PHARMACOLOGICAL ANALYSIS OF TWO ETHANOLIC EXTRACTS FROM SPECIES OF FRIDERICIA GENUSDOI: http://dx.doi.org/10.5892/ruvrd.v15i2.3291
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista da Universidade Vale do Rio Verde (Online) |
Texto Completo: | http://periodicos.unincor.br/index.php/revistaunincor/article/view/3291 |
Resumo: | The present study aimed to evaluate the biological activity of the species Fridericia platyphylla e Fridericia florida, through pharmacological tests. The doses of FpEE and FfEE (20 and 100 mg/kg) were used to assess anti-inflammatory activity (carrageenan-induced mice paw edema and formalin test) and analgesic activity (acetic acid-induced writhing and hot plate) by both extracts. In the carrageenan-induced paw edema the highest activity was observed by the FfEE at dose of 20 mg/kg in the third hour (26.63%), followed by FpEE (23.42%) at same dose in the first hour. In the acetic acid-induced writhing, the highest activity was observed by both doses of FpEE, while in hot plate test, FfEE has more pronounced activity than FpEE in times 60 and 90 minutes by both doses. In formalin test, only FfEE was significant at neurogenic pain phase inhibiting the licking time by 29.58%, whereas, FpEE has the highest activity at inflammatory pain phase (84.67%). This study showed that ethanolic extract of F. platyphylla and F. florida plants induced anti-inflammatory and analgesic effect in different tests carried out with Swiss mice albine. |
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PHARMACOLOGICAL ANALYSIS OF TWO ETHANOLIC EXTRACTS FROM SPECIES OF FRIDERICIA GENUSDOI: http://dx.doi.org/10.5892/ruvrd.v15i2.3291Farmacologia; Produtos Naturais;Medicinal plants; Anti-inflammatory; Analgesic; Fridericia;Extratos vegetais; Inflamação; Dor; CamundongosThe present study aimed to evaluate the biological activity of the species Fridericia platyphylla e Fridericia florida, through pharmacological tests. The doses of FpEE and FfEE (20 and 100 mg/kg) were used to assess anti-inflammatory activity (carrageenan-induced mice paw edema and formalin test) and analgesic activity (acetic acid-induced writhing and hot plate) by both extracts. In the carrageenan-induced paw edema the highest activity was observed by the FfEE at dose of 20 mg/kg in the third hour (26.63%), followed by FpEE (23.42%) at same dose in the first hour. In the acetic acid-induced writhing, the highest activity was observed by both doses of FpEE, while in hot plate test, FfEE has more pronounced activity than FpEE in times 60 and 90 minutes by both doses. In formalin test, only FfEE was significant at neurogenic pain phase inhibiting the licking time by 29.58%, whereas, FpEE has the highest activity at inflammatory pain phase (84.67%). This study showed that ethanolic extract of F. platyphylla and F. florida plants induced anti-inflammatory and analgesic effect in different tests carried out with Swiss mice albine.ABECCNPqPinheiro MOURÃO, Pedro Junior; Federal University of AcreMACEDO, Jussara Alice BelezaSILVA, Ana Paula Azevedo Barros daSILVA, Caroline Nunes daMARQUES, Délcio DiasCUNHA, Renildo Moura da2017-08-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://periodicos.unincor.br/index.php/revistaunincor/article/view/329110.5892/ruvrd.v15i2.3291Revista da Universidade Vale do Rio Verde; v. 15, n. 2 (2017); 122-1312236-53621517-027610.5892/ruvrd.v15i2reponame:Revista da Universidade Vale do Rio Verde (Online)instname:Universidade Vale do Rio Verde (UNINCOR)instacron:UVRVporhttp://periodicos.unincor.br/index.php/revistaunincor/article/view/3291/pdf_68610.5892/ruvrd.v15i2.3291.g3218Direitos autorais 2021 Revista da Universidade Vale do Rio Verdeinfo:eu-repo/semantics/openAccess2018-01-09T18:42:43Zoai:ojs.teste.unincor.br:article/3291Revistahttp://periodicos.unincor.br/index.php/revistaunincor/indexPRIhttp://periodicos.unincor.br/index.php/revistaunincor/oairevistaunincor@unincor.edu.br2236-53621517-0276opendoar:2022-05-31T14:30:05.894515Revista da Universidade Vale do Rio Verde (Online) - Universidade Vale do Rio Verde (UNINCOR)false |
dc.title.none.fl_str_mv |
PHARMACOLOGICAL ANALYSIS OF TWO ETHANOLIC EXTRACTS FROM SPECIES OF FRIDERICIA GENUSDOI: http://dx.doi.org/10.5892/ruvrd.v15i2.3291 |
title |
PHARMACOLOGICAL ANALYSIS OF TWO ETHANOLIC EXTRACTS FROM SPECIES OF FRIDERICIA GENUSDOI: http://dx.doi.org/10.5892/ruvrd.v15i2.3291 |
spellingShingle |
PHARMACOLOGICAL ANALYSIS OF TWO ETHANOLIC EXTRACTS FROM SPECIES OF FRIDERICIA GENUSDOI: http://dx.doi.org/10.5892/ruvrd.v15i2.3291 Pinheiro MOURÃO, Pedro Junior; Federal University of Acre Farmacologia; Produtos Naturais; Medicinal plants; Anti-inflammatory; Analgesic; Fridericia; Extratos vegetais; Inflamação; Dor; Camundongos |
title_short |
PHARMACOLOGICAL ANALYSIS OF TWO ETHANOLIC EXTRACTS FROM SPECIES OF FRIDERICIA GENUSDOI: http://dx.doi.org/10.5892/ruvrd.v15i2.3291 |
title_full |
PHARMACOLOGICAL ANALYSIS OF TWO ETHANOLIC EXTRACTS FROM SPECIES OF FRIDERICIA GENUSDOI: http://dx.doi.org/10.5892/ruvrd.v15i2.3291 |
title_fullStr |
PHARMACOLOGICAL ANALYSIS OF TWO ETHANOLIC EXTRACTS FROM SPECIES OF FRIDERICIA GENUSDOI: http://dx.doi.org/10.5892/ruvrd.v15i2.3291 |
title_full_unstemmed |
PHARMACOLOGICAL ANALYSIS OF TWO ETHANOLIC EXTRACTS FROM SPECIES OF FRIDERICIA GENUSDOI: http://dx.doi.org/10.5892/ruvrd.v15i2.3291 |
title_sort |
PHARMACOLOGICAL ANALYSIS OF TWO ETHANOLIC EXTRACTS FROM SPECIES OF FRIDERICIA GENUSDOI: http://dx.doi.org/10.5892/ruvrd.v15i2.3291 |
author |
Pinheiro MOURÃO, Pedro Junior; Federal University of Acre |
author_facet |
Pinheiro MOURÃO, Pedro Junior; Federal University of Acre MACEDO, Jussara Alice Beleza SILVA, Ana Paula Azevedo Barros da SILVA, Caroline Nunes da MARQUES, Délcio Dias CUNHA, Renildo Moura da |
author_role |
author |
author2 |
MACEDO, Jussara Alice Beleza SILVA, Ana Paula Azevedo Barros da SILVA, Caroline Nunes da MARQUES, Délcio Dias CUNHA, Renildo Moura da |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
CNPq |
dc.contributor.author.fl_str_mv |
Pinheiro MOURÃO, Pedro Junior; Federal University of Acre MACEDO, Jussara Alice Beleza SILVA, Ana Paula Azevedo Barros da SILVA, Caroline Nunes da MARQUES, Délcio Dias CUNHA, Renildo Moura da |
dc.subject.por.fl_str_mv |
Farmacologia; Produtos Naturais; Medicinal plants; Anti-inflammatory; Analgesic; Fridericia; Extratos vegetais; Inflamação; Dor; Camundongos |
topic |
Farmacologia; Produtos Naturais; Medicinal plants; Anti-inflammatory; Analgesic; Fridericia; Extratos vegetais; Inflamação; Dor; Camundongos |
description |
The present study aimed to evaluate the biological activity of the species Fridericia platyphylla e Fridericia florida, through pharmacological tests. The doses of FpEE and FfEE (20 and 100 mg/kg) were used to assess anti-inflammatory activity (carrageenan-induced mice paw edema and formalin test) and analgesic activity (acetic acid-induced writhing and hot plate) by both extracts. In the carrageenan-induced paw edema the highest activity was observed by the FfEE at dose of 20 mg/kg in the third hour (26.63%), followed by FpEE (23.42%) at same dose in the first hour. In the acetic acid-induced writhing, the highest activity was observed by both doses of FpEE, while in hot plate test, FfEE has more pronounced activity than FpEE in times 60 and 90 minutes by both doses. In formalin test, only FfEE was significant at neurogenic pain phase inhibiting the licking time by 29.58%, whereas, FpEE has the highest activity at inflammatory pain phase (84.67%). This study showed that ethanolic extract of F. platyphylla and F. florida plants induced anti-inflammatory and analgesic effect in different tests carried out with Swiss mice albine. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-08-27 |
dc.type.none.fl_str_mv |
|
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://periodicos.unincor.br/index.php/revistaunincor/article/view/3291 10.5892/ruvrd.v15i2.3291 |
url |
http://periodicos.unincor.br/index.php/revistaunincor/article/view/3291 |
identifier_str_mv |
10.5892/ruvrd.v15i2.3291 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
http://periodicos.unincor.br/index.php/revistaunincor/article/view/3291/pdf_686 10.5892/ruvrd.v15i2.3291.g3218 |
dc.rights.driver.fl_str_mv |
Direitos autorais 2021 Revista da Universidade Vale do Rio Verde info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos autorais 2021 Revista da Universidade Vale do Rio Verde |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.coverage.none.fl_str_mv |
|
dc.publisher.none.fl_str_mv |
ABEC |
publisher.none.fl_str_mv |
ABEC |
dc.source.none.fl_str_mv |
Revista da Universidade Vale do Rio Verde; v. 15, n. 2 (2017); 122-131 2236-5362 1517-0276 10.5892/ruvrd.v15i2 reponame:Revista da Universidade Vale do Rio Verde (Online) instname:Universidade Vale do Rio Verde (UNINCOR) instacron:UVRV |
instname_str |
Universidade Vale do Rio Verde (UNINCOR) |
instacron_str |
UVRV |
institution |
UVRV |
reponame_str |
Revista da Universidade Vale do Rio Verde (Online) |
collection |
Revista da Universidade Vale do Rio Verde (Online) |
repository.name.fl_str_mv |
Revista da Universidade Vale do Rio Verde (Online) - Universidade Vale do Rio Verde (UNINCOR) |
repository.mail.fl_str_mv |
revistaunincor@unincor.edu.br |
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1797051198075830272 |