AnaBioPlus: a new package for parameter estimation and simulation of bioprocesses
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Chemical Engineering |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322017000401065 |
Resumo: | Abstract A very important step in the study of bioprocesses is the modeling and simulation of bioreactors. This paper presents the AnaBioPlus software package, which was developed for teaching and research purposes concerning the analysis of bioreactors. The package consists of two programs: OptimusFerm and SimulaFerm. OptimusFerm allows the analysis of experimental batch cultivation data sets in order to estimate parameters of kinetic models by means of a differential evolution method. SimulaFerm performs simulations obtaining values of cell growth, product formation, and limiting substrate consumption for batch, fed-batch and continuous cultivations. Thirty-two kinetic models of cell growth are available in OptimusFerm and SimulaFerm. Two case studies are described in order to illustrate the use of AnaBioPlus. The results show that AnaBioPlus is a very useful tool for the analysis of bioprocesses. Furthermore, it presents a user-friendly graphical interface and is freely available to users, in both English and Portuguese versions. |
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Brazilian Journal of Chemical Engineering |
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AnaBioPlus: a new package for parameter estimation and simulation of bioprocessesFree software, bioprocesskinetic modelingparameter estimationsimulationAbstract A very important step in the study of bioprocesses is the modeling and simulation of bioreactors. This paper presents the AnaBioPlus software package, which was developed for teaching and research purposes concerning the analysis of bioreactors. The package consists of two programs: OptimusFerm and SimulaFerm. OptimusFerm allows the analysis of experimental batch cultivation data sets in order to estimate parameters of kinetic models by means of a differential evolution method. SimulaFerm performs simulations obtaining values of cell growth, product formation, and limiting substrate consumption for batch, fed-batch and continuous cultivations. Thirty-two kinetic models of cell growth are available in OptimusFerm and SimulaFerm. Two case studies are described in order to illustrate the use of AnaBioPlus. The results show that AnaBioPlus is a very useful tool for the analysis of bioprocesses. Furthermore, it presents a user-friendly graphical interface and is freely available to users, in both English and Portuguese versions.Brazilian Society of Chemical Engineering2017-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322017000401065Brazilian Journal of Chemical Engineering v.34 n.4 2017reponame:Brazilian Journal of Chemical Engineeringinstname:Associação Brasileira de Engenharia Química (ABEQ)instacron:ABEQ10.1590/0104-6632.20170344s20150673info:eu-repo/semantics/openAccessOliveira,C. M.Jesus,C. D. F.Ceneviva,L. V. S.Silva,F. H.Cruz,A. J. G.Costa,C. B. B.Badino,A. C.eng2018-04-18T00:00:00Zoai:scielo:S0104-66322017000401065Revistahttps://www.scielo.br/j/bjce/https://old.scielo.br/oai/scielo-oai.phprgiudici@usp.br||rgiudici@usp.br1678-43830104-6632opendoar:2018-04-18T00:00Brazilian Journal of Chemical Engineering - Associação Brasileira de Engenharia Química (ABEQ)false |
dc.title.none.fl_str_mv |
AnaBioPlus: a new package for parameter estimation and simulation of bioprocesses |
title |
AnaBioPlus: a new package for parameter estimation and simulation of bioprocesses |
spellingShingle |
AnaBioPlus: a new package for parameter estimation and simulation of bioprocesses Oliveira,C. M. Free software, bioprocess kinetic modeling parameter estimation simulation |
title_short |
AnaBioPlus: a new package for parameter estimation and simulation of bioprocesses |
title_full |
AnaBioPlus: a new package for parameter estimation and simulation of bioprocesses |
title_fullStr |
AnaBioPlus: a new package for parameter estimation and simulation of bioprocesses |
title_full_unstemmed |
AnaBioPlus: a new package for parameter estimation and simulation of bioprocesses |
title_sort |
AnaBioPlus: a new package for parameter estimation and simulation of bioprocesses |
author |
Oliveira,C. M. |
author_facet |
Oliveira,C. M. Jesus,C. D. F. Ceneviva,L. V. S. Silva,F. H. Cruz,A. J. G. Costa,C. B. B. Badino,A. C. |
author_role |
author |
author2 |
Jesus,C. D. F. Ceneviva,L. V. S. Silva,F. H. Cruz,A. J. G. Costa,C. B. B. Badino,A. C. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira,C. M. Jesus,C. D. F. Ceneviva,L. V. S. Silva,F. H. Cruz,A. J. G. Costa,C. B. B. Badino,A. C. |
dc.subject.por.fl_str_mv |
Free software, bioprocess kinetic modeling parameter estimation simulation |
topic |
Free software, bioprocess kinetic modeling parameter estimation simulation |
description |
Abstract A very important step in the study of bioprocesses is the modeling and simulation of bioreactors. This paper presents the AnaBioPlus software package, which was developed for teaching and research purposes concerning the analysis of bioreactors. The package consists of two programs: OptimusFerm and SimulaFerm. OptimusFerm allows the analysis of experimental batch cultivation data sets in order to estimate parameters of kinetic models by means of a differential evolution method. SimulaFerm performs simulations obtaining values of cell growth, product formation, and limiting substrate consumption for batch, fed-batch and continuous cultivations. Thirty-two kinetic models of cell growth are available in OptimusFerm and SimulaFerm. Two case studies are described in order to illustrate the use of AnaBioPlus. The results show that AnaBioPlus is a very useful tool for the analysis of bioprocesses. Furthermore, it presents a user-friendly graphical interface and is freely available to users, in both English and Portuguese versions. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322017000401065 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322017000401065 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0104-6632.20170344s20150673 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Brazilian Society of Chemical Engineering |
publisher.none.fl_str_mv |
Brazilian Society of Chemical Engineering |
dc.source.none.fl_str_mv |
Brazilian Journal of Chemical Engineering v.34 n.4 2017 reponame:Brazilian Journal of Chemical Engineering instname:Associação Brasileira de Engenharia Química (ABEQ) instacron:ABEQ |
instname_str |
Associação Brasileira de Engenharia Química (ABEQ) |
instacron_str |
ABEQ |
institution |
ABEQ |
reponame_str |
Brazilian Journal of Chemical Engineering |
collection |
Brazilian Journal of Chemical Engineering |
repository.name.fl_str_mv |
Brazilian Journal of Chemical Engineering - Associação Brasileira de Engenharia Química (ABEQ) |
repository.mail.fl_str_mv |
rgiudici@usp.br||rgiudici@usp.br |
_version_ |
1754213175827365888 |