Parkinson's disease effect on autonomic modulation: an analysis using geometric indices
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000200114 |
Resumo: | ABSTRACT Background: Parkinson's disease (PD) produces autonomic changes, indicating lower parasympathetic modulation and global variability, but these changes need further studying regarding geometric methods. Objective: To investigate the autonomic modulation in individuals with PD using heart rate variability (HRV) indices obtained through geometric methods. Methods: This is a cross-sectional study that assessed 50 individuals, split into two groups: PD group (PDG; n=26; 75.36±5.21 years) and control group (CG; n=24; 75.36±5.21 years). We evaluated the autonomic modulation by measuring the heart rate beat-to-beat for 30 min with the individual in supine rest using a heart rate monitor and assessed geometric indices (RRtri, TINN, SD1, SD2, SD1/SD2 ratio, and qualitative analysis of the Poincaré plot). Results: Significant reductions were found in RRtri, TINN, SD1, and SD2 indices among PDG compared to CG. Regarding the SD1/SD2 ratio, no significant changes were detected between the groups. The Poincaré plot demonstrated that individuals with PD had lower beat-to-beat dispersion in RR intervals, in addition to greater long-term dispersion of RR intervals compared to CG. Conclusions: The results suggest a reduction in the parasympathetic autonomic modulation and global variability in individuals with PD compared to controls, regardless of sex, age, and body mass index. |
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Parkinson's disease effect on autonomic modulation: an analysis using geometric indicesParkinson DiseaseAutonomic Nervous SystemPrimary DysautonomiasNeurodegenerative DiseasesABSTRACT Background: Parkinson's disease (PD) produces autonomic changes, indicating lower parasympathetic modulation and global variability, but these changes need further studying regarding geometric methods. Objective: To investigate the autonomic modulation in individuals with PD using heart rate variability (HRV) indices obtained through geometric methods. Methods: This is a cross-sectional study that assessed 50 individuals, split into two groups: PD group (PDG; n=26; 75.36±5.21 years) and control group (CG; n=24; 75.36±5.21 years). We evaluated the autonomic modulation by measuring the heart rate beat-to-beat for 30 min with the individual in supine rest using a heart rate monitor and assessed geometric indices (RRtri, TINN, SD1, SD2, SD1/SD2 ratio, and qualitative analysis of the Poincaré plot). Results: Significant reductions were found in RRtri, TINN, SD1, and SD2 indices among PDG compared to CG. Regarding the SD1/SD2 ratio, no significant changes were detected between the groups. The Poincaré plot demonstrated that individuals with PD had lower beat-to-beat dispersion in RR intervals, in addition to greater long-term dispersion of RR intervals compared to CG. Conclusions: The results suggest a reduction in the parasympathetic autonomic modulation and global variability in individuals with PD compared to controls, regardless of sex, age, and body mass index.Academia Brasileira de Neurologia - ABNEURO2021-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000200114Arquivos de Neuro-Psiquiatria v.79 n.2 2021reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/0004-282x-anp-2020-0088info:eu-repo/semantics/openAccessStoco-Oliveira,Mileide CristinaRicci-Vitor,Ana LauraVanzella,Laís ManataValente,Heloisa BalotariSilva,Vitor Eduardo dos SantosAndré,Larissa BorbaCarvalho,Augusto Cesinando deGarner,David MatthewVanderlei,Luiz Carlos Marqueseng2021-03-17T00:00:00Zoai:scielo:S0004-282X2021000200114Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2021-03-17T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Parkinson's disease effect on autonomic modulation: an analysis using geometric indices |
title |
Parkinson's disease effect on autonomic modulation: an analysis using geometric indices |
spellingShingle |
Parkinson's disease effect on autonomic modulation: an analysis using geometric indices Stoco-Oliveira,Mileide Cristina Parkinson Disease Autonomic Nervous System Primary Dysautonomias Neurodegenerative Diseases |
title_short |
Parkinson's disease effect on autonomic modulation: an analysis using geometric indices |
title_full |
Parkinson's disease effect on autonomic modulation: an analysis using geometric indices |
title_fullStr |
Parkinson's disease effect on autonomic modulation: an analysis using geometric indices |
title_full_unstemmed |
Parkinson's disease effect on autonomic modulation: an analysis using geometric indices |
title_sort |
Parkinson's disease effect on autonomic modulation: an analysis using geometric indices |
author |
Stoco-Oliveira,Mileide Cristina |
author_facet |
Stoco-Oliveira,Mileide Cristina Ricci-Vitor,Ana Laura Vanzella,Laís Manata Valente,Heloisa Balotari Silva,Vitor Eduardo dos Santos André,Larissa Borba Carvalho,Augusto Cesinando de Garner,David Matthew Vanderlei,Luiz Carlos Marques |
author_role |
author |
author2 |
Ricci-Vitor,Ana Laura Vanzella,Laís Manata Valente,Heloisa Balotari Silva,Vitor Eduardo dos Santos André,Larissa Borba Carvalho,Augusto Cesinando de Garner,David Matthew Vanderlei,Luiz Carlos Marques |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Stoco-Oliveira,Mileide Cristina Ricci-Vitor,Ana Laura Vanzella,Laís Manata Valente,Heloisa Balotari Silva,Vitor Eduardo dos Santos André,Larissa Borba Carvalho,Augusto Cesinando de Garner,David Matthew Vanderlei,Luiz Carlos Marques |
dc.subject.por.fl_str_mv |
Parkinson Disease Autonomic Nervous System Primary Dysautonomias Neurodegenerative Diseases |
topic |
Parkinson Disease Autonomic Nervous System Primary Dysautonomias Neurodegenerative Diseases |
description |
ABSTRACT Background: Parkinson's disease (PD) produces autonomic changes, indicating lower parasympathetic modulation and global variability, but these changes need further studying regarding geometric methods. Objective: To investigate the autonomic modulation in individuals with PD using heart rate variability (HRV) indices obtained through geometric methods. Methods: This is a cross-sectional study that assessed 50 individuals, split into two groups: PD group (PDG; n=26; 75.36±5.21 years) and control group (CG; n=24; 75.36±5.21 years). We evaluated the autonomic modulation by measuring the heart rate beat-to-beat for 30 min with the individual in supine rest using a heart rate monitor and assessed geometric indices (RRtri, TINN, SD1, SD2, SD1/SD2 ratio, and qualitative analysis of the Poincaré plot). Results: Significant reductions were found in RRtri, TINN, SD1, and SD2 indices among PDG compared to CG. Regarding the SD1/SD2 ratio, no significant changes were detected between the groups. The Poincaré plot demonstrated that individuals with PD had lower beat-to-beat dispersion in RR intervals, in addition to greater long-term dispersion of RR intervals compared to CG. Conclusions: The results suggest a reduction in the parasympathetic autonomic modulation and global variability in individuals with PD compared to controls, regardless of sex, age, and body mass index. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000200114 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000200114 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0004-282x-anp-2020-0088 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.79 n.2 2021 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
_version_ |
1754212788199227392 |