Dermatological disease among HIV-infected patients with CD4-lymphocyte count

Detalhes bibliográficos
Autor(a) principal: Michelim, Lessandra
Data de Publicação: 2004
Outros Autores: Atti, José Luiz, Panarotto, Daniel, Lovatto, Louise, Boniatti, Márcio Manozzo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/31811
Resumo: OBJECTIVE: To correlate the prevalence of dermatological diseases among HIV-infected patient with CD4-lymphocyte count. METHODS: A case series study was carried out in the region of Caxias do Sul, state of Rio Grande do Sul State, Brazil. Data was collected by reviewing the records of HIV-infected patients admitted to a public hospital (198 patients from March 1998 to June 2002) or seen at the university outpatient clinic (40 patients from March to June 2002). The variables analyzed were: age, sex, CD4-lymphocyte count, viral load, and dermatological diseases. Statistical analyses were performed using Student's t-test, Spearman's and Chi-Square tests. RESULTS: The frequency of dermatological disease was 67.2% among hospitalized patients and 75.0% among outpatients. Oral candidiasis was the most prevalent dermatological disease. Among the hospital population, the average CD4 count was lower among patients with dermatological disease than among those with no disease (142.34 cells/mm³ vs 512.35 cells/mm³, respectively; p=0.018). The same phenomenon was observed in outpatient population (138.88 cells/mm³ and 336.21 cells/mm³, respectively; p=0.001). In both populations, a negative correlation was found between CD4 count and the total number of dermatological diseases by a patient (p=0.000, hospital population, p=0.000, outpatient population). CONCLUSIONS: Dermatological diseases are highly prevalent among HIV-infected patients and the frequency and number of these manifestations are well correlated to the patient's immune status and disease progression.
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spelling Dermatological disease among HIV-infected patients with CD4-lymphocyte count Dermatoses em pacientes infectados pelo HIV com a contagem de linfócitos CD4 Infecções por HIVSíndrome de imunodeficiência adquiridaInfecções oportunistas relacionadas com a AidsDermatopatiasContagem de linfócito CD4ImunossupressãoHIV infectionsAcquired immunodeficiency syndromeAIDS-related opportunistic infectionsSkin diseasesCD4-lymphocyte countImmunosuppression OBJECTIVE: To correlate the prevalence of dermatological diseases among HIV-infected patient with CD4-lymphocyte count. METHODS: A case series study was carried out in the region of Caxias do Sul, state of Rio Grande do Sul State, Brazil. Data was collected by reviewing the records of HIV-infected patients admitted to a public hospital (198 patients from March 1998 to June 2002) or seen at the university outpatient clinic (40 patients from March to June 2002). The variables analyzed were: age, sex, CD4-lymphocyte count, viral load, and dermatological diseases. Statistical analyses were performed using Student's t-test, Spearman's and Chi-Square tests. RESULTS: The frequency of dermatological disease was 67.2% among hospitalized patients and 75.0% among outpatients. Oral candidiasis was the most prevalent dermatological disease. Among the hospital population, the average CD4 count was lower among patients with dermatological disease than among those with no disease (142.34 cells/mm³ vs 512.35 cells/mm³, respectively; p=0.018). The same phenomenon was observed in outpatient population (138.88 cells/mm³ and 336.21 cells/mm³, respectively; p=0.001). In both populations, a negative correlation was found between CD4 count and the total number of dermatological diseases by a patient (p=0.000, hospital population, p=0.000, outpatient population). CONCLUSIONS: Dermatological diseases are highly prevalent among HIV-infected patients and the frequency and number of these manifestations are well correlated to the patient's immune status and disease progression. OBJETIVO: Correlacionar a prevalência das doenças dermatológicas entre pacientes infectados pelo HIV com a contagem de linfócitos CD4. MÉTODOS: Estudo de série de casos realizado na região de Caxias do Sul, Estado do Rio Grande do Sul. Os dados foram coletados por meio da revisão de prontuários de pacientes com infecção pelo HIV internados em hospital público (198 pacientes, período de março de 1998 a junho de 2002) ou atendidos no ambulatório central universitário (40 pacientes, período de março a junho de 2002). As variáveis analisadas foram: idade, sexo, contagem de linfócitos CD4, carga viral e doenças dermatológicas apresentadas pelo paciente. Os testes estatísticos utilizados foram o Teste t de Student, o de Spearman e o do qui-quadrado. RESULTADOS: A freqüência de doença dermatológica foi de 67,2% entre os pacientes hospitalizados e de 75,0% entre os pacientes ambulatoriais. Candidíase oral foi a doença dermatológica mais prevalente. Na população hospitalar, a média de células CD4 foi menor entre os pacientes com doença dermatológica dos sem doença dermatológica (142,34 células/mm³ vs 512,35 células/mm³, respectivamente; p=0,018). O mesmo fenômeno foi observado na população ambulatorial (138,88 células/mm³ e 336,21 células/mm³, respectivamente; p=0,001). Verificou-se, em ambas as populações, uma correlação negativa entre a contagem de CD4 e o número total de doenças dermatológicas apresentadas pelo paciente (p=0,000, população hospitalar; p=0,000, população ambulatorial). CONCLUSÕES: As doenças dermatológicas são altamente prevalentes entre os pacientes infectados pelo HIV, sendo que a freqüência e o número dessas manifestações correlacionam-se bem com o status imunológico do paciente e com a progressão da doença. Universidade de São Paulo. Faculdade de Saúde Pública2004-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/3181110.1590/S0034-89102004000600002Revista de Saúde Pública; Vol. 38 No. 6 (2004); 758-763 Revista de Saúde Pública; Vol. 38 Núm. 6 (2004); 758-763 Revista de Saúde Pública; v. 38 n. 6 (2004); 758-763 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/31811/33743Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessMichelim, LessandraAtti, José LuizPanarotto, DanielLovatto, LouiseBoniatti, Márcio Manozzo2012-07-08T22:12:46Zoai:revistas.usp.br:article/31811Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-07-08T22:12:46Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Dermatological disease among HIV-infected patients with CD4-lymphocyte count
Dermatoses em pacientes infectados pelo HIV com a contagem de linfócitos CD4
title Dermatological disease among HIV-infected patients with CD4-lymphocyte count
spellingShingle Dermatological disease among HIV-infected patients with CD4-lymphocyte count
Michelim, Lessandra
Infecções por HIV
Síndrome de imunodeficiência adquirida
Infecções oportunistas relacionadas com a Aids
Dermatopatias
Contagem de linfócito CD4
Imunossupressão
HIV infections
Acquired immunodeficiency syndrome
AIDS-related opportunistic infections
Skin diseases
CD4-lymphocyte count
Immunosuppression
title_short Dermatological disease among HIV-infected patients with CD4-lymphocyte count
title_full Dermatological disease among HIV-infected patients with CD4-lymphocyte count
title_fullStr Dermatological disease among HIV-infected patients with CD4-lymphocyte count
title_full_unstemmed Dermatological disease among HIV-infected patients with CD4-lymphocyte count
title_sort Dermatological disease among HIV-infected patients with CD4-lymphocyte count
author Michelim, Lessandra
author_facet Michelim, Lessandra
Atti, José Luiz
Panarotto, Daniel
Lovatto, Louise
Boniatti, Márcio Manozzo
author_role author
author2 Atti, José Luiz
Panarotto, Daniel
Lovatto, Louise
Boniatti, Márcio Manozzo
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Michelim, Lessandra
Atti, José Luiz
Panarotto, Daniel
Lovatto, Louise
Boniatti, Márcio Manozzo
dc.subject.por.fl_str_mv Infecções por HIV
Síndrome de imunodeficiência adquirida
Infecções oportunistas relacionadas com a Aids
Dermatopatias
Contagem de linfócito CD4
Imunossupressão
HIV infections
Acquired immunodeficiency syndrome
AIDS-related opportunistic infections
Skin diseases
CD4-lymphocyte count
Immunosuppression
topic Infecções por HIV
Síndrome de imunodeficiência adquirida
Infecções oportunistas relacionadas com a Aids
Dermatopatias
Contagem de linfócito CD4
Imunossupressão
HIV infections
Acquired immunodeficiency syndrome
AIDS-related opportunistic infections
Skin diseases
CD4-lymphocyte count
Immunosuppression
description OBJECTIVE: To correlate the prevalence of dermatological diseases among HIV-infected patient with CD4-lymphocyte count. METHODS: A case series study was carried out in the region of Caxias do Sul, state of Rio Grande do Sul State, Brazil. Data was collected by reviewing the records of HIV-infected patients admitted to a public hospital (198 patients from March 1998 to June 2002) or seen at the university outpatient clinic (40 patients from March to June 2002). The variables analyzed were: age, sex, CD4-lymphocyte count, viral load, and dermatological diseases. Statistical analyses were performed using Student's t-test, Spearman's and Chi-Square tests. RESULTS: The frequency of dermatological disease was 67.2% among hospitalized patients and 75.0% among outpatients. Oral candidiasis was the most prevalent dermatological disease. Among the hospital population, the average CD4 count was lower among patients with dermatological disease than among those with no disease (142.34 cells/mm³ vs 512.35 cells/mm³, respectively; p=0.018). The same phenomenon was observed in outpatient population (138.88 cells/mm³ and 336.21 cells/mm³, respectively; p=0.001). In both populations, a negative correlation was found between CD4 count and the total number of dermatological diseases by a patient (p=0.000, hospital population, p=0.000, outpatient population). CONCLUSIONS: Dermatological diseases are highly prevalent among HIV-infected patients and the frequency and number of these manifestations are well correlated to the patient's immune status and disease progression.
publishDate 2004
dc.date.none.fl_str_mv 2004-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/31811
10.1590/S0034-89102004000600002
url https://www.revistas.usp.br/rsp/article/view/31811
identifier_str_mv 10.1590/S0034-89102004000600002
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/31811/33743
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 38 No. 6 (2004); 758-763
Revista de Saúde Pública; Vol. 38 Núm. 6 (2004); 758-763
Revista de Saúde Pública; v. 38 n. 6 (2004); 758-763
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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