Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor

Detalhes bibliográficos
Autor(a) principal: Barcelos, Ricardo
Data de Publicação: 2007
Outros Autores: Faria, Juliano, Grossi, Paulo, Aparício, Marco Antonio Moscoso, Bottino, Cássio M. C.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Archives of Clinical Psychiatry
Texto Completo: https://www.revistas.usp.br/acp/article/view/17084
Resumo: CONTEXT: Among neuropsychiatric disorders caused by cerebrovascular factors, vascular depression is diagnosed in a small degree by general practitioners, causing morbid-mortality increase in elderly. CASE REPORT: That is a case of a 67 year-old-man with partial response after treatment with a Selective Serotonin Receptors Inhibitor, and severe autonomic adverse effects with other antidepressants. The addition of rivastigmine to citalopram resulted in a therapeutic success, with a reduction of 23 to 7 points on the Hamilton Depressive Scale (HAM-D). DISCUSSION: The result obtained brings new perspectives to the treatment of vascular depression, providing that randomized controlled trials with larger sample sizes confirm the positive effect of the addition of a cholinesterase inhibitor to antidepressants in the treatment of these patients.
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spelling Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor Depressão vascular no idoso: resposta ao tratamento antidepressivo associado a inibidor das colinesterases Vascular depressionvascular dementiaAlzheimer's diseasestrokeneuroimagingDepressão vasculardemência vasculardoença de AlzheimerAVCneuroimagem CONTEXT: Among neuropsychiatric disorders caused by cerebrovascular factors, vascular depression is diagnosed in a small degree by general practitioners, causing morbid-mortality increase in elderly. CASE REPORT: That is a case of a 67 year-old-man with partial response after treatment with a Selective Serotonin Receptors Inhibitor, and severe autonomic adverse effects with other antidepressants. The addition of rivastigmine to citalopram resulted in a therapeutic success, with a reduction of 23 to 7 points on the Hamilton Depressive Scale (HAM-D). DISCUSSION: The result obtained brings new perspectives to the treatment of vascular depression, providing that randomized controlled trials with larger sample sizes confirm the positive effect of the addition of a cholinesterase inhibitor to antidepressants in the treatment of these patients. CONTEXTO: Entre os transtornos neuropsiquiátricos ocasionados por eventos cerebrovasculares, a depressão vascular é pouco diagnosticada por médicos não especialistas, causando aumento da morbimortalidade de pacientes idosos. CASO CLÍNICO: Trata-se de um paciente com 67 anos que apresentou resposta parcial a tratamento com inibidores da recaptura de serotonina e efeitos adversos autonômicos graves com outros antidepressivos. A adição de rivastigmina ao citalopram promoveu sucesso terapêutico, com redução de 23 para 7 pontos, na escala de Hamilton para depressão. DISCUSSÃO: O resultado obtido traz novas perspectivas para o tratamento da depressão vascular, sendo necessários ensaios clínicos controlados que evidenciem o benefício da adição dos inibidores das colinesterases aos antidepressivos no tratamento destes pacientes. Universidade de São Paulo. Faculdade de Medicina. Instituto de Psiquiatria2007-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/acp/article/view/1708410.1590/S0101-60832007000600006Revista de Psiquiatria Clínica; Vol. 34 Núm. 6 (2007); 290-293Archives of Clinical Psychiatry; v. 34 n. 6 (2007); 290-293Archives of Clinical Psychiatry; Vol. 34 No. 6 (2007); 290-2931806-938X0101-6083reponame:Archives of Clinical Psychiatryinstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/acp/article/view/17084/19079Barcelos, RicardoFaria, JulianoGrossi, PauloAparício, Marco Antonio MoscosoBottino, Cássio M. C.info:eu-repo/semantics/openAccess2012-09-26T14:23:08Zoai:revistas.usp.br:article/17084Revistahttp://www.hcnet.usp.br/ipq/revista/index.htmlPUBhttps://old.scielo.br/oai/scielo-oai.php||archives@usp.br1806-938X0101-6083opendoar:2012-09-26T14:23:08Archives of Clinical Psychiatry - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor
Depressão vascular no idoso: resposta ao tratamento antidepressivo associado a inibidor das colinesterases
title Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor
spellingShingle Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor
Barcelos, Ricardo
Vascular depression
vascular dementia
Alzheimer's disease
stroke
neuroimaging
Depressão vascular
demência vascular
doença de Alzheimer
AVC
neuroimagem
title_short Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor
title_full Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor
title_fullStr Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor
title_full_unstemmed Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor
title_sort Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor
author Barcelos, Ricardo
author_facet Barcelos, Ricardo
Faria, Juliano
Grossi, Paulo
Aparício, Marco Antonio Moscoso
Bottino, Cássio M. C.
author_role author
author2 Faria, Juliano
Grossi, Paulo
Aparício, Marco Antonio Moscoso
Bottino, Cássio M. C.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Barcelos, Ricardo
Faria, Juliano
Grossi, Paulo
Aparício, Marco Antonio Moscoso
Bottino, Cássio M. C.
dc.subject.por.fl_str_mv Vascular depression
vascular dementia
Alzheimer's disease
stroke
neuroimaging
Depressão vascular
demência vascular
doença de Alzheimer
AVC
neuroimagem
topic Vascular depression
vascular dementia
Alzheimer's disease
stroke
neuroimaging
Depressão vascular
demência vascular
doença de Alzheimer
AVC
neuroimagem
description CONTEXT: Among neuropsychiatric disorders caused by cerebrovascular factors, vascular depression is diagnosed in a small degree by general practitioners, causing morbid-mortality increase in elderly. CASE REPORT: That is a case of a 67 year-old-man with partial response after treatment with a Selective Serotonin Receptors Inhibitor, and severe autonomic adverse effects with other antidepressants. The addition of rivastigmine to citalopram resulted in a therapeutic success, with a reduction of 23 to 7 points on the Hamilton Depressive Scale (HAM-D). DISCUSSION: The result obtained brings new perspectives to the treatment of vascular depression, providing that randomized controlled trials with larger sample sizes confirm the positive effect of the addition of a cholinesterase inhibitor to antidepressants in the treatment of these patients.
publishDate 2007
dc.date.none.fl_str_mv 2007-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/acp/article/view/17084
10.1590/S0101-60832007000600006
url https://www.revistas.usp.br/acp/article/view/17084
identifier_str_mv 10.1590/S0101-60832007000600006
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/acp/article/view/17084/19079
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina. Instituto de Psiquiatria
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina. Instituto de Psiquiatria
dc.source.none.fl_str_mv Revista de Psiquiatria Clínica; Vol. 34 Núm. 6 (2007); 290-293
Archives of Clinical Psychiatry; v. 34 n. 6 (2007); 290-293
Archives of Clinical Psychiatry; Vol. 34 No. 6 (2007); 290-293
1806-938X
0101-6083
reponame:Archives of Clinical Psychiatry
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Archives of Clinical Psychiatry
collection Archives of Clinical Psychiatry
repository.name.fl_str_mv Archives of Clinical Psychiatry - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||archives@usp.br
_version_ 1787713901940441088

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