maternal complications and cesarean section without indication: systematic review and meta-analysis
spellingShingle Maternal complications and cesarean section without indication: systematic review and meta-analysis
Mascarello,Keila Cristina
Puerperal Disorders, epidemiology
Maternal Mortality
Risk Factors
Cesarean Section, contraindications
Natural Childbirth
Meta-Analysis
title_short Maternal complications and cesarean section without indication: systematic review and meta-analysis
title_full Maternal complications and cesarean section without indication: systematic review and meta-analysis
title_fullStr Maternal complications and cesarean section without indication: systematic review and meta-analysis
title_full_unstemmed Maternal complications and cesarean section without indication: systematic review and meta-analysis
title_sort Maternal complications and cesarean section without indication: systematic review and meta-analysis
author Mascarello,Keila Cristina
author_facet Mascarello,Keila Cristina
Horta,Bernardo Lessa
Silveira,Mariângela Freitas
author_role author
author2 Horta,Bernardo Lessa
Silveira,Mariângela Freitas
author2_role author
author
dc.contributor.author.fl_str_mv Mascarello,Keila Cristina
Horta,Bernardo Lessa
Silveira,Mariângela Freitas
dc.subject.por.fl_str_mv Puerperal Disorders, epidemiology
Maternal Mortality
Risk Factors
Cesarean Section, contraindications
Natural Childbirth
Meta-Analysis
topic Puerperal Disorders, epidemiology
Maternal Mortality
Risk Factors
Cesarean Section, contraindications
Natural Childbirth
Meta-Analysis
description ABSTRACT OBJECTIVE The objective of this study was to determine the risks of severe acute maternal complications associated with cesarean section without medical indication. METHODS A systematic review was carried out with meta-analysis. The literature search was performed systematically, in multiple stages, in the PubMed, Lilacs, and Web of Science databases using the following descriptors: (postpartum period) and (cesarean section or natural childbirth) and ((morbidity or mortality) or (postpartum hemorrhage) or (puerperal infection) or (surgical infection) or (puerperal disorders)). The protocol of the study was registered at PROSPERO as CRD42016032933. A total of 1,328 articles were found; after selection, eight publications that met the study objective and inclusion criteria were selected, with information on 1,051,543 individuals. RESULTS The results obtained in the meta-analyses indicate that women with cesarean section have a higher chance of maternal death (OR = 3.10, 95%CI 1.92–5.00) and postpartum infection (OR = 2.83, 95%CI, 1.585.06), but they have a lower chance of hemorrhage (OR = 0.52, 95%CI 0.48–0.57). For the blood transfusion outcome, the group effect was not associated with the type of delivery (95%CI 0.88–2.81). CONCLUSIONS The quality of evidence was considered low for hemorrhage and blood transfusion and moderate for postpartum infection and maternal death. Thus, cesarean sections should be performed with caution and safety, especially when its benefits outweigh the risks of a surgical procedure.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102017000100504
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102017000100504
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.11606/s1518-8787.2017051000389
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
dc.source.none.fl_str_mv Revista de Saúde Pública v.51 2017
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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