Rotor for a transventricular blood pump.
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Tipo de documento: | Dissertação |
Idioma: | eng |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da USP |
Texto Completo: | https://doi.org/10.11606/D.3.2019.tde-21102019-085421 |
Resumo: | According to the World Health Organization, cardiovascular diseases (CVDs) are the number one cause of death worldwide, except in Africa, where Acquired Immunodeficiency Syndrome is the leading cause of death. In this context, the continued development of new devices to assist blood pumping until the transplant, has great value. The Dante Pazzanese Institute of Cardiology (IDPC, São Paulo, Brazil) has recently started a research and development project aiming an axial flow blood pump to be fully implanted within the heart. This pump, called Transventricular Assist Device (TVAD), can be implanted surgically through a small left intercostal incision in a minimally invasive manner. The objective of this research is to develop and analyze the rotor of the TVAD, aiming at the best conditions to support the circulatory system and to achieve: minimum areas of recirculating/stagnating flow and minimum shear stresses. The study is conducted through Computational Fluid Dynamics (CFD) and In Vitro tests. Based on literature, a sort of rotors featuring different geometries and number of blades are defined and tested. The hydrodynamic characteristics of the rotors are compared each other so as to determine the best one. Besides, studies are performed to determine the importance of volute vanes in the TVAD pumping characteristics. Finally, studies are carried out to verify the influence of the gap reduction between the periphery of the blade and the volute on the pumping characteristics as well on the hemolysis. The study showed that the rotor that presented the best performance were the rotor with two blades of constant pitch arranged each other at 180º. Suggesting that, for this device: (I) the higher the blade pitch, the higher the pressure load, the lower flow rate, and increases shear stress; (II) a variable pitch decrease the pump efficiency and (III) a non-continuous blade decreases significantly the pump\'s hydrodynamic performance and decreases the shear stress. At this speed, the maximum manometric head was of 126 mmHg and a maximum flow rate of 4.5 L/min. It is expected to have a low normalized index of hemolysis (NIH). |
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info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis Rotor for a transventricular blood pump. Rotor de uma bomba de sangue transventricular. 2019-08-14Oswaldo HorikawaEduardo Guy Perpétuo BockJose Roberto CardosoGustavo Caravita de AndradeUniversidade de São PauloEngenharia MecânicaUSPBR Axial flow pump Bomba de fluxo axial Computational fluid dynamics Dinâmica dos fluidos Dispositivo de assistência ventricular Estudo fluidodinâmico Impeller Método dos elementos finitos Simulação computacional Transventricular Ventricular assist device Ventrículo cardíaco According to the World Health Organization, cardiovascular diseases (CVDs) are the number one cause of death worldwide, except in Africa, where Acquired Immunodeficiency Syndrome is the leading cause of death. In this context, the continued development of new devices to assist blood pumping until the transplant, has great value. The Dante Pazzanese Institute of Cardiology (IDPC, São Paulo, Brazil) has recently started a research and development project aiming an axial flow blood pump to be fully implanted within the heart. This pump, called Transventricular Assist Device (TVAD), can be implanted surgically through a small left intercostal incision in a minimally invasive manner. The objective of this research is to develop and analyze the rotor of the TVAD, aiming at the best conditions to support the circulatory system and to achieve: minimum areas of recirculating/stagnating flow and minimum shear stresses. The study is conducted through Computational Fluid Dynamics (CFD) and In Vitro tests. Based on literature, a sort of rotors featuring different geometries and number of blades are defined and tested. The hydrodynamic characteristics of the rotors are compared each other so as to determine the best one. Besides, studies are performed to determine the importance of volute vanes in the TVAD pumping characteristics. Finally, studies are carried out to verify the influence of the gap reduction between the periphery of the blade and the volute on the pumping characteristics as well on the hemolysis. The study showed that the rotor that presented the best performance were the rotor with two blades of constant pitch arranged each other at 180º. Suggesting that, for this device: (I) the higher the blade pitch, the higher the pressure load, the lower flow rate, and increases shear stress; (II) a variable pitch decrease the pump efficiency and (III) a non-continuous blade decreases significantly the pump\'s hydrodynamic performance and decreases the shear stress. At this speed, the maximum manometric head was of 126 mmHg and a maximum flow rate of 4.5 L/min. It is expected to have a low normalized index of hemolysis (NIH). Segundo a Organização Mundial de Saúde, as doenças cardiovasculares(DCVs) são a causa número um de mortes em todo o mundo, exceto na África, onde a Síndrome da Imunodeficiência Adquirida é a principal causa de morte. Nesse cenário, o dispositivo de assistência ventricular (DAV) permanece como a única alternativa para prolongar a vida do paciente até o transplante cardíaco. No Instituto Dante Pazzanese de Cardiologia (IDPC), iniciou-se uma pesquisa e desenvolvimento de um DAV de Fluxo axial para ser totalmente implantável dentro do coração. Esta bomba, denominada Dispositivo de Assistência Transventricular (DATV), poderá ser implantada cirurgicamente através de uma pequena incisão intercostal esquerda de maneira minimamente invasiva. O objetivo desta pesquisa é desenvolver e analisar o fuso do DATV visando as melhores condições para auxiliar o funcionamento do sistema circulatório e evitar ao máximo as áreas de Fluxo recirculante, estagnação de Fluxo e elevadas tensões de cisalhamento no fluido por meio de técnicas de Dinâmica dos Fluidos Computacional (CFD) e testes In Vitro. São comparados rotores com diferentes tipos de aletas, eles se diferenciam pela curvatura e quantidade das aletas, baseando-se na literatura. São realizados estudos para determinar a importância de aletas na carcaça do DATV, concluindo que a carcaça com aletas é melhor, proporcionando Pressão e Fluxo maiores em menores rotações. São também realizados estudos sobre a influência da redução do gap entre o topo da aleta e a carcaça, esta redução aumentou a Pressão manométrica, porém houve um aumento significativo na tensão de cisalhamento. Os estudos mostram que o rotor com o melhor desempenho foi o rotor com 2 aletas dispostas a 180º, contínuo (apenas uma coluna de aletas) e com o passo da aleta sendo constante, o rotor 1Rev. Isto sugere que, para este dispositivo: (I) quanto maior o passo da pá, maior a carga de pressão, menor a vazão e aumenta a tensão de cisalhamento; (II) um passo variável diminui a eficiência da bomba e (III) uma lâmina não contínua diminui significativamente o desempenho hidrodinâmico da bomba e diminui a tensão de cisalhamento. Este rotor permitiu ainda atingir, a 12.500 rpm, uma altura manométrica máxima de 126 mmHg e uma vazão máxima de 4,5 L/min. Espera-se um baixo índice normalizado de hemólise (INH). https://doi.org/10.11606/D.3.2019.tde-21102019-085421info:eu-repo/semantics/openAccessengreponame:Biblioteca Digital de Teses e Dissertações da USPinstname:Universidade de São Paulo (USP)instacron:USP2023-12-21T19:49:08Zoai:teses.usp.br:tde-21102019-085421Biblioteca Digital de Teses e Dissertaçõeshttp://www.teses.usp.br/PUBhttp://www.teses.usp.br/cgi-bin/mtd2br.plvirginia@if.usp.br|| atendimento@aguia.usp.br||virginia@if.usp.bropendoar:27212023-12-22T13:06:23.094409Biblioteca Digital de Teses e Dissertações da USP - Universidade de São Paulo (USP)false |
dc.title.en.fl_str_mv |
Rotor for a transventricular blood pump. |
dc.title.alternative.pt.fl_str_mv |
Rotor de uma bomba de sangue transventricular. |
title |
Rotor for a transventricular blood pump. |
spellingShingle |
Rotor for a transventricular blood pump. Gustavo Caravita de Andrade |
title_short |
Rotor for a transventricular blood pump. |
title_full |
Rotor for a transventricular blood pump. |
title_fullStr |
Rotor for a transventricular blood pump. |
title_full_unstemmed |
Rotor for a transventricular blood pump. |
title_sort |
Rotor for a transventricular blood pump. |
author |
Gustavo Caravita de Andrade |
author_facet |
Gustavo Caravita de Andrade |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Oswaldo Horikawa |
dc.contributor.referee1.fl_str_mv |
Eduardo Guy Perpétuo Bock |
dc.contributor.referee2.fl_str_mv |
Jose Roberto Cardoso |
dc.contributor.author.fl_str_mv |
Gustavo Caravita de Andrade |
contributor_str_mv |
Oswaldo Horikawa Eduardo Guy Perpétuo Bock Jose Roberto Cardoso |
description |
According to the World Health Organization, cardiovascular diseases (CVDs) are the number one cause of death worldwide, except in Africa, where Acquired Immunodeficiency Syndrome is the leading cause of death. In this context, the continued development of new devices to assist blood pumping until the transplant, has great value. The Dante Pazzanese Institute of Cardiology (IDPC, São Paulo, Brazil) has recently started a research and development project aiming an axial flow blood pump to be fully implanted within the heart. This pump, called Transventricular Assist Device (TVAD), can be implanted surgically through a small left intercostal incision in a minimally invasive manner. The objective of this research is to develop and analyze the rotor of the TVAD, aiming at the best conditions to support the circulatory system and to achieve: minimum areas of recirculating/stagnating flow and minimum shear stresses. The study is conducted through Computational Fluid Dynamics (CFD) and In Vitro tests. Based on literature, a sort of rotors featuring different geometries and number of blades are defined and tested. The hydrodynamic characteristics of the rotors are compared each other so as to determine the best one. Besides, studies are performed to determine the importance of volute vanes in the TVAD pumping characteristics. Finally, studies are carried out to verify the influence of the gap reduction between the periphery of the blade and the volute on the pumping characteristics as well on the hemolysis. The study showed that the rotor that presented the best performance were the rotor with two blades of constant pitch arranged each other at 180º. Suggesting that, for this device: (I) the higher the blade pitch, the higher the pressure load, the lower flow rate, and increases shear stress; (II) a variable pitch decrease the pump efficiency and (III) a non-continuous blade decreases significantly the pump\'s hydrodynamic performance and decreases the shear stress. At this speed, the maximum manometric head was of 126 mmHg and a maximum flow rate of 4.5 L/min. It is expected to have a low normalized index of hemolysis (NIH). |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019-08-14 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.11606/D.3.2019.tde-21102019-085421 |
url |
https://doi.org/10.11606/D.3.2019.tde-21102019-085421 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo |
dc.publisher.program.fl_str_mv |
Engenharia Mecânica |
dc.publisher.initials.fl_str_mv |
USP |
dc.publisher.country.fl_str_mv |
BR |
publisher.none.fl_str_mv |
Universidade de São Paulo |
dc.source.none.fl_str_mv |
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Universidade de São Paulo (USP) |
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USP |
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Biblioteca Digital de Teses e Dissertações da USP |
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Biblioteca Digital de Teses e Dissertações da USP |
repository.name.fl_str_mv |
Biblioteca Digital de Teses e Dissertações da USP - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
virginia@if.usp.br|| atendimento@aguia.usp.br||virginia@if.usp.br |
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1794502954047242240 |