Presence of t(14;18) translocation in healthy individuals varies according to ethnic background in the Brazilian population

Detalhes bibliográficos
Autor(a) principal: Levy,D.
Data de Publicação: 2017
Outros Autores: Bertoldi,E.R.M., Ruiz,J.L.M., Pereira,J., Bydlowski,S.P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Medical and Biological Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000700602
Resumo: Several groups have demonstrated that healthy individuals can present the t(14;18) translocation. In this report, the presence of the translocation was examined in healthy blood donors in Brazil, a country considered an ethnic melting pot. The translocation was detected by nested PCR in 227 peripheral blood samples from individuals with different ethnic backgrounds. The t(14;18) translocation was found in 45 of 85 White individuals (52.94%); in 57 of 72 Black individuals (79.17%); and in 68 of 70 individuals (97.14%) of Japanese-descent. In conclusion, the frequency of the t(14;18) translocation in the Brazilian population varies according to the ethnic background.
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spelling Presence of t(14;18) translocation in healthy individuals varies according to ethnic background in the Brazilian populationt(14;18)LymphomasCharacterizationMolecular geneticsSeveral groups have demonstrated that healthy individuals can present the t(14;18) translocation. In this report, the presence of the translocation was examined in healthy blood donors in Brazil, a country considered an ethnic melting pot. The translocation was detected by nested PCR in 227 peripheral blood samples from individuals with different ethnic backgrounds. The t(14;18) translocation was found in 45 of 85 White individuals (52.94%); in 57 of 72 Black individuals (79.17%); and in 68 of 70 individuals (97.14%) of Japanese-descent. In conclusion, the frequency of the t(14;18) translocation in the Brazilian population varies according to the ethnic background.Associação Brasileira de Divulgação Científica2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000700602Brazilian Journal of Medical and Biological Research v.50 n.7 2017reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/1414-431x20176172info:eu-repo/semantics/openAccessLevy,D.Bertoldi,E.R.M.Ruiz,J.L.M.Pereira,J.Bydlowski,S.P.eng2019-03-19T00:00:00Zoai:scielo:S0100-879X2017000700602Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2019-03-19T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false
dc.title.none.fl_str_mv Presence of t(14;18) translocation in healthy individuals varies according to ethnic background in the Brazilian population
title Presence of t(14;18) translocation in healthy individuals varies according to ethnic background in the Brazilian population
spellingShingle Presence of t(14;18) translocation in healthy individuals varies according to ethnic background in the Brazilian population
Levy,D.
t(14;18)
Lymphomas
Characterization
Molecular genetics
title_short Presence of t(14;18) translocation in healthy individuals varies according to ethnic background in the Brazilian population
title_full Presence of t(14;18) translocation in healthy individuals varies according to ethnic background in the Brazilian population
title_fullStr Presence of t(14;18) translocation in healthy individuals varies according to ethnic background in the Brazilian population
title_full_unstemmed Presence of t(14;18) translocation in healthy individuals varies according to ethnic background in the Brazilian population
title_sort Presence of t(14;18) translocation in healthy individuals varies according to ethnic background in the Brazilian population
author Levy,D.
author_facet Levy,D.
Bertoldi,E.R.M.
Ruiz,J.L.M.
Pereira,J.
Bydlowski,S.P.
author_role author
author2 Bertoldi,E.R.M.
Ruiz,J.L.M.
Pereira,J.
Bydlowski,S.P.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Levy,D.
Bertoldi,E.R.M.
Ruiz,J.L.M.
Pereira,J.
Bydlowski,S.P.
dc.subject.por.fl_str_mv t(14;18)
Lymphomas
Characterization
Molecular genetics
topic t(14;18)
Lymphomas
Characterization
Molecular genetics
description Several groups have demonstrated that healthy individuals can present the t(14;18) translocation. In this report, the presence of the translocation was examined in healthy blood donors in Brazil, a country considered an ethnic melting pot. The translocation was detected by nested PCR in 227 peripheral blood samples from individuals with different ethnic backgrounds. The t(14;18) translocation was found in 45 of 85 White individuals (52.94%); in 57 of 72 Black individuals (79.17%); and in 68 of 70 individuals (97.14%) of Japanese-descent. In conclusion, the frequency of the t(14;18) translocation in the Brazilian population varies according to the ethnic background.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000700602
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000700602
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1414-431x20176172
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv Brazilian Journal of Medical and Biological Research v.50 n.7 2017
reponame:Brazilian Journal of Medical and Biological Research
instname:Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
instname_str Associação Brasileira de Divulgação Científica (ABDC)
instacron_str ABDC
institution ABDC
reponame_str Brazilian Journal of Medical and Biological Research
collection Brazilian Journal of Medical and Biological Research
repository.name.fl_str_mv Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)
repository.mail.fl_str_mv bjournal@terra.com.br||bjournal@terra.com.br
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