Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Medical and Biological Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700011 |
Resumo: | Caffeine is the most consumed psychoactive substance in the world. The effects of caffeine have been studied using cognitive and motor measures, quantitative electroencephalography (qEEG) and event-related potentials. However, these methods are not usually employed in combination, a fact that impairs the interpretation of the results. The objective of the present study was to analyze changes in electrophysiological, cognitive and motor variables with the ingestion of caffeine, and to relate central to peripheral responses. For this purpose we recorded event-related potentials and eyes-closed, resting EEG, applied the Stroop test, and measured reaction time. Fifteen volunteers took caffeine (400 mg) or placebo in a randomized, crossover, double-blind design. A significant reduction of alpha absolute power over the entire scalp and of P300 latency at the Fz electrode were observed after caffeine ingestion. These results are consistent with a stimulatory effect of caffeine, although there was no change in the attention (Stroop) test or in reaction time. The qEEG seems to be the most sensitive index of the changes produced by caffeine in the central nervous system since it proved to be capable of detecting changes that were not evident in the tests of cognitive or motor performance. |
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Brazilian Journal of Medical and Biological Research |
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Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous systemQuantitative electroencephalographyP300CaffeineCognitive and motor measuresPsychostimulantsCaffeine is the most consumed psychoactive substance in the world. The effects of caffeine have been studied using cognitive and motor measures, quantitative electroencephalography (qEEG) and event-related potentials. However, these methods are not usually employed in combination, a fact that impairs the interpretation of the results. The objective of the present study was to analyze changes in electrophysiological, cognitive and motor variables with the ingestion of caffeine, and to relate central to peripheral responses. For this purpose we recorded event-related potentials and eyes-closed, resting EEG, applied the Stroop test, and measured reaction time. Fifteen volunteers took caffeine (400 mg) or placebo in a randomized, crossover, double-blind design. A significant reduction of alpha absolute power over the entire scalp and of P300 latency at the Fz electrode were observed after caffeine ingestion. These results are consistent with a stimulatory effect of caffeine, although there was no change in the attention (Stroop) test or in reaction time. The qEEG seems to be the most sensitive index of the changes produced by caffeine in the central nervous system since it proved to be capable of detecting changes that were not evident in the tests of cognitive or motor performance.Associação Brasileira de Divulgação Científica2005-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700011Brazilian Journal of Medical and Biological Research v.38 n.7 2005reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2005000700011info:eu-repo/semantics/openAccessDeslandes,A.C.Veiga,H.Cagy,M.Piedade,R.Pompeu,F.Ribeiro,P.eng2005-07-04T00:00:00Zoai:scielo:S0100-879X2005000700011Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2005-07-04T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false |
dc.title.none.fl_str_mv |
Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system |
title |
Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system |
spellingShingle |
Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system Deslandes,A.C. Quantitative electroencephalography P300 Caffeine Cognitive and motor measures Psychostimulants |
title_short |
Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system |
title_full |
Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system |
title_fullStr |
Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system |
title_full_unstemmed |
Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system |
title_sort |
Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system |
author |
Deslandes,A.C. |
author_facet |
Deslandes,A.C. Veiga,H. Cagy,M. Piedade,R. Pompeu,F. Ribeiro,P. |
author_role |
author |
author2 |
Veiga,H. Cagy,M. Piedade,R. Pompeu,F. Ribeiro,P. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Deslandes,A.C. Veiga,H. Cagy,M. Piedade,R. Pompeu,F. Ribeiro,P. |
dc.subject.por.fl_str_mv |
Quantitative electroencephalography P300 Caffeine Cognitive and motor measures Psychostimulants |
topic |
Quantitative electroencephalography P300 Caffeine Cognitive and motor measures Psychostimulants |
description |
Caffeine is the most consumed psychoactive substance in the world. The effects of caffeine have been studied using cognitive and motor measures, quantitative electroencephalography (qEEG) and event-related potentials. However, these methods are not usually employed in combination, a fact that impairs the interpretation of the results. The objective of the present study was to analyze changes in electrophysiological, cognitive and motor variables with the ingestion of caffeine, and to relate central to peripheral responses. For this purpose we recorded event-related potentials and eyes-closed, resting EEG, applied the Stroop test, and measured reaction time. Fifteen volunteers took caffeine (400 mg) or placebo in a randomized, crossover, double-blind design. A significant reduction of alpha absolute power over the entire scalp and of P300 latency at the Fz electrode were observed after caffeine ingestion. These results are consistent with a stimulatory effect of caffeine, although there was no change in the attention (Stroop) test or in reaction time. The qEEG seems to be the most sensitive index of the changes produced by caffeine in the central nervous system since it proved to be capable of detecting changes that were not evident in the tests of cognitive or motor performance. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-879X2005000700011 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research v.38 n.7 2005 reponame:Brazilian Journal of Medical and Biological Research instname:Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC |
instname_str |
Associação Brasileira de Divulgação Científica (ABDC) |
instacron_str |
ABDC |
institution |
ABDC |
reponame_str |
Brazilian Journal of Medical and Biological Research |
collection |
Brazilian Journal of Medical and Biological Research |
repository.name.fl_str_mv |
Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC) |
repository.mail.fl_str_mv |
bjournal@terra.com.br||bjournal@terra.com.br |
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1754302933876342784 |