Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000500025 |
Resumo: | Pilocytic astrocytoma (PA) is a benign tumor that rarely spread along the neuraxis. At the moment there are no more than five cases of leptomeningeal dissemination (LD) from PA at diagnosis described in the literature. Different patterns of presentation or recurrence may be noted: local recurrence, malignant transformation, multicentric disease or metastatic disease. LD and multicentric disease can be distinct pathological entities. We report two cases and analyse literature, emphasizing leptomeningeal spread at presentation. Hydrocephalus, biopsy and parcial ressection are likely to be favorable factors to the occurrence of LD. Otherwise, LD may be part of natural history of PA, as evidenced by its ocurrence in non-treated cases. |
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Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases reportpilocytic astrocytomaleptomeningeal disseminationmulticentric diseasecerebrospinal fluidmetastasisradiation therapychemotherapyhydrocephalusPilocytic astrocytoma (PA) is a benign tumor that rarely spread along the neuraxis. At the moment there are no more than five cases of leptomeningeal dissemination (LD) from PA at diagnosis described in the literature. Different patterns of presentation or recurrence may be noted: local recurrence, malignant transformation, multicentric disease or metastatic disease. LD and multicentric disease can be distinct pathological entities. We report two cases and analyse literature, emphasizing leptomeningeal spread at presentation. Hydrocephalus, biopsy and parcial ressection are likely to be favorable factors to the occurrence of LD. Otherwise, LD may be part of natural history of PA, as evidenced by its ocurrence in non-treated cases.Academia Brasileira de Neurologia - ABNEURO2003-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000500025Arquivos de Neuro-Psiquiatria v.61 n.3B 2003reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2003000500025info:eu-repo/semantics/openAccessFigueiredo,Eberval GadelhaMatushita,HamiltonMachado,André Guelman G.Plese,José Píndaro P.Rosemberg,SérgioMarino Jr,Rauleng2003-11-12T00:00:00Zoai:scielo:S0004-282X2003000500025Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2003-11-12T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report |
title |
Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report |
spellingShingle |
Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report Figueiredo,Eberval Gadelha pilocytic astrocytoma leptomeningeal dissemination multicentric disease cerebrospinal fluid metastasis radiation therapy chemotherapy hydrocephalus |
title_short |
Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report |
title_full |
Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report |
title_fullStr |
Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report |
title_full_unstemmed |
Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report |
title_sort |
Leptomeningeal dissemination of pilocytic astrocytoma at diagnosis in childhood: two cases report |
author |
Figueiredo,Eberval Gadelha |
author_facet |
Figueiredo,Eberval Gadelha Matushita,Hamilton Machado,André Guelman G. Plese,José Píndaro P. Rosemberg,Sérgio Marino Jr,Raul |
author_role |
author |
author2 |
Matushita,Hamilton Machado,André Guelman G. Plese,José Píndaro P. Rosemberg,Sérgio Marino Jr,Raul |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Figueiredo,Eberval Gadelha Matushita,Hamilton Machado,André Guelman G. Plese,José Píndaro P. Rosemberg,Sérgio Marino Jr,Raul |
dc.subject.por.fl_str_mv |
pilocytic astrocytoma leptomeningeal dissemination multicentric disease cerebrospinal fluid metastasis radiation therapy chemotherapy hydrocephalus |
topic |
pilocytic astrocytoma leptomeningeal dissemination multicentric disease cerebrospinal fluid metastasis radiation therapy chemotherapy hydrocephalus |
description |
Pilocytic astrocytoma (PA) is a benign tumor that rarely spread along the neuraxis. At the moment there are no more than five cases of leptomeningeal dissemination (LD) from PA at diagnosis described in the literature. Different patterns of presentation or recurrence may be noted: local recurrence, malignant transformation, multicentric disease or metastatic disease. LD and multicentric disease can be distinct pathological entities. We report two cases and analyse literature, emphasizing leptomeningeal spread at presentation. Hydrocephalus, biopsy and parcial ressection are likely to be favorable factors to the occurrence of LD. Otherwise, LD may be part of natural history of PA, as evidenced by its ocurrence in non-treated cases. |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000500025 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000500025 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2003000500025 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.61 n.3B 2003 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
_version_ |
1754212756092878848 |