Gender differences in obsessive-compulsive disorder: a literature review

Detalhes bibliográficos
Autor(a) principal: Mathis,Maria Alice de
Data de Publicação: 2011
Outros Autores: Alvarenga,Pedro de, Funaro,Guilherme, Torresan,Ricardo Cezar, Moraes,Ivanil, Torres,Albina Rodrigues, Zilberman,Monica L, Hounie,Ana Gabriela
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462011000400014
Resumo: INTRODUCTION: Obsessive-compulsive disorder (OCD) is a heterogeneous condition, in which subtypes have been proposed. Previous studies suggested that gender plays a relevant role in OCD phenotypic expression. This study aimed to review the literature on gender differences in clinical, genetic or familial aspects of OCD. METHOD: A conventional review was conducted, including all papers that investigated demographic, clinical, and genetic aspects of OCD according to gender. The search was based on data available in Medline and PsycINFO databases in the last 20 years, using as keywords: obsessive-compulsive disorder; and: gender, sex, male, female, demographic characteristics, clinical features, clinical characteristics, genetic, genes, genetics gender OCD, genes OCD, genes OCD males, genes OCD females. RESULTS: Sixty three of 487 phenotypical and genetics studies were selected. Most studies indicate that male patients are more likely than females to be single, present early onset of symptoms and chronic course of the disorder, greater social impairment, more sexual-religious and aggressive symptoms, and greater comorbidity with tic and substance use disorders. Female patients present more contamination/cleaning symptoms and greater comorbidity with eating and impulse-control disorders. Genetic and family studies are inconclusive, but suggest that gender may play a role in the disease expression. CONCLUSIONS: Gender is a relevant factor that should be taken into account when evaluating OCD patients. More studies are necessary to determine whether in fact it defines a homogeneous and particular group in OCD.
id ABP-1_4b4c715abf10019eca905142db05020d
oai_identifier_str oai:scielo:S1516-44462011000400014
network_acronym_str ABP-1
network_name_str Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
repository_id_str
spelling Gender differences in obsessive-compulsive disorder: a literature reviewObsessive-compulsive disorderGender identitySexPhenotypeGeneticsINTRODUCTION: Obsessive-compulsive disorder (OCD) is a heterogeneous condition, in which subtypes have been proposed. Previous studies suggested that gender plays a relevant role in OCD phenotypic expression. This study aimed to review the literature on gender differences in clinical, genetic or familial aspects of OCD. METHOD: A conventional review was conducted, including all papers that investigated demographic, clinical, and genetic aspects of OCD according to gender. The search was based on data available in Medline and PsycINFO databases in the last 20 years, using as keywords: obsessive-compulsive disorder; and: gender, sex, male, female, demographic characteristics, clinical features, clinical characteristics, genetic, genes, genetics gender OCD, genes OCD, genes OCD males, genes OCD females. RESULTS: Sixty three of 487 phenotypical and genetics studies were selected. Most studies indicate that male patients are more likely than females to be single, present early onset of symptoms and chronic course of the disorder, greater social impairment, more sexual-religious and aggressive symptoms, and greater comorbidity with tic and substance use disorders. Female patients present more contamination/cleaning symptoms and greater comorbidity with eating and impulse-control disorders. Genetic and family studies are inconclusive, but suggest that gender may play a role in the disease expression. CONCLUSIONS: Gender is a relevant factor that should be taken into account when evaluating OCD patients. More studies are necessary to determine whether in fact it defines a homogeneous and particular group in OCD.Associação Brasileira de Psiquiatria2011-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462011000400014Brazilian Journal of Psychiatry v.33 n.4 2011reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)instname:Associação Brasileira de Psiquiatria (ABP)instacron:ABP10.1590/S1516-44462011000400014info:eu-repo/semantics/openAccessMathis,Maria Alice deAlvarenga,Pedro deFunaro,GuilhermeTorresan,Ricardo CezarMoraes,IvanilTorres,Albina RodriguesZilberman,Monica LHounie,Ana Gabrielaeng2013-04-05T00:00:00Zoai:scielo:S1516-44462011000400014Revistahttp://www.bjp.org.br/ahead_of_print.asphttps://old.scielo.br/oai/scielo-oai.php||rbp@abpbrasil.org.br1809-452X1516-4446opendoar:2013-04-05T00:00Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)false
dc.title.none.fl_str_mv Gender differences in obsessive-compulsive disorder: a literature review
title Gender differences in obsessive-compulsive disorder: a literature review
spellingShingle Gender differences in obsessive-compulsive disorder: a literature review
Mathis,Maria Alice de
Obsessive-compulsive disorder
Gender identity
Sex
Phenotype
Genetics
title_short Gender differences in obsessive-compulsive disorder: a literature review
title_full Gender differences in obsessive-compulsive disorder: a literature review
title_fullStr Gender differences in obsessive-compulsive disorder: a literature review
title_full_unstemmed Gender differences in obsessive-compulsive disorder: a literature review
title_sort Gender differences in obsessive-compulsive disorder: a literature review
author Mathis,Maria Alice de
author_facet Mathis,Maria Alice de
Alvarenga,Pedro de
Funaro,Guilherme
Torresan,Ricardo Cezar
Moraes,Ivanil
Torres,Albina Rodrigues
Zilberman,Monica L
Hounie,Ana Gabriela
author_role author
author2 Alvarenga,Pedro de
Funaro,Guilherme
Torresan,Ricardo Cezar
Moraes,Ivanil
Torres,Albina Rodrigues
Zilberman,Monica L
Hounie,Ana Gabriela
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mathis,Maria Alice de
Alvarenga,Pedro de
Funaro,Guilherme
Torresan,Ricardo Cezar
Moraes,Ivanil
Torres,Albina Rodrigues
Zilberman,Monica L
Hounie,Ana Gabriela
dc.subject.por.fl_str_mv Obsessive-compulsive disorder
Gender identity
Sex
Phenotype
Genetics
topic Obsessive-compulsive disorder
Gender identity
Sex
Phenotype
Genetics
description INTRODUCTION: Obsessive-compulsive disorder (OCD) is a heterogeneous condition, in which subtypes have been proposed. Previous studies suggested that gender plays a relevant role in OCD phenotypic expression. This study aimed to review the literature on gender differences in clinical, genetic or familial aspects of OCD. METHOD: A conventional review was conducted, including all papers that investigated demographic, clinical, and genetic aspects of OCD according to gender. The search was based on data available in Medline and PsycINFO databases in the last 20 years, using as keywords: obsessive-compulsive disorder; and: gender, sex, male, female, demographic characteristics, clinical features, clinical characteristics, genetic, genes, genetics gender OCD, genes OCD, genes OCD males, genes OCD females. RESULTS: Sixty three of 487 phenotypical and genetics studies were selected. Most studies indicate that male patients are more likely than females to be single, present early onset of symptoms and chronic course of the disorder, greater social impairment, more sexual-religious and aggressive symptoms, and greater comorbidity with tic and substance use disorders. Female patients present more contamination/cleaning symptoms and greater comorbidity with eating and impulse-control disorders. Genetic and family studies are inconclusive, but suggest that gender may play a role in the disease expression. CONCLUSIONS: Gender is a relevant factor that should be taken into account when evaluating OCD patients. More studies are necessary to determine whether in fact it defines a homogeneous and particular group in OCD.
publishDate 2011
dc.date.none.fl_str_mv 2011-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462011000400014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462011000400014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1516-44462011000400014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
publisher.none.fl_str_mv Associação Brasileira de Psiquiatria
dc.source.none.fl_str_mv Brazilian Journal of Psychiatry v.33 n.4 2011
reponame:Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
instname:Associação Brasileira de Psiquiatria (ABP)
instacron:ABP
instname_str Associação Brasileira de Psiquiatria (ABP)
instacron_str ABP
institution ABP
reponame_str Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
collection Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
repository.name.fl_str_mv Brazilian Journal of Psychiatry (São Paulo. 1999. Online) - Associação Brasileira de Psiquiatria (ABP)
repository.mail.fl_str_mv ||rbp@abpbrasil.org.br
_version_ 1754212555522310144