Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Andréa Pinto Leite
Data de Publicação: 2015
Outros Autores: Oliveira, Beatriz Guitton Renaud Baptista de, Soares, Marja Ferreira, Barreto, Bruna Maiara Ferreira, Futuro, Débora Omena, Castilho, Selma Rodrigues de
Tipo de documento: Artigo
Idioma: eng
por
Título da fonte: Revista da Escola de Enfermagem da USP (Online)
Texto Completo: https://www.revistas.usp.br/reeusp/article/view/103220
Resumo: OBJECTIVE To analyze the effectiveness of 2% and 4% papain gels in tissue repair of venous ulcers. METHOD Quasi-experimental study with consecutive sample of 16 patients with 30 venous ulcers treated at the outpatient clinic of a teaching hospital, from April to November in 2011, using a form for clinical assessment of the patient and its lesion. Variables were analyzed by Wilcoxon and McNemar test (p < 0.05). RESULTS Most participants were female; aged between 51 and 59 years; obese; with hypertension. Regarding ulcers, there was an average decrease of 7.9 cm2 (50% of its original size) in 90 days; 20% of the ulcers completely healed within 56.67 days. There was an increase in epithelialization, significant reduction in the slough and edema, improved depth, in the type and amount of exudate (p < 0.0001). CONCLUSION 2% and 4% papain gels were effective in healing venous ulcers.
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spelling Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers Efetividade Dos Géis De Papaína A 2% E 4% Na Cicatrização De Úlceras Venosas Efectividad De Los Geles De Papaína Al 2% Y Al 4% En La Cicatrización De Úlceras Venosas OBJECTIVE To analyze the effectiveness of 2% and 4% papain gels in tissue repair of venous ulcers. METHOD Quasi-experimental study with consecutive sample of 16 patients with 30 venous ulcers treated at the outpatient clinic of a teaching hospital, from April to November in 2011, using a form for clinical assessment of the patient and its lesion. Variables were analyzed by Wilcoxon and McNemar test (p < 0.05). RESULTS Most participants were female; aged between 51 and 59 years; obese; with hypertension. Regarding ulcers, there was an average decrease of 7.9 cm2 (50% of its original size) in 90 days; 20% of the ulcers completely healed within 56.67 days. There was an increase in epithelialization, significant reduction in the slough and edema, improved depth, in the type and amount of exudate (p < 0.0001). CONCLUSION 2% and 4% papain gels were effective in healing venous ulcers. OBJETIVO Analisar a efetividade dos géis de papaína a 2% e 4% no reparo tecidual das úlceras venosas. MÉTODO Estudo quase-experimental, com amostra consecutiva de 16 pacientes com 30 úlceras venosas, atendidos no ambulatório de um hospital universitário, de abril a novembro de 2011, com formulário para avaliação clínica do paciente e da lesão. Variáveis analisadas pelos testes de Wilcoxon e McNemar (p < 0,05). RESULTADOS Predomínio do sexo feminino; idade entre 51 e 59 anos; obesas; com Hipertensão Arterial Sistêmica. Quanto às úlceras, houve redução média de 7,9 cm2 (50% do tamanho) em 90 dias; 20% cicatrizaram completamente em 56,67 dias. Houve aumento da epitelização, redução significativa do esfacelo e do edema, melhora na profundidade, no tipo e na quantidade de exsudato (p < 0,0001). CONCLUSÃO Os géis de papaína a 2% e 4% foram efetivos na cicatrização de úlceras venosas. OBJETIVO Analizar la efectividad de los geles de papaína al 2% y al 4% en la reparación del tejido de las úlceras venosas. MÉTODO Estudio cuasi-experimental, con muestra consecutiva de 16 pacientes con 30 úlceras venosas, atendidos en el ambulatorio de un hospital universitario, de abril a noviembre de 2011, con formulario para evaluación clínica del paciente y la lesión. Variables analizadas por las pruebas de Wilcoxon y McNemar (p < 0,05). RESULTADOS Predominio del sexo femenino; edad entre 51 y 59 años; obesas; con Hipertensión Arterial Sistémica. En cuanto a las úlceras, hubo reducción media de 7,9 cm2 (el 50% del tamaño) en 90 días; el 20% cicatrizaron completamente en 56,67 días. Hubo incremento de la epitelización, reducción significativa de la esfacelación y el edema, mejora en la profundidad, la clase y la cantidad de exudado (p < 0,0001). CONCLUSIÓN Los geles de papaína al 2% y al 4% fueron efectivos en la cicatrización de úlceras venosas. Universidade de São Paulo. Escola de Enfermagem2015-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://www.revistas.usp.br/reeusp/article/view/10322010.1590/S0080-623420150000300006Revista da Escola de Enfermagem da USP; v. 49 n. 3 (2015); 394-400Revista da Escola de Enfermagem da USP; Vol. 49 No. 3 (2015); 394-400Revista da Escola de Enfermagem da USP; Vol. 49 Núm. 3 (2015); 394-4001980-220X0080-6234reponame:Revista da Escola de Enfermagem da USP (Online)instname:Universidade de São Paulo (USP)instacron:USPengporhttps://www.revistas.usp.br/reeusp/article/view/103220/101637https://www.revistas.usp.br/reeusp/article/view/103220/101638http://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessRibeiro, Andréa Pinto Leite Oliveira, Beatriz Guitton Renaud Baptista de Soares, Marja Ferreira Barreto, Bruna Maiara Ferreira Futuro, Débora Omena Castilho, Selma Rodrigues de 2015-09-01T20:29:09Zoai:revistas.usp.br:article/103220Revistahttps://www.revistas.usp.br/reeuspPUBhttps://www.revistas.usp.br/reeusp/oai||nursingscholar@usp.br1980-220X0080-6234opendoar:2015-09-01T20:29:09Revista da Escola de Enfermagem da USP (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers
Efetividade Dos Géis De Papaína A 2% E 4% Na Cicatrização De Úlceras Venosas
Efectividad De Los Geles De Papaína Al 2% Y Al 4% En La Cicatrización De Úlceras Venosas
title Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers
spellingShingle Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers
Ribeiro, Andréa Pinto Leite
title_short Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers
title_full Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers
title_fullStr Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers
title_full_unstemmed Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers
title_sort Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers
author Ribeiro, Andréa Pinto Leite
author_facet Ribeiro, Andréa Pinto Leite
Oliveira, Beatriz Guitton Renaud Baptista de
Soares, Marja Ferreira
Barreto, Bruna Maiara Ferreira
Futuro, Débora Omena
Castilho, Selma Rodrigues de
author_role author
author2 Oliveira, Beatriz Guitton Renaud Baptista de
Soares, Marja Ferreira
Barreto, Bruna Maiara Ferreira
Futuro, Débora Omena
Castilho, Selma Rodrigues de
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Ribeiro, Andréa Pinto Leite
Oliveira, Beatriz Guitton Renaud Baptista de
Soares, Marja Ferreira
Barreto, Bruna Maiara Ferreira
Futuro, Débora Omena
Castilho, Selma Rodrigues de
description OBJECTIVE To analyze the effectiveness of 2% and 4% papain gels in tissue repair of venous ulcers. METHOD Quasi-experimental study with consecutive sample of 16 patients with 30 venous ulcers treated at the outpatient clinic of a teaching hospital, from April to November in 2011, using a form for clinical assessment of the patient and its lesion. Variables were analyzed by Wilcoxon and McNemar test (p < 0.05). RESULTS Most participants were female; aged between 51 and 59 years; obese; with hypertension. Regarding ulcers, there was an average decrease of 7.9 cm2 (50% of its original size) in 90 days; 20% of the ulcers completely healed within 56.67 days. There was an increase in epithelialization, significant reduction in the slough and edema, improved depth, in the type and amount of exudate (p < 0.0001). CONCLUSION 2% and 4% papain gels were effective in healing venous ulcers.
publishDate 2015
dc.date.none.fl_str_mv 2015-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/reeusp/article/view/103220
10.1590/S0080-623420150000300006
url https://www.revistas.usp.br/reeusp/article/view/103220
identifier_str_mv 10.1590/S0080-623420150000300006
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/reeusp/article/view/103220/101637
https://www.revistas.usp.br/reeusp/article/view/103220/101638
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Escola de Enfermagem
publisher.none.fl_str_mv Universidade de São Paulo. Escola de Enfermagem
dc.source.none.fl_str_mv Revista da Escola de Enfermagem da USP; v. 49 n. 3 (2015); 394-400
Revista da Escola de Enfermagem da USP; Vol. 49 No. 3 (2015); 394-400
Revista da Escola de Enfermagem da USP; Vol. 49 Núm. 3 (2015); 394-400
1980-220X
0080-6234
reponame:Revista da Escola de Enfermagem da USP (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista da Escola de Enfermagem da USP (Online)
collection Revista da Escola de Enfermagem da USP (Online)
repository.name.fl_str_mv Revista da Escola de Enfermagem da USP (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||nursingscholar@usp.br
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