Beneficial effects of botulinum toxin type A in trigeminal neuralgia

Detalhes bibliográficos
Autor(a) principal: Zúñiga,Carlos
Data de Publicação: 2008
Outros Autores: Díaz,Sergio, Piedimonte,Fabián, Micheli,Federico
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de neuro-psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000400012
Resumo: Botulinum toxin has been thoroughly studied as a potential tool in the treatment of several pain syndromes. Therefore, we assessed the clinical effects of botulinum toxin type A injections in 12 patients with otherwise unresponsive idiopathic trigeminal neuralgia. Patients were infiltrated with 20-50 units of botulinum toxin in trigger zones. Those who presented with mandibular involvement were also infiltrated in the masseter muscle. The patients were assessed on a weekly basis using the Visual Analogic Scale for pain. Ten of our patients reported a significant benefit from botulinum toxin injections, with reduction or even disappearance of pain, and remained pain free for as long as 60 days. Our findings suggest that botulinum toxin may represent a useful therapeutic tool in the management of patients with this entity.
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spelling Beneficial effects of botulinum toxin type A in trigeminal neuralgiatrigeminal neuralgiabotulinum toxinfacial painBotulinum toxin has been thoroughly studied as a potential tool in the treatment of several pain syndromes. Therefore, we assessed the clinical effects of botulinum toxin type A injections in 12 patients with otherwise unresponsive idiopathic trigeminal neuralgia. Patients were infiltrated with 20-50 units of botulinum toxin in trigger zones. Those who presented with mandibular involvement were also infiltrated in the masseter muscle. The patients were assessed on a weekly basis using the Visual Analogic Scale for pain. Ten of our patients reported a significant benefit from botulinum toxin injections, with reduction or even disappearance of pain, and remained pain free for as long as 60 days. Our findings suggest that botulinum toxin may represent a useful therapeutic tool in the management of patients with this entity.Academia Brasileira de Neurologia - ABNEURO2008-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000400012Arquivos de Neuro-Psiquiatria v.66 n.3a 2008reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2008000400012info:eu-repo/semantics/openAccessZúñiga,CarlosDíaz,SergioPiedimonte,FabiánMicheli,Federicoeng2008-09-10T00:00:00Zoai:scielo:S0004-282X2008000400012Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2008-09-10T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse
dc.title.none.fl_str_mv Beneficial effects of botulinum toxin type A in trigeminal neuralgia
title Beneficial effects of botulinum toxin type A in trigeminal neuralgia
spellingShingle Beneficial effects of botulinum toxin type A in trigeminal neuralgia
Zúñiga,Carlos
trigeminal neuralgia
botulinum toxin
facial pain
title_short Beneficial effects of botulinum toxin type A in trigeminal neuralgia
title_full Beneficial effects of botulinum toxin type A in trigeminal neuralgia
title_fullStr Beneficial effects of botulinum toxin type A in trigeminal neuralgia
title_full_unstemmed Beneficial effects of botulinum toxin type A in trigeminal neuralgia
title_sort Beneficial effects of botulinum toxin type A in trigeminal neuralgia
author Zúñiga,Carlos
author_facet Zúñiga,Carlos
Díaz,Sergio
Piedimonte,Fabián
Micheli,Federico
author_role author
author2 Díaz,Sergio
Piedimonte,Fabián
Micheli,Federico
author2_role author
author
author
dc.contributor.author.fl_str_mv Zúñiga,Carlos
Díaz,Sergio
Piedimonte,Fabián
Micheli,Federico
dc.subject.por.fl_str_mv trigeminal neuralgia
botulinum toxin
facial pain
topic trigeminal neuralgia
botulinum toxin
facial pain
description Botulinum toxin has been thoroughly studied as a potential tool in the treatment of several pain syndromes. Therefore, we assessed the clinical effects of botulinum toxin type A injections in 12 patients with otherwise unresponsive idiopathic trigeminal neuralgia. Patients were infiltrated with 20-50 units of botulinum toxin in trigger zones. Those who presented with mandibular involvement were also infiltrated in the masseter muscle. The patients were assessed on a weekly basis using the Visual Analogic Scale for pain. Ten of our patients reported a significant benefit from botulinum toxin injections, with reduction or even disappearance of pain, and remained pain free for as long as 60 days. Our findings suggest that botulinum toxin may represent a useful therapeutic tool in the management of patients with this entity.
publishDate 2008
dc.date.none.fl_str_mv 2008-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000400012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2008000400012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-282X2008000400012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv Arquivos de Neuro-Psiquiatria v.66 n.3a 2008
reponame:Arquivos de neuro-psiquiatria (Online)
instname:Academia Brasileira de Neurologia
instacron:ABNEURO
instname_str Academia Brasileira de Neurologia
instacron_str ABNEURO
institution ABNEURO
reponame_str Arquivos de neuro-psiquiatria (Online)
collection Arquivos de neuro-psiquiatria (Online)
repository.name.fl_str_mv Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia
repository.mail.fl_str_mv ||revista.arquivos@abneuro.org
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