Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells

Detalhes bibliográficos
Autor(a) principal: Ogata, Terezinha Regina Prúpere
Data de Publicação: 1997
Outros Autores: Guerra, José Luiz, Hernandez, Francisco Javier
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
Texto Completo: https://www.revistas.usp.br/bjvras/article/view/50294
Resumo: A comparative study of metastic and primitive tumors extra-celular matrix in nude rats, xenotransplanted with KB cells, using histochemical methods, was carried out. In both primitive and metastatic tumors it was possible to observe a qualitative and a quantitative variation of matricial components; coexistence of different kinds of fibers; small representation of elastic fibers; presence of acid and sulfated glycosaminoglycans and neutral polysacharyds, and also absence of basal membrane. It is suggested a small interaction between collagenic components and proteoglycan of primary tumors and the proteoglycan, whereas in métastasés this interaction is increased.
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spelling Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cellsEstudo histoquímico comparativo da matriz extracelular dc tumores primários e metastáticos em ratos nude xenotransplantados com células KBMatriz extracelularCélulas KBHistoquímicaRatos nudeExtracellular matrixKB cellsHistochemicalNude ratsA comparative study of metastic and primitive tumors extra-celular matrix in nude rats, xenotransplanted with KB cells, using histochemical methods, was carried out. In both primitive and metastatic tumors it was possible to observe a qualitative and a quantitative variation of matricial components; coexistence of different kinds of fibers; small representation of elastic fibers; presence of acid and sulfated glycosaminoglycans and neutral polysacharyds, and also absence of basal membrane. It is suggested a small interaction between collagenic components and proteoglycan of primary tumors and the proteoglycan, whereas in métastasés this interaction is increased.Estudou-se comparativamente, através de métodos histoquímicos, a expressão dos componentes da matriz extracelular de tumores primitivos e metastáticos em ratos nude, xenotransplantados com células KB. Em ambas as neoplasias observou-se uma variabilidade tanto qualitativa como quantitativa dos componentes matriciais, coexistência de diferentes tipos de fibras, pouca representatividade de fibras elásticas de glicosaminoglicanas ácidas e sulfatadas e de polissacarídeos neutros, além da ausência de membrana basal.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia1997-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/5029410.11606/issn.2318-3659.v34i4p203-206Brazilian Journal of Veterinary Research and Animal Science; Vol. 34 Núm. 4 (1997); 203-206Brazilian Journal of Veterinary Research and Animal Science; Vol. 34 No. 4 (1997); 203-206Brazilian Journal of Veterinary Research and Animal Science; v. 34 n. 4 (1997); 203-206Brazilian Journal of Veterinary Research and Animal Science; V. 34 N. 4 (1997); 203-2061678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPenghttps://www.revistas.usp.br/bjvras/article/view/50294/54407Ogata, Terezinha Regina PrúpereGuerra, José LuizHernandez, Francisco Javierinfo:eu-repo/semantics/openAccess2020-06-23T04:47:49Zoai:revistas.usp.br:article/50294Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:43:18.687419Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false
dc.title.none.fl_str_mv Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells
Estudo histoquímico comparativo da matriz extracelular dc tumores primários e metastáticos em ratos nude xenotransplantados com células KB
title Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells
spellingShingle Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells
Ogata, Terezinha Regina Prúpere
Matriz extracelular
Células KB
Histoquímica
Ratos nude
Extracellular matrix
KB cells
Histochemical
Nude rats
title_short Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells
title_full Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells
title_fullStr Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells
title_full_unstemmed Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells
title_sort Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells
author Ogata, Terezinha Regina Prúpere
author_facet Ogata, Terezinha Regina Prúpere
Guerra, José Luiz
Hernandez, Francisco Javier
author_role author
author2 Guerra, José Luiz
Hernandez, Francisco Javier
author2_role author
author
dc.contributor.author.fl_str_mv Ogata, Terezinha Regina Prúpere
Guerra, José Luiz
Hernandez, Francisco Javier
dc.subject.por.fl_str_mv Matriz extracelular
Células KB
Histoquímica
Ratos nude
Extracellular matrix
KB cells
Histochemical
Nude rats
topic Matriz extracelular
Células KB
Histoquímica
Ratos nude
Extracellular matrix
KB cells
Histochemical
Nude rats
description A comparative study of metastic and primitive tumors extra-celular matrix in nude rats, xenotransplanted with KB cells, using histochemical methods, was carried out. In both primitive and metastatic tumors it was possible to observe a qualitative and a quantitative variation of matricial components; coexistence of different kinds of fibers; small representation of elastic fibers; presence of acid and sulfated glycosaminoglycans and neutral polysacharyds, and also absence of basal membrane. It is suggested a small interaction between collagenic components and proteoglycan of primary tumors and the proteoglycan, whereas in métastasés this interaction is increased.
publishDate 1997
dc.date.none.fl_str_mv 1997-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/50294
10.11606/issn.2318-3659.v34i4p203-206
url https://www.revistas.usp.br/bjvras/article/view/50294
identifier_str_mv 10.11606/issn.2318-3659.v34i4p203-206
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/50294/54407
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science; Vol. 34 Núm. 4 (1997); 203-206
Brazilian Journal of Veterinary Research and Animal Science; Vol. 34 No. 4 (1997); 203-206
Brazilian Journal of Veterinary Research and Animal Science; v. 34 n. 4 (1997); 203-206
Brazilian Journal of Veterinary Research and Animal Science; V. 34 N. 4 (1997); 203-206
1678-4456
1413-9596
reponame:Brazilian Journal of Veterinary Research and Animal Science
instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron:USP
instname_str Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Veterinary Research and Animal Science
collection Brazilian Journal of Veterinary Research and Animal Science
repository.name.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
repository.mail.fl_str_mv bjvras@usp.br
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