Cellular exudation induced by carrageenan in the peritoneal cavity of chicks

• Autor(a) principal: Madeira, Alda Maria Backx Noronha
• Data de Publicação: 1997
• Outros Autores: Ito, Nair Massako Katayama
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
• Texto Completo: https://www.revistas.usp.br/bjvras/article/view/50341
• topic: Carragenina; Inflamação; Exsudatos; Contagem de células; Galinhas.; Carrageenan; Inflammation; Exudates; Cell counting; Hens

The cellular response, induced by the carrageenan injection (4.5 ml; 0.2% w/v) in Ringer-Locke solution into the peritoneal cavity of chicks (three to six-week old Isa Brown males), was evaluated by total and differential inflammatory cell counting of exudates collected 0.5 to 4 hours after stimulus. An increased leucocyte exudation, with predominance of heterophils, wasobserved within 1 and 4 hours post-stimulus. Macrophages were the second predominant cell type, followed by lymphocytes, eosinophils and basophils, in decreasing order. Thrombocytes were not significant in the peritoneal inflammatory exudate. Results presented in this work indicate that the peritoneal cavity can be utilized as a good model for studying the acuteinflammatory response of chickens.