Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma
Autor(a) principal: | |
---|---|
Data de Publicação: | 2012 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Arquivos de neuro-psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900012 |
Resumo: | Dysembryoplastic neuroepithelial tumor (DNT), described in 1988 and introduced in the WHO classification in 1993, affects predominantly children or young adults causing intractable complex partial seizures. Since it is benign and treated with surgical resection, its recognition is important. It has similarities with low-grade gliomas and gangliogliomas, which may recur and become malignant. OBJECTIVES: To investigate whether DNT was previously diagnosed as astrocytoma, oligodendroglioma, or ganglioglioma and to determine its frequency in a series of low-grade glial/glio-neuronal tumors. METHODS: Clinical, radiological, and histological aspects of 58 tumors operated from 1978 to 2008, classified as astrocytomas (32, including 8 pilocytic), oligodendrogliomas (12), gangliogliomas (7), and DNT (7), were reviewed. RESULTS: Four new DNT, one operated before 1993, previously classified as astrocytoma (3) and oligodendroglioma (1), were identified. One DNT diagnosed in 2002 was classified once more as angiocentric glioma. Therefore, 10 DNT (17.2%) were identified. CONCLUSIONS: Clinical-radiological and histopathological correlations have contributed to diagnose the DNT. |
id |
ABNEURO-1_7b4d07ee9734dad9738a5777784fe694 |
---|---|
oai_identifier_str |
oai:scielo:S0004-282X2012000900012 |
network_acronym_str |
ABNEURO-1 |
network_name_str |
Arquivos de neuro-psiquiatria (Online) |
repository_id_str |
|
spelling |
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendrogliomadysembryoplastic neuroepithelial tumorlow-grade gliomasepilepsyDysembryoplastic neuroepithelial tumor (DNT), described in 1988 and introduced in the WHO classification in 1993, affects predominantly children or young adults causing intractable complex partial seizures. Since it is benign and treated with surgical resection, its recognition is important. It has similarities with low-grade gliomas and gangliogliomas, which may recur and become malignant. OBJECTIVES: To investigate whether DNT was previously diagnosed as astrocytoma, oligodendroglioma, or ganglioglioma and to determine its frequency in a series of low-grade glial/glio-neuronal tumors. METHODS: Clinical, radiological, and histological aspects of 58 tumors operated from 1978 to 2008, classified as astrocytomas (32, including 8 pilocytic), oligodendrogliomas (12), gangliogliomas (7), and DNT (7), were reviewed. RESULTS: Four new DNT, one operated before 1993, previously classified as astrocytoma (3) and oligodendroglioma (1), were identified. One DNT diagnosed in 2002 was classified once more as angiocentric glioma. Therefore, 10 DNT (17.2%) were identified. CONCLUSIONS: Clinical-radiological and histopathological correlations have contributed to diagnose the DNT.Academia Brasileira de Neurologia - ABNEURO2012-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900012Arquivos de Neuro-Psiquiatria v.70 n.9 2012reponame:Arquivos de neuro-psiquiatria (Online)instname:Academia Brasileira de Neurologiainstacron:ABNEURO10.1590/S0004-282X2012000900012info:eu-repo/semantics/openAccessDozza,Diego CassolRodrigues,Flávio FreinkelChimelli,Leilaeng2012-09-13T00:00:00Zoai:scielo:S0004-282X2012000900012Revistahttp://www.scielo.br/anphttps://old.scielo.br/oai/scielo-oai.php||revista.arquivos@abneuro.org1678-42270004-282Xopendoar:2012-09-13T00:00Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologiafalse |
dc.title.none.fl_str_mv |
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma |
title |
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma |
spellingShingle |
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma Dozza,Diego Cassol dysembryoplastic neuroepithelial tumor low-grade gliomas epilepsy |
title_short |
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma |
title_full |
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma |
title_fullStr |
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma |
title_full_unstemmed |
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma |
title_sort |
Dysembryoplastic neuroepithelial tumor originally diagnosed as astrocytoma and oligodendroglioma |
author |
Dozza,Diego Cassol |
author_facet |
Dozza,Diego Cassol Rodrigues,Flávio Freinkel Chimelli,Leila |
author_role |
author |
author2 |
Rodrigues,Flávio Freinkel Chimelli,Leila |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Dozza,Diego Cassol Rodrigues,Flávio Freinkel Chimelli,Leila |
dc.subject.por.fl_str_mv |
dysembryoplastic neuroepithelial tumor low-grade gliomas epilepsy |
topic |
dysembryoplastic neuroepithelial tumor low-grade gliomas epilepsy |
description |
Dysembryoplastic neuroepithelial tumor (DNT), described in 1988 and introduced in the WHO classification in 1993, affects predominantly children or young adults causing intractable complex partial seizures. Since it is benign and treated with surgical resection, its recognition is important. It has similarities with low-grade gliomas and gangliogliomas, which may recur and become malignant. OBJECTIVES: To investigate whether DNT was previously diagnosed as astrocytoma, oligodendroglioma, or ganglioglioma and to determine its frequency in a series of low-grade glial/glio-neuronal tumors. METHODS: Clinical, radiological, and histological aspects of 58 tumors operated from 1978 to 2008, classified as astrocytomas (32, including 8 pilocytic), oligodendrogliomas (12), gangliogliomas (7), and DNT (7), were reviewed. RESULTS: Four new DNT, one operated before 1993, previously classified as astrocytoma (3) and oligodendroglioma (1), were identified. One DNT diagnosed in 2002 was classified once more as angiocentric glioma. Therefore, 10 DNT (17.2%) were identified. CONCLUSIONS: Clinical-radiological and histopathological correlations have contributed to diagnose the DNT. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900012 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000900012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0004-282X2012000900012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria v.70 n.9 2012 reponame:Arquivos de neuro-psiquiatria (Online) instname:Academia Brasileira de Neurologia instacron:ABNEURO |
instname_str |
Academia Brasileira de Neurologia |
instacron_str |
ABNEURO |
institution |
ABNEURO |
reponame_str |
Arquivos de neuro-psiquiatria (Online) |
collection |
Arquivos de neuro-psiquiatria (Online) |
repository.name.fl_str_mv |
Arquivos de neuro-psiquiatria (Online) - Academia Brasileira de Neurologia |
repository.mail.fl_str_mv |
||revista.arquivos@abneuro.org |
_version_ |
1754212773806473216 |