Leishmanicidal activity of different parts from Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) doi: http://dx.doi.org/10.5892/ruvrv.2012.101.4955

Detalhes bibliográficos
Autor(a) principal: PEREIRA, Ivan Oliveira; UninCor/Unesp/Unifal
Data de Publicação: 2012
Outros Autores: ROCHA, Claudia Quintino, ROSA, Isael Aparecido, MENDONÇA, Alexandre Tourino, VILEGAS, Wagner, SACRAMENTO, Luis Vitor Silva do, MARQUES, Marcos José
Tipo de documento:
Idioma: por
Título da fonte: Revista da Universidade Vale do Rio Verde (Online)
Texto Completo: http://periodicos.unincor.br/index.php/revistaunincor/article/view/504
Resumo: Infections by protozoans of the genus Leishmania are the major worldwide health problem, with high endemicity in developing countries. The drugs of choice for the treatment of leishmaniasis are the pentavalent antimonials, which exert renal and cardiac toxicity. Thus, there is a strong need for safer and more effective treatments against leishmaniasis. The present study was designated to evaluate, by a bioguided assay, the leishmanicidal activity of hidro-ethanolic extracts from different parts (leves, caule and root) of one same plant the Arrabidaea brachypoda (DC.) Bureau. Its has been used to relieve general pain, painful joints and kidney stones in Brazilian folk medicine. Nevertheless, scientific information regarding this species is scarce; there are no reports related to its possible leishmanicidal activity. The leves extract presented the best activity on promastigotes forms of Leishmania (L.) amazonensis, when compared to the other extracts. It showed significant activity on Leishmania (L.) amazonensis. Our results are promising, showing that these compounds are biologically active on Leishmania (L.) amazonensis.
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spelling Leishmanicidal activity of different parts from Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) doi: http://dx.doi.org/10.5892/ruvrv.2012.101.4955ParasitologyArrabidaea brachypoda. Leishmania. PromastigotesNeglected diseasesInfections by protozoans of the genus Leishmania are the major worldwide health problem, with high endemicity in developing countries. The drugs of choice for the treatment of leishmaniasis are the pentavalent antimonials, which exert renal and cardiac toxicity. Thus, there is a strong need for safer and more effective treatments against leishmaniasis. The present study was designated to evaluate, by a bioguided assay, the leishmanicidal activity of hidro-ethanolic extracts from different parts (leves, caule and root) of one same plant the Arrabidaea brachypoda (DC.) Bureau. Its has been used to relieve general pain, painful joints and kidney stones in Brazilian folk medicine. Nevertheless, scientific information regarding this species is scarce; there are no reports related to its possible leishmanicidal activity. The leves extract presented the best activity on promastigotes forms of Leishmania (L.) amazonensis, when compared to the other extracts. It showed significant activity on Leishmania (L.) amazonensis. Our results are promising, showing that these compounds are biologically active on Leishmania (L.) amazonensis.ABECPEREIRA, Ivan Oliveira; UninCor/Unesp/UnifalROCHA, Claudia QuintinoROSA, Isael AparecidoMENDONÇA, Alexandre TourinoVILEGAS, WagnerSACRAMENTO, Luis Vitor Silva doMARQUES, Marcos José2012-07-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://periodicos.unincor.br/index.php/revistaunincor/article/view/50410.5892/504Revista da Universidade Vale do Rio Verde; v. 10, n. 1 (2012); 49-552236-53621517-027610.5892/ruvrd.v10i1reponame:Revista da Universidade Vale do Rio Verde (Online)instname:Universidade Vale do Rio Verde (UNINCOR)instacron:UVRVporhttp://periodicos.unincor.br/index.php/revistaunincor/article/view/504/pdf10.5892/ruvrd.v10i1.504.g473Direitos autorais 2021 Revista da Universidade Vale do Rio Verdeinfo:eu-repo/semantics/openAccess2015-08-24T16:17:51ZRevistahttp://periodicos.unincor.br/index.php/revistaunincor/indexPRI
dc.title.none.fl_str_mv Leishmanicidal activity of different parts from Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) doi: http://dx.doi.org/10.5892/ruvrv.2012.101.4955
title Leishmanicidal activity of different parts from Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) doi: http://dx.doi.org/10.5892/ruvrv.2012.101.4955
spellingShingle Leishmanicidal activity of different parts from Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) doi: http://dx.doi.org/10.5892/ruvrv.2012.101.4955
PEREIRA, Ivan Oliveira; UninCor/Unesp/Unifal
Parasitology
Arrabidaea brachypoda. Leishmania. Promastigotes
Neglected diseases
title_short Leishmanicidal activity of different parts from Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) doi: http://dx.doi.org/10.5892/ruvrv.2012.101.4955
title_full Leishmanicidal activity of different parts from Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) doi: http://dx.doi.org/10.5892/ruvrv.2012.101.4955
title_fullStr Leishmanicidal activity of different parts from Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) doi: http://dx.doi.org/10.5892/ruvrv.2012.101.4955
title_full_unstemmed Leishmanicidal activity of different parts from Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) doi: http://dx.doi.org/10.5892/ruvrv.2012.101.4955
title_sort Leishmanicidal activity of different parts from Arrabidaea brachypoda (DC.) Bureau (Bignoniaceae) doi: http://dx.doi.org/10.5892/ruvrv.2012.101.4955
author PEREIRA, Ivan Oliveira; UninCor/Unesp/Unifal
author_facet PEREIRA, Ivan Oliveira; UninCor/Unesp/Unifal
ROCHA, Claudia Quintino
ROSA, Isael Aparecido
MENDONÇA, Alexandre Tourino
VILEGAS, Wagner
SACRAMENTO, Luis Vitor Silva do
MARQUES, Marcos José
author_role author
author2 ROCHA, Claudia Quintino
ROSA, Isael Aparecido
MENDONÇA, Alexandre Tourino
VILEGAS, Wagner
SACRAMENTO, Luis Vitor Silva do
MARQUES, Marcos José
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.contributor.author.fl_str_mv PEREIRA, Ivan Oliveira; UninCor/Unesp/Unifal
ROCHA, Claudia Quintino
ROSA, Isael Aparecido
MENDONÇA, Alexandre Tourino
VILEGAS, Wagner
SACRAMENTO, Luis Vitor Silva do
MARQUES, Marcos José
dc.subject.por.fl_str_mv Parasitology
Arrabidaea brachypoda. Leishmania. Promastigotes
Neglected diseases
topic Parasitology
Arrabidaea brachypoda. Leishmania. Promastigotes
Neglected diseases
description Infections by protozoans of the genus Leishmania are the major worldwide health problem, with high endemicity in developing countries. The drugs of choice for the treatment of leishmaniasis are the pentavalent antimonials, which exert renal and cardiac toxicity. Thus, there is a strong need for safer and more effective treatments against leishmaniasis. The present study was designated to evaluate, by a bioguided assay, the leishmanicidal activity of hidro-ethanolic extracts from different parts (leves, caule and root) of one same plant the Arrabidaea brachypoda (DC.) Bureau. Its has been used to relieve general pain, painful joints and kidney stones in Brazilian folk medicine. Nevertheless, scientific information regarding this species is scarce; there are no reports related to its possible leishmanicidal activity. The leves extract presented the best activity on promastigotes forms of Leishmania (L.) amazonensis, when compared to the other extracts. It showed significant activity on Leishmania (L.) amazonensis. Our results are promising, showing that these compounds are biologically active on Leishmania (L.) amazonensis.
publishDate 2012
dc.date.none.fl_str_mv 2012-07-23
dc.type.none.fl_str_mv

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dc.relation.none.fl_str_mv http://periodicos.unincor.br/index.php/revistaunincor/article/view/504/pdf
10.5892/ruvrd.v10i1.504.g473
dc.rights.driver.fl_str_mv Direitos autorais 2021 Revista da Universidade Vale do Rio Verde
info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv ABEC
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dc.source.none.fl_str_mv Revista da Universidade Vale do Rio Verde; v. 10, n. 1 (2012); 49-55
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10.5892/ruvrd.v10i1
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